“…Influenza C virus is ubiquitous and usually causes a mild upper respiratory tract illness in children and lower respiratory tract illnesses such as bronchitis and pneumonia in infants and children (1,2). To clarify the epidemiology of acute viral respiratory infections in children in Yamagata, Japan, as a part of the National Epidemiological Surveillance of Infectious Diseases, Japan based on the Infectious Diseases Control Law, we performed virus isolation using HHVM, HHVMRG, and HHVe6MRG microplates, containing HEF, HEp-2, Vero or VeroE6, MDCK, RD-18S, and GMK cell lines as well as the HMV-II cell line, in part, for the isolation of viruses, including influenza virus C (1,3-7).…”