Clinical Efficacy and Prognostic Factors of Chemoreduction Combined with Topical Treatment for Advanced Intraocular Retinoblastoma

Liu, Yan; Xi, Zhang; Liu, Fang; Wang, Kelei

doi:10.7314/apjcp.2014.15.18.7805

Cited by 4 publications

(2 citation statements)

References 16 publications

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“…A very recent study on clinical efficacy and prognostic factors of chemoreduction combined with local therapy for advanced intraocular retinoblastoma also indicated that chemoreduction combined with TTT, cryotherapy or 125 I episcleral plaque brachytherapy could effectively control retinoblastoma in a short-term with eyeball retention rate of 81.82% and high recurrence rate of 41.18%. 15 …”

Section: Discussionmentioning

confidence: 99%

“…Overall, retinoblastoma recurrence or focal new growth usually occurs within few years after completion of the initial treatment, and rarely develops more than a year after treatment. Most literature reported recurrence or local growth within 2–4 months and maximum up to 4 years after the initial treatment, 5 , 6 , 7 , 15 and recurrences and death usually occurs within the first 2 years after diagnosis and treatment. 5 Most commonly new tumor growth or recurrence appeared in the eyes of children diagnosed at a very young age or who were members of a pedigree with retinoblastoma.…”

Section: Discussionmentioning

confidence: 99%

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Unusually very late-onset new growth of intraocular retinoblastoma: A case report and review of literature

Gelaw

Shoukry

Othman

2017

American Journal of Ophthalmology Case Reports

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PurposeTo report a patient who presented with a very late-onset new growth of intraocular retinoblastoma, which occurred 11 years after the initial combined treatment.ObservationsA 12-year-old monoophthalmic female patient presented with bilateral familial retinoblastoma showing new growth of intraocular tumor after 11 years of complete regression following combined local and systemic treatments. The new tumor growth was treated with diode laser transpupillary thermotherapy, ruthenium-106 plaque radiotherapy and adjuvant intravenous chemotherapy and the tumor regressed.Conclusions and importanceDespite initial satisfactory treatment and complete regression of the tumor, very late-onset new growth of intraocular retinoblastoma can occur. Hence, life-long follow-up in all patients with retinoblastoma is warranted, given the risk for new tumor formation even later in life. To our knowledge, this is the first report of new growth of intraocular retinoblastoma after regression for more than a decade.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Unusually very late-onset new growth of intraocular retinoblastoma: A case report and review of literature

Gelaw

Shoukry

Othman

2017

American Journal of Ophthalmology Case Reports

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Retinoblastoma and vision

Warda

Naeem

Roelofs

et al. 2022

Eye

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The assessment of vision has a growing importance in the management of retinoblastoma in the era of globe-conserving therapy, both prior to and after treatment. As survival rates approach 98–99% and globe salvage rates reach ever-higher levels, it is important to provide families with information regarding the visual outcomes of different treatments. We present an overview of the role of vision in determining the treatment given and the impact of complications of treatment. We also discuss screening and treatment strategies that can be used to maximise vision.

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Vision and visual potential for perifoveal retinoblastoma after optical coherence tomographic-guided sequential laser photocoagulation

et al. 2018

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Clinical Efficacy and Prognostic Factors of Chemoreduction Combined with Topical Treatment for Advanced Intraocular Retinoblastoma

Cited by 4 publications

References 16 publications

Unusually very late-onset new growth of intraocular retinoblastoma: A case report and review of literature

Unusually very late-onset new growth of intraocular retinoblastoma: A case report and review of literature

Retinoblastoma and vision

Vision and visual potential for perifoveal retinoblastoma after optical coherence tomographic-guided sequential laser photocoagulation

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