CLINICAL ASPECTS OF INFECTION WITH <i>YERSINIA ENTEROCOLITICA</i> IN ADULTS

Feeney, Gerald F.X.; Kerlin, Paul; Sampson, John A.

doi:10.1111/j.1445-5994.1987.tb00045.x

Cited by 13 publications

(4 citation statements)

References 3 publications

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“…3 Other studies have found a duration of illness ranging from 12 to 22 days. [11][12][13][14][15] Post-infectious complications can occur after YE gastroenteritis, the most common being erythema nodosum and reactive arthritis. Erythema nodosum is most common in women, and typically appears within a month of the first symptoms of gastroenteritis.…”

Section: Introductionmentioning

confidence: 99%

Yersinia enterocolitica: A Follow-up of the Outbreak in the Norwegian Armed Forces in 2014

et al. 2021

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Introduction In the spring of 2014, there was an outbreak of Yersinia enterocolitica (YE) gastroenteritis in four Norwegian military camps—the largest outbreak ever reported in Norway. YE is usually transmitted via food, and the gastrointestinal disease caused by the bacterium is considered a public health problem in several countries. Common symptoms of YE gastroenteritis are abdominal pain, diarrhea, fever, nausea, and vomiting. Post-infectious complications can occur after YE gastroenteritis, the most common of which are erythema nodosum and reactive arthritis. Based on self-reported data, we describe the duration of illness, the duration of any absence from service, and the incidence of symptoms of post-infectious complications in two groups of servicepeople: one diagnosed with YE gastroenteritis and the other with an unspecified acute infectious gastroenteritis. Materials and Methods The Norwegian Armed Forces Health Register (NAFHR) is a central health register that contains data from conscripts and from military and civilian personnel in the Norwegian Armed Forces. In this study, we identified all individuals with a diagnosis of YE gastroenteritis in the NAFHR in the period from January 1 to June 30, 2014 (n = 128) as well as all those with a diagnosis of an unspecified acute infectious gastroenteritis in the same period (n = 323) to participate as controls. In October 2018, a link to an internet-based questionnaire was distributed by e-mail to all identified individuals. The questionnaires collected data on the duration of illness, the duration of absence from service, and the incidence of symptoms of post-infectious complications. Results Of all those who received the questionnaire, 72 (59%) were included in the YE group and 117 people (36%) were included in the control group. Half of those in the YE group were ill for more than 13 days, while almost all (90%) of those in the control group recovered after 1 week. There were no differences between the groups in the incidence of symptoms of post-infectious complications during the 6 weeks after recovery. There was a significantly larger proportion of officers than conscripts in the YE group who reported symptoms of post-infectious complications. None of the respondents reported symptoms of post-infectious complications in the 6 months after the termination of military service. Conclusion One strength of this study is that we were able to investigate a large outbreak of YE gastroenteritis in a group of individuals with good underlying health. Weaknesses are the low response rate, especially in the control group, and the fact that we sent out the questionnaire >4 years after the acute gastroenteritis occurred. YE gastroenteritis among personnel in the Norwegian Armed Forces was associated with a significantly longer duration of illness and a longer duration of absence from service than that resulting from an unspecified acute infectious gastroenteritis. However, YE gastroenteritis was not associated with more symptoms of post-infectious complications.

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Section: Introductionmentioning

confidence: 99%

Yersinia enterocolitica: A Follow-up of the Outbreak in the Norwegian Armed Forces in 2014

et al. 2021

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“…This process, which has been termed "invasion, appears to be a crucial pathogenic trait. The invasive phenomenon is exemplified by Yersinia enterocolitica and Yersinia pseudotuberculosis and contributes to their capacity to cause a variety of gastrointestinal infections in humans (Weber et al, 1970;Feeney et al ., 1987) . Examination of infected tissues from patients with yersinosis shows the intracellular location of these bacteria; their invasive ability can also be demonstrated experimentally by in vitro studies with a variety of cultured mammalian cells (Miller et al ., 1988).…”

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confidence: 99%

The invasin protein of Yersinia enterocolitica: internalization of invasin-bearing bacteria by eukaryotic cells is associated with reorganization of the cytoskeleton.

Young

Falkow

Schoolnik

1992

The Journal of Cell Biology

146

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Abstract. Yersinia enterocolitica, a facultative intracellular pathogen of mammals, readily enters (i.e., invades) cultured eukaryotic cells, a process that can be conferred by the cloned inv locus of the species. We have studied the mechanism by which the product of inv, a microbial outer membrane protein termed "invasin;" mediates the internalization of bacteria by HEp-2 cells and chicken embryo fibroblasts . Invasinbearing bacteria initially bound the filopodia and the leading edges of cultured cells . Multiple points of contact between the bacterial surface and the surface of the cell ensued and led to the internalization of the bacterium within an endocytic vacuole ; the same multistep process could be induced by an inert particle coated with invasin-containing membranes . Both adherence and internalization were blocked by an antisera directed against the 0 1 integrin cell-adherence

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“…La Yersinia enterocolítica es el tercer patógeno entérico más frecuente tras la Salmonella y el Campylobacter yeyuni, siendo una causa emergente de diarrea en al adulto, pudiendo ocasionar una síndrome apendicular (7).…”

Section: Zoonosis Emergentesunclassified