Clinical and diagnostic features of dengue haemorrhagic fever in children

Reddy, Gomathi Chenna; Nagendra, Kanchana

doi:10.18203/2349-3291.ijcp20181387

Cited by 4 publications

(5 citation statements)

References 13 publications

(15 reference statements)

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“…Considering presenting symptoms next to fever (72.55%), headache (52.94%), vomiting (41.18%), myalgia (37.25%) and hemorrhagic manifestations (21.57%) were commonly found in this study. Reddy GC et al 12 in their study found fever as most common symptom, followed by skin rash (56.0%), myalgia (52.0%) and head ache (48.0%) were the symptoms which is little bit different from this study but our findings were similar to study of Kumar A et al 13 Abdominal pain and vomiting were also common presenting symptom in this study which may often lead to a delay in the diagnosis of dengue. 14 Deranged liver operate in dengue fever infection is a result of the direct impact of the virus on liver cells or the unregulated host response against the virus may cause fulminant hepatic failure from acute hepatitis and massive necrosis of the liver, causing hepatic encephalopathy and even death.…”

Section: Discussionsupporting

confidence: 83%

Dengue Fever: Clinical Characteristics of A Tertiary Care Hospital Study

Ahsan

Hussain

Hoque

et al. 2020

Bangladesh J Child Health

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Background: Incidence of dengue infection has increased worldwide and has become a significant public health concern. Clinical suspicion based on the frequency of symptoms is very important for early diagnosis. Objectives: To observe the clinical characteristics of serologically confirmed hospitalized cases of dengue fever. Material and Methods: This cross-sectional study was done among admitted children with dengue infection in Dhaka Shishu (Children) Hospital from July 2018 to October 2018. The diagnosis of dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS) were established according to the World Health Organization (WHO) classification criteria. Cases who were NS1 antigen and IgM dengue antibody positive included in this study. Results: Among 51 serologically confirmed dengue fever patients, mean age was 6.66 ± 3.69 years. Majority of the cases (74.5%) were less than 10 years of age, 60.8% were male, 39.2% were female, and 88.23% of patients came from urban areas. Classic DF was found in 74.5% of patients, while 25.49% of patients DHF, and 11.7% DSS. Fever was the most common (72.55%) symptom followed by headache, vomiting and myalgia. Hemorrhagic manifestations found in 21.57% of cases. The most common complications were hepatic dysfunction (47.09%) followed by renal impairment, encephalopathy, multi-organ failure, and ARDS. Conclusion: The majorities of dengue cases were from urban areas, below ten years of age and classical DF. Besides fever other common symptoms were headache, vomiting and myalgia. The most common complications were hepatic dysfunction, renal impairment and encephalopathy. Bangladesh J Child Health 2020; VOL 44 (1) :30-33

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Section: Discussionsupporting

confidence: 83%

Dengue Fever: Clinical Characteristics of A Tertiary Care Hospital Study

Ahsan

Hussain

Hoque

et al. 2020

Bangladesh J Child Health

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“…There were similar findings in studies by Malleshappa K, et al 20 , Arora SK, et al 19 and Reddy A, et al 13 . Respiratory distress was significantly associated with SD which was similar to studies by Reddy A, et al 13 , Naaraayan SA, et al 21 and Reddy GC, et al 22 . It might be due to plural effusion or pulmonary oedema.…”

Section: Discussionsupporting

confidence: 89%

“…Similar findings were seen in the study by Afroze S, et al 15 . On chest xray, bilateral pleural effusion was associated with SD, which was similar to the study by Reddy GC, et al 22 , On USG of abdomen, ascites was the common finding associated with SD. There was a similar finding in the study by Pothepragada S, et al 25 on univariate analysis.…”

Section: Discussionsupporting

confidence: 88%

Clinical, haematological and radiological predictors of severe dengue in the paediatric population

Firoz

Mittal²,

Teja³

et al. 2023

Sri Lanka J Child Health

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Background: Dengue is a mosquito borne viral infection which has higher morbidity and mortality in the paediatric age group than in the adult group. Objectives: To assess the clinical and haematological parameters for early diagnosis and better management of severe dengue (SD). Method: A prospective observational study was conducted in the Department of Paediatrics, FH Medical College, Agra, India from September 2021 to February 2022. Confirmed dengue cases aged 1 month to 18 years were included in the study. Cases were classified into two groups, non-severe dengue (dengue fever and dengue with warning signs) and SD. All cases had complete history, clinical examination, and relevant investigations. Bivariate analysis was performed using Chi-square test and p value <0.05 was considered significant. Results: A total of 801 confirmed cases of dengue, admitted in FH Medical College, were included in study. Of them, 564 had non-severe dengue and 237 had SD. Clinical features like gastrointestinal bleeding, lethargy, low pulse pressure, altered consciousness, ascites, bilateral pleural effusion and oliguria were significantly higher in SD as compared to non-severe dengue (p-value <0.05). Haematological parameters like severe thrombocytopenia, raised haematocrit (HCT), liver transaminase levels, deranged prothrombin time (PT) / international normalised ratio (INR), hypoalbuminaemia and radiological features like bilateral pleural effusion and ascites were significantly associated (p-value <0.05) with SD. Conclusions: In this study, clinical features like erythema, abdominal pain, vomiting, jaundice, cough, hepato-splenomegaly, severe bleeding, lethargy, low pulse pressure, altered consciousness, ascites and bilateral pleural effusion were significantly associated with SD compared to nonsevere dengue. Haematological parameters like severe thrombocytopenia, raised HCT, raised transaminase levels and deranged PT/INR and hypoalbuminaemia were also significantly associated with SD. Sri Lanka Journal of Child Health, 2023: 52(2): 188-194

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“…In another study done by Reddy GC et al; [16] found that the anorexia (81.0%), nausea/vomiting (7 9 .0%), headache (5I.4%) and bleeding tendency were common features. In comparison to adults, apart from these symptoms, positive tourniquet test, abdominal tenderness, convalescent rash, pleural effusion and ascites due to plasma leakage as a result of low serum albumin and sodium were also reported and further showed a higher association of bleeding in children, but requirement of transfusion was more in adults compared to children [17] .…”

Section: Discussionmentioning

confidence: 98%

Clinical assessment of dermatological manifestations of dengue fever in a tertiary care center of Karimnagar

Rachakonda¹

2019

jmscr

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Background: The changing epidemiology of dengue fevers in terms of strains, severity and geographic distribution is raising concern in India. Dengue virus infection, the most common and widespread arthropod-borne viral infection has grown dramatically in the last 50 years globally. Most commonly adults are affected by dengue, but the pediatric population is more vulnerable. Method: A hospital-based study was conducted for a period of 2 months (June -July 2019) among 134 cases of dengue fever between the age group of 3 months to 15 years presenting with symptoms & signs suggestive of dengue fever as per WHO criteria were recorded and were analyzed in detail with more emphasis on onset of skin lesions, their morphology, distribution, sites involved and progression in study area. Results: About 134 patients with dengue fever were enrolled, 70.1 % were males and 29.9 % were females. Cutaneous manifestations were present in 50.7% of patients while mucous manifestation was seen in 8.9% of patients. Bleeding manifestations were seen in 28.4% of cases with petechiae (26.3%) was the commonest manifestation. Conclusion:Though dengue is a systemic illness, more than half of the patients showed cutaneous involvement and 50% of patients had an onset of skin rash consistently with fever which can help in suspecting dengue illness. Thus skin can be involved in various ways in children with dengue fever and can help diagnose the illness clinically, especially in places with inadequate laboratory support.

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Clinical and diagnostic features of dengue haemorrhagic fever in children

Cited by 4 publications

References 13 publications

Dengue Fever: Clinical Characteristics of A Tertiary Care Hospital Study

Dengue Fever: Clinical Characteristics of A Tertiary Care Hospital Study

Clinical, haematological and radiological predictors of severe dengue in the paediatric population

Clinical assessment of dermatological manifestations of dengue fever in a tertiary care center of Karimnagar

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