Cleft Lip and Palate in Tehran

Taher, Abbas

doi:10.1597/1545-1569(1992)029<0015:clapit>2.3.co;2

Cited by 17 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Clefts of the lip and/or palate (CL/P) are the most common congenital anomalies to affect the orofacial region. The epidemiology of CL/P has been studied extensively in various populations and ethnic groups (Menegotto and Salzano, 1991; Taher, 1992; Gregg et al, 1994; Kozelj, 1996; Murray et al, 1997; Hagberg et al, 1998; Shapira et al, 1999; Cooper et al, 2000; Msamati et al, 2000; Natsume et al, 2000a; Rajabian and Sherkat, 2000; Kim et al, 2002; Sipek et al, 2002; Blanco-Davila, 2003, Elahi et al, 2004; Magdalenic-Mestrovic and Bagatin, 2005; Suleiman et al, 2005; Gundlach and Maus, 2006; Jamilian et al, 2007).…”

mentioning

confidence: 99%

“…Although the epidemiology of CL/P has been studied in many populations and countries, few epidemiologic studies have been performed in Iran, and their results are conflicting. In a study evaluating the epidemiology of CL/P in Iran, Taher (1992) reported a birth prevalence of 3.73 per 1000. Jamilian et al (2007) reported a birth prevalence of 2.14 per 1000 for CL/P in Iran.…”

mentioning

confidence: 99%

See 1 more Smart Citation

An Epidemiologic Study of Orofacial Clefts in Hamedan City, Iran: A 15-Year Study

Zandi

Heidari

2011

The Cleft Palate-Craniofacial Journal

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

An Epidemiologic Study of Orofacial Clefts in Hamedan City, Iran: A 15-Year Study

Zandi

Heidari

2011

The Cleft Palate-Craniofacial Journal

View full text Add to dashboard Cite

show abstract

“…Although they had used his cases as their own controls, and thus reduced selection bias, they did not adjust for the effect of parents' increasing age on malformation occurrence. Taher et al[28] claimed that the use of mustard gas in the Iran-Iraq conflict might have increased the number of cleft lip and cleft palate in children, however, they were not able to establish any causal effect between these two events, nor could they exclude the effects of other possible causes.…”

Section: Discussionmentioning

confidence: 99%

Childhood physical abnormalities following paternal exposure to sulfur mustard gas in Iran: a case-control study

et al. 2010

View full text Add to dashboard Cite

BackgroundMustard gas, a known chemical weapon, was used during the Iran-Iraq war of 1980-1988. We aimed to determine if exposure to mustard gas among men was significantly associated with abnormalities and disorders among progenies.MethodsUsing a case-control design, we identified all progenies of Sardasht men (exposed group, n = 498), who were born at least nine months after the exposure, compared to age-matched controls in Rabat, a nearby city (non-exposed group, n = 689). We conducted a thorough medical history, physical examination, and appropriate paraclinical studies to detect any physical abnormality and/or disorder. Given the presence of correlated data, we applied Generalized Estimating Equation (GEE) multivariable models to determine associations.ResultsThe overall frequency of detected physical abnormalities and disorders was significantly higher in the exposed group (19% vs. 11%, Odds Ratio [OR] 1.93, 95% Confidence Interval [CI], 1.37-2.72, P = 0.0002). This was consistent across sexes. Congenital anomalies (OR 3.54, 95% CI, 1.58-7.93, P = 0.002) and asthma (OR, 3.12, 95% CI, 1.43-6.80, P = 0.004) were most commonly associated with exposure. No single abnormality was associated with paternal exposure to mustard gas.ConclusionOur study demonstrates a generational effect of exposure to mustard gas. The lasting effects of mustard gas exposure in parents effects fertility and may impact child health and development in the long-term.

show abstract

“…Since then, it has been recognized as a radiomimetic (5) and a human carcinogen (24,26). It may also be teratogenic and mutagenic (27,28). Mustard is an alkylating agent, and once absorbed, its toxic effects result from chemical reactions with cellular constituents.…”

Section: Ch2-ch2-ci S Ch2-ch2-cimentioning

confidence: 99%

Hazards of chemical weapons release during war: new perspectives.

Reutter

1999

Environ Health Perspect

View full text Add to dashboard Cite

The two major threat classes of chemical weapons are mustard gas and the nerve agents, and this has not changed in over 50 years. Both types are commonly called gases, but they are actually liquids that are not re ly voatile. These agents were designed specifically to harm people by any route of exposure and to be effective at low doses. Mustard gas was used in World War I, and the nerve agents were developed shortly before, during, and after World War II. Our perception of the potency of chemical weapons has changed, as well as our concern over potential effects of prolonged exposures to low doses and potential target populations that indude women and cildren. Many of the toxicologic studies and human toxicity esmates for both mustard and nerve agents were designed for the purpose of quickly developing maximal casualties in the least sensitive male soldier. The 'toxcity" of the chemical weapons has not changed, but our perception of 'toxicity" has.

show abstract

Cleft Lip and Palate in Tehran

Cited by 17 publications

References 0 publications

An Epidemiologic Study of Orofacial Clefts in Hamedan City, Iran: A 15-Year Study

An Epidemiologic Study of Orofacial Clefts in Hamedan City, Iran: A 15-Year Study

Childhood physical abnormalities following paternal exposure to sulfur mustard gas in Iran: a case-control study

Hazards of chemical weapons release during war: new perspectives.

Contact Info

Product

Resources

About