An Epidemiologic Study of Orofacial Clefts in Hamedan City, Iran: A 15-Year Study

Zandi, Mohammad; Heidari, Ali

doi:10.1597/09-035

Cited by 25 publications

(35 citation statements)

References 48 publications

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“…Indeed, we found a higher frequency of associated congenital malformations, whereas African studies found lower frequencies between 4 and10.5% [18, 19]. Our result, however, was lower than in some reports from the Middle East and Asia where [20] found a frequency of 43.3% in Jordan, [2] reported 14.8% in India; [3, 4] reported 17.8 and 21.6% in Iran, respectively. Furthermore, our rates of associated malformations were even lower than those reported from Europe (29–59.2%) [13, 15, 21] and Latin America (31.4–48.4%) [5, 8].…”

Section: Discussioncontrasting

confidence: 81%

Congenital malformations and medical conditions associated with orofacial clefts in children in Burkina Faso

et al. 2017

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BackgroundOrofacial clefts are usually isolated cases but can be associated with other congenital malformations that are either recognised or unrecognised syndromes. The reported prevalence and pattern of such associated malformations, however, vary among studies. Objectives: To assess the frequencies and aetiologies of congenital malformations and associated medical conditions in children with orofacial clefts in Burkina Faso (Western Africa).MethodsA retrospective descriptive study was carried out at the El Fateh-Suka Clinic in Ouagadougou, Burkina Faso. All children who attended surgery for the repair of a cleft lip and/or palate were included in this study.ResultsThe frequency of congenital malformations associated with cleft lip and/or palate was 39/185 (21.1%). In the group with multiple congenital malformations of unknown origin (34 patients; 18.4%), 66.7% had cleft lip and palate, followed by isolated cleft lip (27.4%) and isolated cleft palate (5.9%). The digestive system (35.3%), the musculoskeletal system (19.6%), and eye, ear, face, and neck (15.7%) were the most affected systems. In the group of syndromic malformations (five patients; 2.7%), amniotic band syndrome (one patient), Van der Woode syndrome (one patient), Goltz syndrome (one patient), and holoprosencephaly (two patients) were identified. Medical conditions included anaemia (39.4%), infections (9.2%), malnutrition (7.5%), and haemoglobinopathies (4.3%).ConclusionsCongenital malformations and medical co-morbidities were frequent in children with OFCs. Further studies and a National Malformations Registry are needed to improve the comprehension of OFCs in Burkina Faso.

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Section: Discussioncontrasting

confidence: 81%

Congenital malformations and medical conditions associated with orofacial clefts in children in Burkina Faso

et al. 2017

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“…(6) Fonoaudióloga; Professora adjunto do Curso de Fonoaudiologia da Pontifícia Universidade Católica de Minas Gerais -PUC Minas, Belo Horizonte, MG, Brasil; Doutora em Linguística pela Universidade Federal de Minas Gerais. (7) Fonoaudióloga; Professora adjunto do Curso de Fonoaudiologia da Pontifícia Universidade Católica de Minas Gerais -PUC Minas, Belo Horizonte, MG, Brasil; Doutora em Linguística pela Universidade Federal de Minas Gerais.…”

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Levantamento epidemiológico dos pacientes portadores de fissura de lábio e/ou palato de um centro especializado de Belo Horizonte

et al. 2011

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OBJETIVO: traçar o perfil epidemiológico dos pacientes com fissura de lábio e/ou palato de um centro especializado de Belo Horizonte. MÉTODO: os dados referentes ao ano de entrada no centro, tipo de fissura, gênero, cidade de origem e idade foram obtidos de planilha do Excel contendo o cadastro dos pacientes. A análise estatística foi realizada por meio do teste qui-quadrado, com nível de significância de 5%. RESULTADOS: a amostra foi composta por 1.219 pacientes, sendo 593 pacientes cadastrados em 2005, 273 em 2006, 222 em 2007 e 131 em 2008. Da amostra total, 49% apresentavam fissura transforame incisivo, 26% pós-forame, 19% pré-forame, 2% pré e pós-forame e 3% outros tipos de má formação craniofacial. Quanto ao gênero, 54% eram do gênero masculino e 46% do feminino. Quanto à origem, 33% eram moradores de Belo Horizonte, 28% de outras cidades da Região Metropolitana de Belo Horizonte, 38,5% do interior de Minas Gerais e 0,5% de outros Estados. Quanto à idade, esta variou de zero a 64 anos (mediana=6,0), com 40% chegando até três anos, 45,5% entre três e 18 anos e 14,5% acima de 18 anos. Segundo o ano de entrada, em 2005 prevaleceu a faixa de seis a 12 anos (29%) e nos anos seguintes a faixa de até um ano (38%, 36% e 43%). CONCLUSÃO: neste centro, a maior parte dos casos apresenta fissura do tipo transforame, é do gênero masculino, oriunda do interior do estado de Minas Gerais e formada por bebês e crianças.

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“…Also, a prevalence of 1.016 per 1000 live births was reported in Hamadan, which is in the northwest of Iran. 10 In Tehran, the capital of Iran, the overall incidence of CL/P between 1998 and 2005 was reported as 2.14 per 1000 live births. 11 Moreover, a prevalence of 0.97 and 0.80 per thousand live births was reported in the north and southwest of Iran, respectively.…”

Section: Discussionmentioning

confidence: 99%

Had Prevalence of Cleft Lip and Palate Differed During the Iran-Iraq War?

Jahanbin

Kianifar²,

Yaghoubi-al³

et al. 2013

Journal of Craniofacial Surgery

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Cleft lip and palate are among the most common congenital defects with multifactorial etiology, and maternal stress may have a role in the development of the malformation; thus, the aim of this study was to explore the role of war on cleft lip and palate (CL/P) prevalence.In this study, records of 101,435 newborn infants delivered in the teaching hospitals of Mashhad and Ahwaz during wartime (1982-1987) and recent years (2005-2010) were reviewed. Samples were analyzed for prevalence of anomaly in both cities at 2 time intervals as well as some related factors; χ and t tests were used for data analysis.Results showed the incidences of CL/P in Mashhad during 1982 to 1987 and 2005 to 2010 were 2 and 2.2 per 1000 live births, respectively; however, its incidence in Ahwaz was 1 per 1000 during wartime and 0.7 per 1000 live births for recent years.Despite significant differences that were found in the prevalence of both cities in recent years (P = 0.001), no significant differences were observed during wartime (P = 0.28).The results revealed that CL/P was more prevalent in both cities, but in contrast to Ahwaz, cleft lip was more prevalent than isolated cleft palate in Mashhad, and significant differences were found between both cities (P = 0.007).The study concluded that the prevalence of CL/P in Ahwaz decreased after the war. However, in Mashhad, its prevalence, which was not affected during wartime, gradually increased. Thus, genetic research may be necessary to establish a genetic predisposition in northeast Iran.

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An Epidemiologic Study of Orofacial Clefts in Hamedan City, Iran: A 15-Year Study

Cited by 25 publications

References 48 publications

Congenital malformations and medical conditions associated with orofacial clefts in children in Burkina Faso

Congenital malformations and medical conditions associated with orofacial clefts in children in Burkina Faso

Levantamento epidemiológico dos pacientes portadores de fissura de lábio e/ou palato de um centro especializado de Belo Horizonte

Had Prevalence of Cleft Lip and Palate Differed During the Iran-Iraq War?

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