Cleanliness and erosion of root canal walls after irrigation with a new HEDP-based solution vs. traditional sodium hypochlorite followed by EDTA. A scanning electron microscope study

Kfir, Anda; Goldenberg, Chen; Metzger, Zvi; Hülsmann, Michael; Baxter, Steffi

doi:10.1007/s00784-020-03249-w

Cited by 24 publications

(52 citation statements)

References 31 publications

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“…Dual Rinse HEDP – NaOCl mixtures were prepared freshly by adding a capsule of Dual Rinse HEDP into 10 ml of 1% NaOCl solution and stirring the solution for a minute. As the mixture is not storable for a long time 15 , 21 ; immediately after the preparation, each 10 ml mixture were divided equally into two syringes and used for two specimens. After the removal of calcium hydroxide procedures, all canals were rinsed with 5 ml of distilled water with a 30-gauge needle and dried with sterile paper points.…”

Section: Methodsmentioning

confidence: 99%

“… 11 , 12 Smear layer can also be reduced using this agent. 13 , 14 , 15 Furthermore, studies have shown that this mixture can enhance the adhesion of some type of cements to the root canal dentin. 16 , 17 , 18 , 19 This combination can be used to remove Ca(OH) 2 dressing and get a clean root canal system as well considering the recommendation of the manufacturer.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of different irrigation solutions and activation methods on removing calcium hydroxide

Harzivartyan

Hazar

Kartal

et al. 2021

Journal of Dental Sciences

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Background/purpose Dual Rinse HEDP is a soft chelator which can be used simultaneously with sodium hypochlorite (NaOCl). The aim of this study is to evaluate the efficacy of Dual Rinse HEDP with different irrigation systems on removing calcium hydroxide [Ca(OH) 2 ]. Materials and methods Eighty maxillary central incisor teeth were shaped and a standard groove on the apical third of the root canal surface was prepared. The root canals were filled with Ca(OH) 2 . Samples were divided into two groups according to the solution and these two groups were divided into three subgroups based on the activation technique. In group 1 (n = 10) Ca(OH) 2 was removed using conventional irrigation with NaOCl whereas in group 2 (n = 10) conventional irrigation with NaOCl – Dual Rinse HEDP mixture was used. Group 3 (n = 15) and group 4 (n = 15) received sonic activation with the same irrigants as groups 1 and 2 respectively. In group 5 (n = 15) passive ultrasonic irrigation (PUI) was used with NaOCl while in group 6 (n = 15) the irrigant was the mixture. The amount of remaining Ca(OH) 2 in the artificial grooves were evaluated under a light microscope. Results None of the procedures managed to completely remove the Ca(OH) 2 from artificial grooves. There was no significant difference between the groups (p = 0.053). The scores were significantly lower in PUI group compared to the other techniques between NaOCl groups (p = 0.021). Conclusion Dual Rinse HEDP does not make a difference on elimination of Ca(OH) 2 . PUI is more efficient than both methods when NaOCl solution is used.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of different irrigation solutions and activation methods on removing calcium hydroxide

Harzivartyan

Hazar

Kartal

et al. 2021

Journal of Dental Sciences

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“…From Kfir et al (2020) – “The SEM images of each section, taken with ×1,000 magnification, were examined and scored for the presence of erosion/etching using the three grade scoring system proposed by Kaya et al score 1: no or minimal erosion (all tubules look normal in appearance and size), score 2: moderate etching/erosion (peritubular dentine is eroded), and score 3: severe etching/erosion”.…”

Section: The Prile 2021 Explanation and Elaboration Documentmentioning

confidence: 99%

PRILE 2021 guidelines for reporting laboratory studies in Endodontology: explanation and elaboration

et al. 2021

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Guidance to authors is needed to prevent their waste of talent, time and resources in writing manuscripts that will never be published in the highest‐quality journals. Laboratory studies are probably the most common type of endodontic research projects because they make up the majority of manuscripts submitted for publication. Unfortunately, most of these manuscripts fail the peer‐review process, primarily due to critical flaws in the reporting of the methods and results. Here, in order to guide authors, the Preferred Reporting Items for study Designs in Endodontology (PRIDE) team developed new reporting guidelines for laboratory‐based studies: the Preferred Reporting Items for Laboratory studies in Endodontology (PRILE) 2021 guidelines. The PRILE 2021 guidelines were developed exclusively for the area of Endodontology by integrating and adapting the modified CONSORT checklist of items for reporting in vitro studies of dental materials and the Clinical and Laboratory Images in Publications (CLIP) principles. The process of developing the PRILE 2021 guidelines followed the recommendations of the Guidance for Developers of Health Research Reporting Guidelines. The aim of the current document is to provide authors with an explanation for each of the items in the PRILE 2021 checklist and flowchart with examples from the literature, and to provide advice from peer‐reviewers and editors about how to solve each problem in manuscripts prior to their peer‐review. The Preferred Reporting Items for study Designs in Endodontology (PRIDE) website (http://pride-endodonticguidelines.org/prile/) provides a link to the PRILE 2021 explanation and elaboration document as well as to the checklist and flowchart.

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“…This enables clinicians to apply “continuous chelation” in the root canal system during the instrumentation phase and throughout the treatment session. The purported advantage of that is that only one irrigant is necessary for root canal cleaning and disinfection, and irrigation time can be shortened to achieve similar results [ 13 , 14 ]. Moreover, in the continuous chelation approach, the root canal wall is ideally conditioned for adhesive root filling materials, as the canal walls remain free of smear layer, yet the exposed collagen fibrils are still calcified [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

“…It would appear that an ultrasonically activated combined NaOCl & HEDP solution maintains its antibacterial effect [19,20]. However, ultrasonic activation invariably results in an increased temperature of the irrigant in the root canal [21] and may also be hampered by the altered physical features of a combined NaOCl & HEDP solution [14,17]. Moreover, the so-called "sonochemical" effects of NaOCl, i.e., the expediting of chemical reactions in aqueous solution by ultrasound, albeit somewhat enigmatic [22,23], may be linked to increased local temperature in cavitation bubbles [24].…”

Section: Introductionmentioning

confidence: 99%

Influence of 1-Hydroxyethylidene-1,1-Diphosphonic Acid on the Soft Tissue-Dissolving and Gelatinolytic Effect of Ultrasonically Activated Sodium Hypochlorite in Simulated Endodontic Environments

et al. 2021

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The addition of Dual Rinse HEDP, an etidronate powder, to a sodium hypochlorite (NaOCl) solution can create a combined single endodontic irrigant with a soft tissue-dissolving and a decalcifying effect, which can replace traditional alternating irrigation with chemically non-compatible solutions. While the short-term compatibility between NaOCl and 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) has been shown, it remains unclear whether ultrasonic activation of a combined NaOCl & HEDP solution immediately reduces the available chlorine and/or renders the NaOCl ineffective in dissolving organic tissue remnants. This was tested in three experiments: (1) direct activation in test tubes in an ultrasonic bath and then the activation by an ultrasonically oscillating tip (IrriSafe) in (2) an epoxy resin model containing a simulated isthmus filled with gelatin, and (3) extracted teeth with simulated resorption cavities filled with soft tissue. The control solutions were physiological saline and 2.5% NaOCl without HEDP. In (1), available chlorine after 30 s of ultrasonic activation (37 kHz) of test and control solution was assessed, as well as shrimp tissue weight loss in direct exposure. In (2) and (3), the ultrasonic tip was driven at 1/3 of full power using the respective unit, and areas of removed gelatin from the isthmus and tissue weight loss were used as the outcomes, respectively. Experiment (1) revealed no negative impact by HEDP on available chlorine (1), while all three experiments showed a highly significant (p > 0.001) synergistic effect, which was not hampered by HEDP, between NaOCl and ultrasonic activation regarding tissue weight loss (1, 3) and dissolution of gelatin (2).

show abstract

Cleanliness and erosion of root canal walls after irrigation with a new HEDP-based solution vs. traditional sodium hypochlorite followed by EDTA. A scanning electron microscope study

Cited by 24 publications

References 31 publications

Evaluation of different irrigation solutions and activation methods on removing calcium hydroxide

Evaluation of different irrigation solutions and activation methods on removing calcium hydroxide

PRILE 2021 guidelines for reporting laboratory studies in Endodontology: explanation and elaboration

Influence of 1-Hydroxyethylidene-1,1-Diphosphonic Acid on the Soft Tissue-Dissolving and Gelatinolytic Effect of Ultrasonically Activated Sodium Hypochlorite in Simulated Endodontic Environments

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