In this transformation era, that humans be able to become competitive subjects to innovate in every single area. The disruption era that grows along with the industrial revolution 4.0 were called digitalization was brought many effects for its changing. As the agent of change, the learner should be able to face it wisely. The student should improve themselves with many competencies and skills. The aim of this review is to encourage the student insight and views about innovative strategies for being an active learner to fulfill the demands of society needs. This paper is based on a systematic literature review. It has collected some related article from JSTOR database, and at the process of article reduction, it has examined and found about 3 articles related to in five periods from 2013-2018. Based on the strategy revealed in the articles, every learner should equip themselves with strong knowledge about regulation, competency, and skills for developing the skills and mindset for dealing with the challenge in this era of disruption. After discussing the main concept of learner strategy for facing the era of disruption, this study finds some strategies should be present for understanding the learner. The most important things for increasing the competency are digital technology skill and foreign language mastership to encourage themselves and integrate the sciences in real implementation. The findings of this review are expected to be useful both learner and education practitioner for gaining insight to further research and successful educational reform.