volume 10, issue 4, P833-852 2018
DOI: 10.18632/aging.101437
View full text

Abstract: Circular RNAs (circRNAs) are a novel type of non-coding RNA expressed across different species and tissues. At present, little is known about the expression and function of circRNAs in the tree shrew brain. In this study, we used RNA-seq to identify 35,007 circRNAs in hippocampus and cerebellum samples from infant (aged 47–52 days), young (aged 15–18 months), and old (aged 78–86 months) tree shrews. We observed no significant changes in the total circRNA expression profiles in different brain regions over time…

Expand abstract