Research on the anti-dam movement in Brazil provides an opportunity to explore social theory at the intersections of social movement studies (SMS) and science and technology studies (STS) and to develop a Latin American perspective on the relationship. The review essay begins with an analysis from an SMS perspective of structural conditions, such as the opportunity structure, and of the strategies of framing and coalition building. Then the review examines STS perspectives on social movements including scientization and the circulation of knowledge in the public sphere. Likewise, beginning with an STS perspective based on the literature on the politics of design, the study examines SMS perspectives that draw attention to broader design conflicts involving choices for the national energy system, its relationship to different economic sectors, and the democratic governance of energy decision-making and remediation. The study of social movements, science, and technology in Latin America can also lead to perspectives that may be less well recognized in work that focuses mainly on wealthy industrialized countries, such as attention to the lack of autonomy of social fields and the ways in which the state's developmentalist aspirations become linked to social injustice.