Chronic Actinic Dermatitis: An Analysis at a Single Institution over 25 Years

Increased incidence of chronic actinic dermatitis in relation to climate changes and air pollution during the past 15 years in Korea

“…reported demographic data for CAD from 1993 to 2009 and found that 67.5% of the patients with CAD were men . We observed an average age of occurrence of 61.46 years, which is similar to that in other previous reports . There are contributing factors to CAD, such as air temperature, male gender, old age, outdoor activity, and pre‐existing conditions .…”

Photosensitive atopic dermatitis – a neglected subset: Clinical, laboratory, histological and photobiological workup

“…The pathogenesis of CAD is unknown; one proposed hypothesis suggests a photo‐induced delayed‐type hypersensitivity reaction to endogenous antigens . Although it is mainly a disease of older men, this entity has been described in young patients as well . A minority of the patients diagnosed with CAD have been described to have an atopic background.…”

Photodermatoses in skin of colour

“…Epidemiology Chronic actinic dermatitis is a persistent dermatitis that most frequently presents within the fourth through sixth decade of life. 5,7,11,[23][24][25][26][27][28] In Caucasians and Asians, there is a male predominance; however, in blacks, there is a female predominance. 5,11,23,25,27,28 While CAD can present in all skin phototypes, there is a tendency towards phototypes V and VI.…”

“…5,7,11,[23][24][25][26][27][28] In Caucasians and Asians, there is a male predominance; however, in blacks, there is a female predominance. 5,11,23,25,27,28 While CAD can present in all skin phototypes, there is a tendency towards phototypes V and VI. 5,20,[24][25][26]29 Pathophysiology The aetiology of CAD reflects a delayed-type hypersensitivity reaction to a photoinduced neoantigen resulting in persistent inflammation.…”