Photodermatoses in skin of colour

Gutiérrez, Daniel; Gaulding, Jewell V.; Beltran, A F Motta; Lim, Henry W.; Pritchett, Ellen

doi:10.1111/jdv.15115

Cited by 14 publications

(11 citation statements)

References 87 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Comprehensive reviews of data from photodiagnostic units in dermatology departments indicate that the photodermatoses most commonly seen are PLE, photoaggravated atopic dermatitis, actinic prurigo, chronic actinic dermatitis, solar urticaria and drug-induced photosensitivity. Photodermatoses occur in dark-skin populations, although with differing frequencies and characteristics from light-skin populations [ 158 ]. In a systematic review of population-based and dermatology outpatient studies of rosacea, a photoaggravated chronic inflammatory facial condition, a global prevalence of up to 5% was estimated; however, studies in which rosacea was self-reported yielded higher prevalence than in those where the condition was determined by examination [ 159 ].…”

Section: Harms Of Exposure To Uv Radiationmentioning

confidence: 99%

The effects of exposure to solar radiation on human health

Neale

Lucas

Byrne

et al. 2023

Photochem Photobiol Sci

View full text Add to dashboard Cite

This assessment by the Environmental Effects Assessment Panel (EEAP) of the Montreal Protocol under the United Nations Environment Programme (UNEP) evaluates the effects of ultraviolet (UV) radiation on human health within the context of the Montreal Protocol and its Amendments. We assess work published since our last comprehensive assessment in 2018. Over the last four years gains have been made in knowledge of the links between sun exposure and health outcomes, mechanisms, and estimates of disease burden, including economic impacts. Of particular note, there is new information about the way in which exposure to UV radiation modulates the immune system, causing both harms and benefits for health. The burden of skin cancer remains high, with many lives lost to melanoma and many more people treated for keratinocyte cancer, but it has been estimated that the Montreal Protocol will prevent 11 million cases of melanoma and 432 million cases of keratinocyte cancer that would otherwise have occurred in the United States in people born between 1890 and 2100. While the incidence of skin cancer continues to rise, rates have stabilised in younger populations in some countries. Mortality has also plateaued, partly due to the use of systemic therapies for advanced disease. However, these therapies are very expensive, contributing to the extremely high economic burden of skin cancer, and emphasising the importance and comparative cost-effectiveness of prevention. Photodermatoses, inflammatory skin conditions induced by exposure to UV radiation, can have a marked detrimental impact on the quality of life of sufferers. More information is emerging about their potential link with commonly used drugs, particularly anti-hypertensives. The eyes are also harmed by over-exposure to UV radiation. The incidence of cataract and pterygium is continuing to rise, and there is now evidence of a link between intraocular melanoma and sun exposure. It has been estimated that the Montreal Protocol will prevent 63 million cases of cataract that would otherwise have occurred in the United States in people born between 1890 and 2100. Despite the clearly established harms, exposure to UV radiation also has benefits for human health. While the best recognised benefit is production of vitamin D, beneficial effects mediated by factors other than vitamin D are emerging. For both sun exposure and vitamin D, there is increasingly convincing evidence of a positive role in diseases related to immune function, including both autoimmune diseases and infection. With its influence on the intensity of UV radiation and global warming, the Montreal Protocol has, and will have, both direct and indirect effects on human health, potentially changing the balance of the risks and benefits of spending time outdoors. Graphical abstract

show abstract

Section: Harms Of Exposure To Uv Radiationmentioning

confidence: 99%

The effects of exposure to solar radiation on human health

Neale

Lucas

Byrne

et al. 2023

Photochem Photobiol Sci

View full text Add to dashboard Cite

show abstract

“…Photodermatoses are generally classified into four categories: immunologicallymediated photodermatoses, chemical and drug-induced photosensitivity, photoexacerbated dermatoses, and genophotodermatoses. [1][2][3] Immunologically-mediated photodermatoses are further sub-divided into five diseases: polymorphous light eruption (PMLE), actinic prurigo (AP), chronic actinic dermatitis (CAD), solar urticaria (SU), and hydroa vacciniforme (HV). The pathophysiology of these diseases is still unclear, but it varies depending on different immune dysregulation.…”

Section: Introductionmentioning

confidence: 99%

“…An example of photodermatoses caused by endogenous agents is porphyrias, which are caused by an abnormal heme biosynthetic pathway. 1,3 Meanwhile, photoexacerbated dermatoses such as photoexacerbated eczema, photoexacerbated atopic dermatitis, systemic lupus erythematosus, autoimmune connective tissue diseases, vesiculobullous diseases, HIV photosensitivity, are the main groups of photodermatoses. 1 Last but not least, genophotodermatoses are rare genetic disorders that cause severe photosensitivity and other manifestations, and examples include xeroderma pigmentosum (XP), Bloom syndrome, and Rothmund-Thomson syndrome.…”

Section: Introductionmentioning

confidence: 99%

“…1,3 Meanwhile, photoexacerbated dermatoses such as photoexacerbated eczema, photoexacerbated atopic dermatitis, systemic lupus erythematosus, autoimmune connective tissue diseases, vesiculobullous diseases, HIV photosensitivity, are the main groups of photodermatoses. 1 Last but not least, genophotodermatoses are rare genetic disorders that cause severe photosensitivity and other manifestations, and examples include xeroderma pigmentosum (XP), Bloom syndrome, and Rothmund-Thomson syndrome. 1,2 To diagnose photodermatoses, the history, clinical presentation, phototesting, and laboratory investigations (e.g.…”

Section: Introductionmentioning

confidence: 99%

“…1 Last but not least, genophotodermatoses are rare genetic disorders that cause severe photosensitivity and other manifestations, and examples include xeroderma pigmentosum (XP), Bloom syndrome, and Rothmund-Thomson syndrome. 1,2 To diagnose photodermatoses, the history, clinical presentation, phototesting, and laboratory investigations (e.g. porphyrins, lupus serology) are necessary in each individual case.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence and Trend of Photodermatoses in Thailand: A 16-year Retrospective Study at Siriraj Hospital

Likittanasombat

Silpa‐archa²,

Chaiyabutr³

et al. 2023

Siriraj Med J

View full text Add to dashboard Cite

Objective: Photodermatoses are a group of cutaneous disorders with abnormal reactions triggered by exposure to sunlight. Previous studies reported varying photodermatoses prevalence in Caucasians and African-Americans; however, it was seldom reported in the Asian population. The aim of our study was to determine the prevalence, clinical characteristics and trend of photodermatoses in Thailand. Materials & Methods: A retrospective chart review was performed at the Faculty of Medicine Siriraj Hospital, Mahidol University using diagnoses from the International Classification of Disease (ICD), Tenth Revisions codes, between January 2005 and September 2021. Results: A total of 561 patients with definite diagnosis of photodermatoses were identified. The prevalence of photodermatoses in the outpatient dermatology clinic was 3 cases per 1,000. The most common photodermatoses was chemical and drug-induced photosensitivity (39.4%), followed by immunologically-mediated photodermatoses (30.1%), photo-aggravated dermatoses (29.4%) and genophotodermatoses (1.1%). Overall phototesting was performed in 276 cases (49.2%). In our study, some photodermatoses had unique clinical characteristics including pinpoint popular variant of polymorphous like eruption and adult-onset actinic prurigo. Over 16 years, the trend of patients being diagnosed with photodermatoses has continued to rise gradually with an increment of 1.67 times. Conclusion: Photodermatoses are uncommon in Thailand. Some photodermatoses have distinctive clinical features in Asian populations. The trend of photodermatoses in Thailand is continually rising, reflecting an increase in physicians’ awareness and knowledge of these cutaneous conditions.

show abstract

Cutaneous Photosensitivity Diseases

Ibbotson

2024

Rook's Textbook of Dermatology

View full text Add to dashboard Cite

The photodermatoses are a diverse group of conditions in which abnormal responses to light exposure are the hallmark. Photodiagnostic investigations through a specialist unit may be essential to ensure accurate diagnosis and management, and this chapter explores the nature of the photodermatoses and the photodiagnostic techniques that can be applied. Management approaches include early diagnosis, prevention and disease suppression, and awareness of the significant adverse impact on well‐being and psychological health that can occur with photosensitivity. Photoprotection is a mainstay approach for the photodermatoses but is often not sufficient alone for disease control. Desensitisation through natural hardening or light‐based therapies may be feasible, although systemic immunosuppressants and immunomodulators may be required. Awareness of the possibility of vitamin D deficiency is also necessary. This chapter will cover these approaches in detail.

show abstract

Photodermatoses in skin of colour

Cited by 14 publications

References 87 publications

The effects of exposure to solar radiation on human health

The effects of exposure to solar radiation on human health

Prevalence and Trend of Photodermatoses in Thailand: A 16-year Retrospective Study at Siriraj Hospital

Cutaneous Photosensitivity Diseases

Contact Info

Product

Resources

About