Chromatographic study of local anaesthetics —basic esters of substituted carbanilic acids

Titrations in nonaqueous solvents

“…Sodium or potassium borohydride could be used to titrate a number of barbiturates in dimethyl sulfoxide and sulfonamides in dimethylformamide (24). Sodium borohydride in aqueous and nonaqueous solutions was used as a titrant for weakly acidic compounds (48).…”

“…The single crystal first-derivative peakto-peak line widths of anisotropic magnetic resonance lines in non-single-crystal substances can be determined accurately North Carolina 28086 from the second-derivative powder spectra (23). A moment method for determining isotropic g values from ESR spectra has been reported (24). The interpretation of an ESR spectrum can sometimes be aided by calculating a significance plot which may be calculated from a digitized ESR spectrum in the same way that a power spectrum may be calculated from a time series (25).…”

Titrations in nonaqueous solvents

“…Sodium borohydride in water was investigated as a strong base titrant for weakly acidic drugs in dimethylformamide and in 2:1 ethanol-chloroform (20,21). Glass or antimony indicating electrodes could be used; visual indicators were also satisfactory.…”