Chondroid syringoma: A diagnosis by fine needle aspiration cytology

Nasit, Jitendra G; Dhruva, Gauravi

doi:10.4103/0974-2077.101404

Cited by 15 publications

(28 citation statements)

References 5 publications

(19 reference statements)

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“…Chondroidsyringoma is a tumor of sweat glands which presents with similar microscopic picture on fine needle aspiration showing biphasic population of cells in fibrillary and chondromy xoidstroma [15]. Since the site of nodular mass in present case is eyelid which also has sweat glands, Chondroidsyringoma forms one of the most important differential of pleo morphic adeno ma of palpabral lobe of lacrimal g land [16]. Therefore, on FNA C, the possibility of present casebeing chondroidsyringoma wasalso considered.…”

Section: Discussionmentioning

confidence: 82%

Pleomorphic adenoma of palpebral lobe of lacrimal gland masquerading as skin adnexal tumor of eyelid

Giriyan

Agrawal

Chandan

2017

Trop J Pathol Microbiol

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Occurrence of Lacrimal gland tumorsis rare. Ben ign epithelial tu mors are more common of which pleomorphic adenoma is commonest. They usually occur in the orbital lobe of lacrimal g land however, they mayrarely occur in palpebral lobe. FNA C helps to rule out other pathologies and narrows the differential diagnosis. We describe a case of young female who presented with a nodular right upper eyelid swelling,clin ically diagnosed as a skin-adnexal tu mor. On FNA C, diagnosis of Chondroidsyringoma of skin adnexawas given. Histopathologically however it was confirmed to be Pleo morphic adenoma of lacrimal gland.Although rare, possibility of both chondroidsyringoma and pleomorphic adenoma of palpebral lobe of lacrimal gland should be considered in case of a mobile, nodular swelling in the upper eyelid. FNA C aids in diagnosis, however,histopathological examination remains the diagnostic gold standard.

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Section: Discussionmentioning

confidence: 82%

Pleomorphic adenoma of palpebral lobe of lacrimal gland masquerading as skin adnexal tumor of eyelid

Giriyan

Agrawal

Chandan

2017

Trop J Pathol Microbiol

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“…5 Diagnosis is confirmed with biopsy of the mass demonstrating nests of cells and ducts surrounded by chondromyxoid stroma. 6 The tumor may arise from eccrine or apocrine sweat glands, with some tumors showing features of both types. 2 The apocrine tumor type is more common and characterized by branching lumina lined by two layers of epithelial cells.…”

Section: Discussionmentioning

confidence: 99%

Giant Chondroid Syringoma of the Lower Eyelid

Hudson

Craven²,

Wojno³

et al. 2017

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Chondroid syringoma is a benign mixed tumor characterized by sweat gland elements in a cartilaginous stroma. This rare tumor accounts for only 0.01% of all primary skin tumors and occurs only rarely in the periorbital region. Chondroid syringomas are usually 0.5 to 3.0 cm in size, with increased risk of malignancy in tumors larger than 3.0 cm. Here we report a rare case of giant chondroid syringoma arising in the lower eyelid, characterized by an epithelial component in a cartilaginous stroma.

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“…CS most commonly presents as a painless, firm, nodular, subcutaneous, or dermal mass of 0.5–3 cm in diameter with a male predilection . CS usually arises in the head and neck region (particularly the cheek, nose, and lip), though cases involving the trunk, extremities, axilla, abdomen, penis, vulva, and scrotal areas have been reported . Clinically, CS is often mistaken for other types of skin lesions such as dermoid cyst, sebaceous cyst, neurofibroma, dermatofibroma, pilomatricoma, lipoma, basal cell carcinoma, and seborrheic keratosis …”

Section: Discussionmentioning

confidence: 99%

“…There are relatively few case reports of CS in the cytology literature as it is rarely encountered in FNA. Though histopathology is a gold standard, FNA has been used for the diagnosis of CS on the basis of thick mucoid aspirates and the biphasic cell population embedded in a variably fibrillary, metachromatic chondromyxoid stroma . However, if the typical epithelial and mesenchymal populations are not represented, with one component predominating, it can lead to diagnostic difficulties and misdiagnoses .…”

Section: Discussionmentioning

confidence: 99%

“…Though histopathology is a gold standard, FNA has been used for the diagnosis of CS on the basis of thick mucoid aspirates and the biphasic cell population embedded in a variably fibrillary, metachromatic chondromyxoid stroma . However, if the typical epithelial and mesenchymal populations are not represented, with one component predominating, it can lead to diagnostic difficulties and misdiagnoses . The differential diagnoses that need to be considered if the biphasic elements are not well differentiated are carcinomas with a mucinous stroma, parenchymal tumors with chondroid areas, and carcinosarcoma .…”

Section: Discussionmentioning

confidence: 99%

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Chondroid syringoma of the axilla: An unusual tumor diagnosed by fine needle aspiration

Rogers

Zhou

Grunes

et al. 2016

Diagnostic Cytopathology

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Chondroid syringoma (CS) is a rare benign adnexal tumor of the skin with a resemblance to pleomorphic adenoma of salivary gland, most commonly involving the head and neck region. In the present literature, reports of the cytologic appearance of CS are scarce as it is rarely encountered by fine needle aspiration (FNA). A 67-year-old woman presented with a 1 year history of a 1 cm subcutaneous nodule in the right axilla. FNA biopsy was performed revealing an epithelial-mesenchymal biphasic neoplasm suggesting CS. Surgical excision confirmed the diagnosis and demonstrated extensive ossification, an extremely rare feature, with only seven reported cases, all located on the head. CS is a rare benign adnexal tumor of the skin, often overlooked due to its unremarkable clinical presentation. FNA is a reliable tool for the diagnosis of CS and helps guide optimal surgical management.

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Chondroid syringoma: A diagnosis by fine needle aspiration cytology

Cited by 15 publications

References 5 publications

Pleomorphic adenoma of palpebral lobe of lacrimal gland masquerading as skin adnexal tumor of eyelid

Pleomorphic adenoma of palpebral lobe of lacrimal gland masquerading as skin adnexal tumor of eyelid

Giant Chondroid Syringoma of the Lower Eyelid

Chondroid syringoma of the axilla: An unusual tumor diagnosed by fine needle aspiration

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