Giant Chondroid Syringoma of the Lower Eyelid

Abstract

Chondroid syringoma is a benign mixed tumor characterized by sweat gland elements in a cartilaginous stroma. This rare tumor accounts for only 0.01% of all primary skin tumors and occurs only rarely in the periorbital region. Chondroid syringomas are usually 0.5 to 3.0 cm in size, with increased risk of malignancy in tumors larger than 3.0 cm. Here we report a rare case of giant chondroid syringoma arising in the lower eyelid, characterized by an epithelial component in a cartilaginous stroma.

Giant chondroid syringoma on the upper lip: a case report

“…Unlike benign lesions, malignant CSs are characterized by local invasion and visceral or bone metastasis. Histopathologically, malignant CSs are characterized by cellular atypia, mitosis, neural and vascular invasion, infiltration into surrounding tissues, and necrosis [12].…”

“…Treatment includes complete excision of the tumor while preserving aesthetic and functional units and follow-up for local recurrence and malignancy. In the case of recurrence, wide excision or Mohs surgery is recommended [2,12].…”

Unusual Lesion of the Eyebrow: A Case Report of Chondroid Syringoma

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Chondroid syringoma is a rare mixed tumor accounting for only 0.01% of all primary skin tumors [1]. Though it's very common occurrence is in head and the neck region, involvement of eyelids is extremely rare [2].

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“…Chondroid syringoma is a skin appendage tumour histopathologically similar to the mixed tumour (pleomorphic adenoma) of the salivary glands [3]. Helwig later classifed this tumor type as chondroid syringoma in 1961 due to the presence of sweat gland elements in a cartilaginous stroma [1]. Incidence of chondroid syringoma is between 0.01% and 0.1% of all skin lesions.…”

“…Chondroid syringomas most commonly occur in the head and neck regions. Only few cases of chondroid syringoma in the periorbital region were reported [1]. Tumors usually range in size from 0.5 cm to 3.0cm and are typically asymptomatic, firm, slow-growing, solitary nodule [3].…”