Cholecystokinin, neuropeptide Y and galanin modulate the release of pancreatic somatostatin-25 and somatostatin- 14 in vitro

Eilertson, Carmen D.; Carneiro, N M; Kittilson, Jeffery D.; Comley, Carolyn; Sheridan, Mark A.

doi:10.1016/0167-0115(96)00027-4

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“…injection of recombinant gNPY inhibited the PSSI gene expression in hypothalamus in vivo. This is somewhat similar to the previous study that the SS-14 release was inhibited by NPY in the trout pancreas in vitro [20]. Up to now, there are scarce reports about the relationship between NPY and PSSI, and additional studies are warranted to elucidate the precise role of NPY on PSSI gene expression.…”

Section: Discussionsupporting

confidence: 86%