1975
DOI: 10.1001/archderm.111.11.1469
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Chlorpromazine photoallergy. Coexistence of immediate and delayed type

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Cited by 36 publications
(19 citation statements)
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“…A photopatch test was carried out with 0.05% chlor promazine in physiological saline solution, because im mediate allergic photosensitivity to chlorpromazine had previously been described [5], 24 It after application of the substance on the back, the test site was uncovered and exposed to black light for 15 min at a distance of 15 cm. Neither immediate nor delayed reactions were observed at the patch test site.…”
Section: Pliotopaich Testingmentioning
confidence: 99%
“…A photopatch test was carried out with 0.05% chlor promazine in physiological saline solution, because im mediate allergic photosensitivity to chlorpromazine had previously been described [5], 24 It after application of the substance on the back, the test site was uncovered and exposed to black light for 15 min at a distance of 15 cm. Neither immediate nor delayed reactions were observed at the patch test site.…”
Section: Pliotopaich Testingmentioning
confidence: 99%
“…It was concluded that the chronic photosensitive dermatitis was due to phenothiazines. phenothiazines; photopatch test; photosensitivityChlorpromazine and other phenothiazines, such as promethazine, perphenazine, thioridazine and levomepromazine, have been widely used as tranquilizers, antipyretics, analgesics and/or antihistamines, and it is known that some of them may produce not only allergic contact dermatitis but also phototoxic and photoallergic reactions (Fisher 1967;Horio 1975;Horio et al 1975). In the present case, photosensitive dermatitis was suspected because the eruptions were limited to sunexposed areas and became aggravated in summer.…”
mentioning
confidence: 79%
“…In the literature, Epstein et al (1957) reported cutaneous photosensitivity caused by these drugs, and presently, phenothiazines are considered to produce not only allergic contact dermatitis (Levan 1957), but phototoxic and photoallergic reactions (Fisher 1967;Horio et al 1975). Immediate allergic photosensitivity due to chlorpromazine was also reported by Horio (1975).…”
Section: Discussionmentioning
confidence: 99%
“…In a few cases an underlying cause (e.g. chlorpromazine) [7] or disease (erythropoetic protopor phyria) [8] can be found. The pathogenesis of SU is not fully understood.…”
Section: Discussionmentioning
confidence: 99%