Chitosan/iota-carrageenan and chitosan/pectin polyelectrolyte multilayer scaffolds with antiadhesive and bactericidal properties

Martins, Alessandro F.; Vlcek, Jessi; Wigmosta, Tara; Hedayati, Mohammadhasan; Reynolds, Melissa M.; Kipper, Matt J.

doi:10.1016/j.apsusc.2019.144282

Cited by 64 publications

(40 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The ideal antimicrobial surface prevents adhesion and growth and has the potential to kill the microbes as well. 171 …”

Section: Antimicrobial Biopolymersmentioning

confidence: 99%

“…Martins et al fabricated layer-by-layer films using iota-carrageenan (CA) or pectin (PC) on chitosan, termed as polyelectrolyte multilayers (PEMs), to test the bactericidal activities against P. aeruginosa and S. aureus . 171 The number of layers with chitosan-terminated ends were between 5 and 15. The WCA of CA-chitosan was 25 ± 0.2° which was low compared to that of PC-chitosan having a value of 51 ± 0.2°.…”

Section: Antimicrobial Biopolymersmentioning

confidence: 99%

See 1 more Smart Citation

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Balasubramaniam

Prateek

Ranjan

et al. 2020

ACS Pharmacol. Transl. Sci.

188

View full text Add to dashboard Cite

The ongoing worldwide pandemic due to COVID-19 has created awareness toward ensuring best practices to avoid the spread of microorganisms. In this regard, the research on creating a surface which destroys or inhibits the adherence of microbial/viral entities has gained renewed interest. Although many research reports are available on the antibacterial materials or coatings, there is a relatively small amount of data available on the use of antiviral materials. However, with more research geared toward this area, new information is being added to the literature every day. The combination of antibacterial and antiviral chemical entities represents a potentially path-breaking intervention to mitigate the spread of disease-causing agents. In this review, we have surveyed antibacterial and antiviral materials of various classes such as small-molecule organics, synthetic and biodegradable polymers, silver, TiO2, and copper-derived chemicals. The surface protection mechanisms of the materials against the pathogen colonies are discussed in detail, which highlights the key differences that could determine the parameters that would govern the future development of advanced antibacterial and antiviral materials and surfaces.

show abstract

“…The ideal antimicrobial surface prevents adhesion and growth and has the potential to kill the microbes as well. 171 …”

Section: Antimicrobial Biopolymersmentioning

confidence: 99%

Section: Antimicrobial Biopolymersmentioning

confidence: 99%

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Balasubramaniam

Prateek

Ranjan

et al. 2020

ACS Pharmacol. Transl. Sci.

188

View full text Add to dashboard Cite

show abstract

“…In this way, films and coatings with hydrophobic surfaces should interact better with the microbial cells, favoring adhesion. Hydrophilic surfaces should prevent the attachment of E. coli cells [ 13 , 14 , 49 , 50 ].…”

Section: Resultsmentioning

confidence: 99%

“…Such an interaction increases the cell membrane permeability, causing evasion of intracellular components, such as nucleic acids and glucose, and preventing the transport of nutrients to the microbial cells. These events promote cell death [ 13 , 51 ]. These results agree with other findings.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Bactericidal Pectin/Chitosan/Glycerol Films for Food Pack Coatings: A Critical Viewpoint

Machado

Facchi

Oliveira

et al. 2020

IJMS

Self Cite

View full text Add to dashboard Cite

Pectin and chitosan films containing glycerol (Gly) at 5, 10, 15, 20, 30, and 40 wt % were prepared in an aqueous HCl solution (0.10 M) by the solvent evaporation method. The unwashed film (UF) containing 40 wt % Gly (UF40) had elongation at break (ε, %) of 19%. Washed films (WFs) had high tensile strength (σ > 46 MPa) and low elongation at break (ε, <5.0%), enabling their use in food packaging applications. The polymers’ self-assembling occurred during the washing, increasing the stiffness. The XPS analysis suggests that some HCl is lost during the drying process, resulting in a low acid content on the UF surfaces. The UF40 (at 5.0 mg/mL) exhibits cytocompatibility toward mammalian cells and antimicrobial and anti-adhesive properties against Escherichia coli. The remaining HCl in the UF40 can be a disadvantage for food packaging applications; the UF40 (∅ = 8.5 mm; 55 μm thickness) releases H3O+/HCl, reducing the pH to approximately 3.0 when kept in 200 mL distilled water for approximately 30 min. Therefore, we propose the use of UF40 to coat commercial food packaging. The UF40 has low permeability to water vapor and oxygen and works as a barrier against ultraviolet light. The UF40 is also colorless and completely transparent. The UF40 maintained tomatoes’ structural integrity for 18 days at room temperature with no oxidation or microorganism contamination. This paper presents a critical viewpoint concerning chitosan-based films with antimicrobial activities.

show abstract

Blood‐Compatible Materials: Vascular Endothelium‐Mimetic Surfaces that Mitigate Multiple Cell‐Material Interactions

Vlcek

Hedayati

Melvin

et al. 2021

Adv Healthcare Materials

Self Cite

View full text Add to dashboard Cite

When flowing whole blood contacts medical device surfaces, the most common blood–material interactions result in coagulation, inflammation, and infection. Many new blood‐contacting biomaterials have been proposed based on strategies that address just one of these common modes of failure. This study proposes to mitigate unfavorable biological reactions that occur with blood‐contacting medical devices by designing multifunctional surfaces, with features optimized to meet multiple performance criteria. These multifunctional surfaces incorporate the release of the small molecule hormone nitric oxide (NO) with surface chemistry and nanotopography that mimic features of the vascular endothelial glycocalyx. These multifunctional surfaces have features that interact with coagulation components, inflammatory cells, and bacterial cells. While a single surface feature alone may not be sufficient to achieve multiple functions, the release of NO from the surfaces along with their modification to mimic the endothelial glycocalyx synergistically improves platelet‐, leukocyte‐, and bacteria‐surface interactions. This work demonstrates that new blood‐compatible materials should be designed with multiple features, to better address the multiple modes of failure of blood‐contacting medical devices.

show abstract

Chitosan/iota-carrageenan and chitosan/pectin polyelectrolyte multilayer scaffolds with antiadhesive and bactericidal properties

Cited by 64 publications

References 61 publications

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Bactericidal Pectin/Chitosan/Glycerol Films for Food Pack Coatings: A Critical Viewpoint

Blood‐Compatible Materials: Vascular Endothelium‐Mimetic Surfaces that Mitigate Multiple Cell‐Material Interactions

Contact Info

Product

Resources

About