Chitosan coated fluorescent mesoporous silica for the sensitive and selective detection of H2O2

Hou, Xinhui; Song, Yifan; Zhou, Hengquan; Guo, Lei; Li, Guiying; Tao, Qian

doi:10.1016/j.saa.2022.121661

Cited by 5 publications

(3 citation statements)

References 40 publications

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“…For example, Hou et al used a concentration diffusion method at room temperature to load 1‐(4‐Aminophenyl)‐1,2,2‐triphenylethene (TPE‐NH 2 ) into the pore channels of preprepared silica. [ 32 ] Since the silica surface usually exhibits negative electrical properties, the AIEgens were stabilized inside the silica by electrostatic interactions. Afterward, the authors coated the nanoparticles with chitosan to prevent AIEgens from leaking.…”

Section: Silica‐based Aie Materialsmentioning

confidence: 99%

“…Hou et al prepared mesoporous silica nanoparticles (MSNs) with a pore size of 2.5 nm and a pore volume of 0.62 cm 3 g −1 , and the AIEgens (TPE‐CS) were loaded into the pores by postloading strategy. [ 32 ] The obtained MSN@TPE‐CS showed strong fluorescence emission, indicating that TPE‐CS was effectively confined into the mesopores. Huang and co‐workers constructed a novel fluorescent silica polymer composite with high fluorescence quantum yield and fluorescence stability via introducing AIEgens into the mesopores of silica through a cationic ring‐opening polymerization, which exhibited strong yellow fluorescence in pure water.…”

Section: Silica‐based Aie Materialsmentioning

confidence: 99%

See 1 more Smart Citation

Inorganic‐Based Aggregation‐Induced Luminescent Materials: Recent Advances and Perspectives

Zhang,

Huang,

Miao

et al. 2023

Small Structures

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Luminogens with aggregation‐induced emission properties (AIEgens), as a novel and attractive fluorescent molecule, have been used in various fields, such as detection, imaging, and disease treatment, which can overcome the traditional aggregation‐caused quenching of organic fluorescent molecules. Nevertheless, AIEgens still have the problems of water solubility and fluorescence stability in practical applications. Aiming for improving the AIEgens’ performance and promoting the development of diverse applications of AIEgens, it is an available strategy to bind AIEgens to those inorganic materials with abundant variety, easy synthesis, and a unique rigid pore structure. The constructed inorganic‐based AIE materials not only inherit the unique luminescence characteristics of AIEgens, but also retain the biocompatibility and degradability of inorganic materials, endowing AIEgens with more attractive versatility. Herein, the up‐to‐date researches of several representative inorganic‐based AIE materials are introduced, with emphasis on their structure design, synthesis strategy, regulation of fluorescence properties of AIE, and their application in the biological field. Finally, the current situation, challenges, and future development potential of inorganic‐based AIE materials are discussed and prospected.

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Section: Silica‐based Aie Materialsmentioning

confidence: 99%

Section: Silica‐based Aie Materialsmentioning

confidence: 99%

Inorganic‐Based Aggregation‐Induced Luminescent Materials: Recent Advances and Perspectives

Zhang,

Huang,

Miao

et al. 2023

Small Structures

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“…Typically, drug-carrying systems tend to modify MSNs with synthetic or biopolymers with good biocompatibility and stability. Herein, we focused our attention on the biomass material chitosan [21,22].…”

Section: Introductionmentioning

confidence: 99%

Construction of mesoporous silica nanodrug delivery system using chitooligosaccharide (CHO) for irinotecan delivery

Fan,

Song,

Liu

et al. 2024

Preprint

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In this study, mesoporous silica nanoparticles (MSNs) around of 50 nm with high specific surface area and pore volume were synthesized using chitooligosaccharide (CHO) as a template. The specific surface area and total pore volume of the as-synthesized MSNs is 1,443.7 m2g-1 and 2.17 cm3g-1, respectively. The anticancer drug irinotecan (CPT-11) was then efficiently loaded onto the MSNs. The surface of the drug loaded MSNs was further modified by the folic acid conjugated chitosan layer to enhance theirs target ability. The outside chitosan layers were very stable under neutral conditions, which can effectively prevent drug leakage. However, the outside chitosan layers are sensitive to pH conditions, which can be rapidly disassemble under acidic conditions. In vitro tests on folic acid conjugated chitosan modified MSNs loaded with CPT-11 against human breast cancer cell (MDA-MB-231) confirmed that folate receptor-mediated endocytosis successfully enhanced the cellular uptake of the MSNs and significantly improved CPT-11 control release process against cancer cells.

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A biocompatible chitosan-based fluorescent polymer for efficient H2O2 detection in living cells and water samples

Sun,

Xu,

Ren

et al. 2024

International Journal of Biological Macromolecules

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Chitosan coated fluorescent mesoporous silica for the sensitive and selective detection of H2O2

Cited by 5 publications

References 40 publications

Inorganic‐Based Aggregation‐Induced Luminescent Materials: Recent Advances and Perspectives

Inorganic‐Based Aggregation‐Induced Luminescent Materials: Recent Advances and Perspectives

Construction of mesoporous silica nanodrug delivery system using chitooligosaccharide (CHO) for irinotecan delivery

A biocompatible chitosan-based fluorescent polymer for efficient H2O2 detection in living cells and water samples

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