Chitosan-based polyherbal toothpaste: As novel oral hygiene product

Mohire, Nitin Chandrakant; Yadav, Adhikrao Vyankatrao

doi:10.4103/0970-9290.70808

Cited by 72 publications

(46 citation statements)

References 6 publications

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“…Silva et al (9) found that the hydroalcoholic extract of Rosmarinus officinalis was effective against oral plankton bacteria (S. mitis, S. sanguinis, S. mutans, S. sobrinus and L. casei), involved in the formation of oral biofilm. The scope of phytotherapy using medicinal plants is vast, involving diverse purposes, including use in oral healthcare (10).…”

Section: Introductionmentioning

confidence: 99%

Dentifrice Containing Extract of Rosmarinus officinalis Linn.: An Antimicrobial Evaluation

et al. 2016

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This study aimed to evaluate the antimicrobial activity of a dentifrice containing an alcoholic extract of rosemary on oral bacteria, compared to a commercially available herbal dentifrice. Standard strains of Streptococcus mutans (ATCC 25175), Streptococcus oralis (ATCC 9811) and Lactobacillus rhamnosus (ATCC 7469) were used, as well as different toothpastes based on rosemary (TR), on propolis (TH), triclosan (positive control) (TPC) and non-fluoridated dentifrice (negative control) (TNC). Bacteria were seeded in Petri dishes and paper discs soaked with dilutions of dentifrice placed on the plates. The inhibition halos were analyzed. It was observed that TR did not show statistical difference in relation to the TH to inhibit S. mutans and S. oralis, while TH was more active against L. rhamnosus. The toothpaste containing rosemary extract had the ability to inhibit the growth of S. mutans, S. oralis and L. rhamnosus, revealing an antimicrobial activity similar to commercially available toothpastes for inhibition of S. mutans and S. oralis.

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Section: Introductionmentioning

confidence: 99%

Dentifrice Containing Extract of Rosmarinus officinalis Linn.: An Antimicrobial Evaluation

et al. 2016

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“…Some researcher also stated that chitosan can be used effectively in dentifrices to improve oral hygiene, since it reduces plaque by 70%. 14 Uraz et al, 15 through a randomized clinical trial, evaluated clinical and microbiological role of chitosan on dental plaque and found decrease in microbiological count (S. mutans and C. albicans levels) in CH and chitosan groups. Chen and Chung 16 evaluated the antibacterial role of chitosan in an in vivo and in vitro method at different temperatures (25-37°C) and pH values (pH 5-8).…”

Section: Discussionmentioning

confidence: 99%

Clinicomicrobiological Evaluation of 2% Chitosan Mouthwashes on Dental Plaque

Mhaske¹,

Ambiti

Jagga

et al. 2018

The Journal of Contemporary Dental Practice

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Aim: This study was conducted to evaluate microbiological and clinical effects of a chitosan chlorhexidine (CH) mouthrinse on plaque control. Materials and methods:Subjects were divided into three groups. Group I included 15 subjects who used 0.2% chlorhexidine digluconate (CHX), group II included 15 subjects who used 2% chitosan (CH) solution, and group III involves 15 subjects who used 0.2% chlorhexidine/2% CH combination. Plaque index (PI), gingival index (GI), and probing depth (PD) were recorded at the baseline, on day 0, and after 4 days. Supragingival plaque samples were subjected for microbiological evaluation. Statistical analysis was done using statistical software IBM Statistical Package for the Social Sciences (SPSS), version 21. Results:Plaque index was lowest in group I at day 0, while it was highest in group III. At day 4, PI was highest in group II, while lowest in group III. Gingival index was lowest in group I and highest in group II at day 0, and lowest in group I and highest in group III at day 4. There was no statistical difference in Streptococcus mutans (S. mutans) Conclusion:Both chitosan and CH were found to be effective in controlling plaque. However, a combination of both provides even better results.Clinical significance: The present study showed that chitosan can be used as an antiplaque agent.

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“…Effect should not be limited in time and mechanical, chemical and aesthetic properties of material may not deteriorate. 25,26 Chitosan as a natural carbohydrated biopolymer with a unique structure and properties, may fulfill the criteria described above. Chitin and chitosan have been investigated as antimicrobial agents against a broad range of target microorganisms such as algae, bacteria, yeasts and fungi in vivo and in vitro experiments involving chitosan in various forms (solutions, films and composites).…”

Section: Bioactivitymentioning

confidence: 99%

Chitosan-Properties and Applications in Dentistry

Kmiec

Pighinelli

et al. 2017

ATROA

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Chitosan is a biopolymer that has a large wound management application and biological proprieties, helping the organisms with fast healing, stimulates the cell proliferation including bacteriostatic and fungistatic particularly useful for wound treatment and as a support material to tissue engineering. The possibilities of application of chitosan are so huge and fascinating as well as not quite discovered. Proprieties of chitosan like biocompatibility, anti inflammatory and others could give promising results in periodontal care or wound healing after teeth extractions. The aim of this work is to review possible applications of chitosan in dentistry area.Keywords: chitosan, biomedical, bioengineering materials, biodegrability, selective permeability, polyelectrolyte action, natural polysaccharide Advances in Tissue Engineering and Regenerative Medicine Research Article Open AccessChitosan-properties and applications in dentistry by 12 Since then several researches with interests in the applications of chitin and aiming to broaden the knowledge about the structural relations and properties of this polysaccharide and its derivatives. 13 Chitosan is a straight chain, cationic polysaccharide that occurs naturally or can be obtained by deacetylation of chitin. Even though there is no nomenclature that definitively guarantees a difference between chitin and chitosan, the term chitosan usually represents cationic copolymers consisting of 2-amino-2-deoxy-β-D-glucose (60-100%) and 2-acetamino -2-deoxy-β-D-glucoside (0-50%), bound together by ß (1→4) bonds. [14][15][16][17] Chitosan is the main derivative of chitin deacetylation in which the mean degree of deacetylation representing the percentage of free NH 2 groups is greater than 60%. 18,19 The average degree of acetylation of chitosan is a measure of the average number of 2-acetamide-2-dexosi-D-glucopyranose and 2-amino-2-deoxy-D-glucopyranose units. The relative percentage of these units has a direct influence on the solubility of chitosan and is an important parameter to determine the average degree of acetylation or indirectly the average degree of deacetylation, which in this way represents the concentration of amino groups, besides exerting a great influence on the physical properties, chemical and biological. 11The amino groups of chitosan are more reactive with respect to the acetamido groups of chitin. The free electron pair of nitrogen in the amino groups is responsible for the adsorption of metallic cations. The average degree of deacetylation determines the fraction of amino groups that are available for interaction with metals. The protonation of amino groups in acid solutions is responsible for the electrostatic attraction of anions. 14 Unlike chitin, chitosan is soluble in dilute acid medium forming a cationic polymer that confers special properties differentiated with respect to the vegetal fibers.11 Chitosan is soluble in dilute acids, such as acetic acid, formic acid, lactic acid, as well as inorganic acids, after prolonged agitation. However,...

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Chitosan-based polyherbal toothpaste: As novel oral hygiene product

Cited by 72 publications

References 6 publications

Dentifrice Containing Extract of Rosmarinus officinalis Linn.: An Antimicrobial Evaluation

Dentifrice Containing Extract of Rosmarinus officinalis Linn.: An Antimicrobial Evaluation

Clinicomicrobiological Evaluation of 2% Chitosan Mouthwashes on Dental Plaque

Chitosan-Properties and Applications in Dentistry

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