Chiral metal–organic framework used as stationary phases for capillary electrochromatography

Fei, Zhi-Xin; Mei, Zhang; Zhang, Junhui; Yuan, Liming

doi:10.1016/j.aca.2014.04.054

Cited by 86 publications

(52 citation statements)

References 48 publications

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“…A few applications of MOFs as stationary phases for CEC analysis are listed in Table . Fei and co‐workers utilized a homochiral MOF material [Zn 2 (D‐cam)(4,4′‐bpy)] n (D‐cam = D‐(+)‐camphoric acid, 4,4′‐bpy = 4,4′‐bipyridine) as the chiral stationary phase for OT capillary electrochromatography (OT‐CEC). In this work, sodium silicate solution (Na 2 SiO 3 ) was utilized to modify the inner wall of the capillary and to obtain a stable layer as the stationary phase, providing sufficient space for the incorporation of MOFs.…”

Section: Application Of Mofs As Chromatographic Stationary Phasesmentioning

confidence: 99%

Recent advances in metal‐organic frameworks and covalent organic frameworks for sample preparation and chromatographic analysis

Wang

2017

Electrophoresis

102

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In the field of analytical chemistry, sample preparation and chromatographic separation are two core procedures. The means by which to improve the sensitivity, selectivity and detection limit of a method have become a topic of great interest. Recently, porous organic frameworks, such as metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), have been widely used in this research area because of their special features, and different methods have been developed. This review summarizes the applications of MOFs and COFs in sample preparation and chromatographic stationary phases. The MOF- or COF-based solid-phase extraction (SPE), solid-phase microextraction (SPME), gas chromatography (GC), high-performance liquid chromatography (HPLC) and capillary electrochromatography (CEC) methods are described. The excellent properties of MOFs and COFs have resulted in intense interest in exploring their performance and mechanisms for sample preparation and chromatographic separation.

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Section: Application Of Mofs As Chromatographic Stationary Phasesmentioning

confidence: 99%

Recent advances in metal‐organic frameworks and covalent organic frameworks for sample preparation and chromatographic analysis

Wang

2017

Electrophoresis

102

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“…Thus, rinsing with solutions containing the coating after several run cycles is needed to “regenerate” these types of coatings. In this manner, Fei and coworkers have used a homochiral helical MOF postcoated onto a sodium silicate layer that was bound to the silanol groups of the capillary wall by a dehydration procedure. Stavrou and coworkers have prepared a cellulose‐based SP with the aid of an ionic liquid .…”

Section: Preparation Approaches For Ot‐cec Coatingsmentioning

confidence: 99%

“…MOFs derived from enantiomerically pure building blocks can be assembled to form homochiral 3D frameworks where chiral recognition is believed to occur. Fei and coworkers have used d ‐camphoric acid whilst Pan and coworkers have used l ‐alanine as such building blocks.…”

Section: Modes Of Separationmentioning

confidence: 99%

Open tubular‐capillary electrochromatography: Developments and applications from 2013 to 2015

et al. 2016

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Open tubular CEC (OT-CEC) separates analyte mixtures by a combination of electrophoretic, electro-osmotic, and/or chromatographic effects. OT-CEC research is an active and growing field, with studies encompassing a wide range of investigations related to new strategies for chemical modification of the inner surface of the capillary, leading to the introduction of novel stationary phase coatings. This review has examined the literature on OT-CEC from 2013 to August 2015 and highlights the developments in the fabrication of highly selective stationary phases, based on materials that include cyclodextrin chiral selectors, graphene and graphene oxide, metal-organic frameworks, molecularly imprinted polymers, nanoparticles, nanolatex particles, nanocomposites, in situ generated polymers, block polymers, tentacle-type polymers, polyelectrolyte multilayers, polysaccharides, phospholipids, and proteins. This review, while considering the development of novel OT-CEC coating materials, specifically examines different immobilization or coating methodologies and approaches and also discusses the separation mechanisms that occur with these new materials. These OT-CEC coatings are intended mainly to separate low molecular weight molecules relevant to the pharmaceutical, agricultural, and food industries as well as for use in environmental monitoring.

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“…For instance, Fei et al. reported the first example of using an MOF [Zn 2 (D‐Cam) 2 (4,4′‐bby)] n (D‐Cam = D‐(+)‐camphoric acid, 4,4′‐bby = 4,4′‐bipyridine) as CSP for separation of chiral compounds. The MOF was coated to a capillary which was pre‐treated by sodium silicate to granulate the inner wall and obtain a stable stationary phase particles layer.…”

Section: Applications Of Nps and Monoliths In Cec And Miniaturised Chmentioning

confidence: 99%

Approaches for enantioselective resolution of pharmaceuticals by miniaturised separation techniques with new chiral phases based on nanoparticles and monolithis

et al. 2016

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This article discusses new developments in the preparation of nanoparticles and monoliths with emphasis upon their application as the stationary and pseudo-stationary phases for miniaturised liquid phase separation techniques, which have occurred in the last 10 years (from 2006 to the actuality). References included in this review represent current trends and state of the art in the application of these materials to the analysis, by EKC, CEC and miniaturised chromatography, of chiral compounds with environmental interest such as pharmaceuticals. Due to their extraordinary properties, columns prepared with these new chiral stationary or pseudo-stationary phases, based on materials such as gold nanoparticles, metal-organic frameworks, ordered mesoporous silicas, carbonaceous materials, polymeric-based and silica-based monoliths or molecularly imprinted materials, can usually show some improvements in the separation selectivity, column efficiency and chemical stability in comparison with conventional chiral columns available commercially.

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Chiral metal–organic framework used as stationary phases for capillary electrochromatography

Cited by 86 publications

References 48 publications

Recent advances in metal‐organic frameworks and covalent organic frameworks for sample preparation and chromatographic analysis

Recent advances in metal‐organic frameworks and covalent organic frameworks for sample preparation and chromatographic analysis

Open tubular‐capillary electrochromatography: Developments and applications from 2013 to 2015

Approaches for enantioselective resolution of pharmaceuticals by miniaturised separation techniques with new chiral phases based on nanoparticles and monolithis

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