Children of depressed and schizophrenic mothers

Grunebaum, Henry; Cohler, Bertram J.; Kauffman, Carol; Gallant, David

doi:10.1007/bf01463553

Cited by 71 publications

(31 citation statements)

References 13 publications

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“…In the two studies in which differences were not found-the Boston (Cohler, Grunebaum, Weiss, Garner, & Gallant, 1977;Herman, Mirsky, Ricks, & Gallant, 1977) and the Danish Birth Cohort (Orvaschel et al, 1979) studies--the relative simplicity of the tasks may account for the negative findings (ErlenmeyerKimling et al, 1982;Nuechterlein, 1983). Versions of the Continuous Performance Test (CPT), a test of sustained visual attention, that produce very few errors in performance do not differentiate well between children of schizophrenics and children of normal parents Cohler et al, 1977;Erlenmeyer-Kimling et al, 1982;Erlenmeyer-Kimling, Kestenbaum, et aI., 1984;Grunebaum, Cohler, Kauffman, & Gallant, 1978;Nuechterlein, 1983), whereas more complex versions appear to work very well in this regard Erlenmeyer-Kimling, Cornblatt,& Golden, 1983;Nuechterlein, 1983;Rutschmann, Cornblatt, & Erlenmeyer-Kimling, 1977). Task parameters, rather than the type of process or sensory modality that the tests tap, appear to determine whether a particular test will successfully distinguish high-risk subjects.…”

Section: Attention and Information Processingmentioning

confidence: 93%

Biobehavioral risk factors in children of schizophrenic parents

Erlenmeyer‐Kimling

Cornblatt

1984

J Autism Dev Disord

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Research on risk factors for schizophrenia is reviewed with emphasis on children of schizophrenic parents. As children of schizophrenic parents are not representative of the majority of individuals who become schizophrenic, examination of variables such as those relating to home environment or parental characteristics in these children is not expected to contribute greatly to an understanding of risk for schizophrenia or to the search for early indicators of a genetic liability, whereas study of selected biobehavioral variables may do so. Four areas of biobehavioral functioning that have been examined in high-risk research are discussed. Three of these are considered to be compatible with the hypothesis of a neurointegrative defect underlying schizophrenia-proneness and to be promising for further research.

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Section: Attention and Information Processingmentioning

confidence: 93%

Biobehavioral risk factors in children of schizophrenic parents

Erlenmeyer‐Kimling

Cornblatt

1984

J Autism Dev Disord

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“…reported deviant cognitive or linguistic development among infants or preschoolers of low-income mothers with depressive symptoms (Coghill, Caplan, Alexandra, Robson, & Kumar, 1986;Goodman, 1987;Grunebaum, Cohler, Kaufman, & Gallant, 1978;Hubbs-Tait, Fusco, Hann, Osofsky, & Hughes, 1992;Lyons-Ruth, Zoll, Connell, & Grunebaum, 1986) as well as among low-income preschoolers with behavior problems (Erickson, Sroufe, & Egeland, 1985).…”

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confidence: 96%

Preschool children at social risk: Chronicity and timing of maternal depressive symptoms and child behavior problems at school and at home

1993

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The current study investigated the relationship between previous, recent, or chronic maternal depressive symptoms and subtypes of child behavior problems rated by teachers and mothers among 64 low-income children aged 4-6 years. Sixty-nine percent of mothers with high depressive symptom levels at the preschool assessment had also reported high symptom levels during the child's infancy. Children whose mothers reported depressive symptoms at both ages exhibited significantly elevated rates of hostile behavior problems in the classroom and at home compared to children of never-depressed mothers. Children of mothers who were previously but not currently depressed showed significantly more anxious and withdrawn behavior at school and at home, while children of recently depressed mothers were more hyperactive and demanding. Child cognitive scores and father absence were also related to behavior problems, but these variables did not mediate the independent effects of chronicity and timing of maternal depressive symptoms on the types of child symptoms displayed.

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“…Some family relatives of affected patients also carry the endophenotype, although not the disorder phenotype (i.e., affective symptoms) in the case of BD (Adida et al, 2012). In fact, some studies also described attention deficits in unaffected relatives of individuals with mood disorders (Bora, Yucel, & Pantelis, 2009;Brotman, Rooney, Skup, Pine, & Leibenluft, 2009;Grunebaum, Cohler, Kauffman, & Gallant, 1978;Klimes-Dougan, Ronsaville, Wiggs, & Martinez, 2006;Zalla et al, 2004). Gottesman, & Gould (2003) discussed endophenotypes and suggested five criteria that should be characteristic of a trait to qualify it as an endophenotype.…”

Section: Discussionmentioning

confidence: 99%

Attention impairment in bipolar disorder: A systematic review.

Camelo

Velasques

Ribeiro

et al. 2013

Psychology & Neuroscience

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Bipolar disorder (BD) has been associated with marked cognitive impairment, including euthymic periods. Attention is among the most compromised functions in BD. Changes related to learning, memory, and visuospatial abilities can be derived from these attention impairments. The objective of this article is to review the scientific literature on the performance of BD patients in attention tests. A systematic review was performed of controlled studies that assessed attention in patients diagnosed with BD aged between 18 and 65 years. The databases included Medline, LILACS, Cochrane Library, Institute for Scientific Information Web of Knowledge, and Scientific Electronic Library Online (SciELO), and the search encompassed the period from 2008 to 2013. Only studies that had a minimum sample of 10 patients were included. A total of 110 articles fulfilled the inclusion criteria. Compared with healthy control subjects, bipolar patients showed poorer attention performance. Compared with other mental disorders, BD was associated with poorer performance than unipolar depression but better performance than schizophrenia. When bipolar patients in different phases of the disease were compared with one another, the performance of euthymic patients was similar to or better than patients in a depressive state; moreover, manic patients performed worse than depressive patients. Attention is significantly impaired in BD. Attention impairment in BD is milder than in schizophrenia but greater than in unipolar depression. Attention impairment is possibly more severe in manic and depressed episodes than in euthymic periods

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Children of depressed and schizophrenic mothers

Cited by 71 publications

References 13 publications

Biobehavioral risk factors in children of schizophrenic parents

Biobehavioral risk factors in children of schizophrenic parents

Preschool children at social risk: Chronicity and timing of maternal depressive symptoms and child behavior problems at school and at home

Attention impairment in bipolar disorder: A systematic review.

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