Child Behavior Checklist Profiles of Children and Adolescents with and at High Risk for Developing Bipolar Disorder

Giles, Lisa; DelBello, Melissa P.; Stanford, Kevin E.; Strakowski, Stephen M.

doi:10.1007/s10578-006-0041-6

Cited by 47 publications

(41 citation statements)

References 15 publications

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“…Biederman and colleagues (Biederman et al , 1996Faraone et al 2005) reported that youngsters who were diagnosed with bipolar disorder (using a semi-structured diagnostic interview) had clinically significant elevations (T-scores [ 70) on the following CBCL subscales: Aggression, Attention Problems, and Anxious/Depressed. This profile has been replicated by other investigators (e.g., Carlson and Kelly 1998;Diler et al 2007;Giles et al 2007;Hazell et al 1999) and meta-analysis showed that this profile differentiated between youngsters diagnosed with bipolar disorder and those with ADHD (Mick et al 2003).…”

Section: Introductionsupporting

confidence: 66%

The CBCL Bipolar Profile and Attention, Mood, and Behavior Dysregulation

2010

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Biederman and colleagues reported that a CBCL profile identified youngsters who were diagnosed with bipolar disorder. Some studies found that this CBCL profile does not reliably identify children who present with bipolar disorder, but nonetheless this CBCL does identify youngsters with severe dysfunction. However, the nature of the impairment of youngsters who fit this profile is unclear. The goal of this study was to describe the clinical characteristics of youngsters who fit this CBCL profile. The sample included 310 youngsters referred to an outpatient psychopharmacology clinic. There were 55 youngsters who fit the CBCL profile. These youngsters were compared to 255 youngsters who did not fit the CBCL profile. Measures included the CBCL, standardized measures of aggression and ADHD symptoms, youngsters’ self-reported depression, DSM-IV diagnoses, and child and adolescent psychiatrists’ ratings of impairment and functioning. Compared to youngsters who did not fit the CBCL bipolar disorder profile, youngsters who fit the profile had significantly higher scores on all but one CBCL scale and significantly higher levels of aggression. Youngsters who fit the CBCL profile also had greater psychosocial impairment and more DSM-IV diagnoses than youngsters who did not fit the profile. Youngsters who fit the CBCL profile exhibit severe dysregulation across multiple domains of functioning including attention, affective, and behavioral dysregulation that are not easily nor efficiently captured by extant DSM-IV diagnoses. These youngsters are not uncommon and comprise slightly less than 1 in 5 referrals to a child psychiatry clinic

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Section: Introductionsupporting

confidence: 66%

The CBCL Bipolar Profile and Attention, Mood, and Behavior Dysregulation

2010

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“…Giles et al 38 verified that bipolar offspring scored significantly higher than healthy controls on the anxious/depressed, attention problems, aggression and withdrawal subscales, and lower than bipolar youth on all scales of the CBCL except for the somatic complaints and anxious/depressed subscales. We found more internalizing symptoms in the YSR than in the CBCL, which is in accordance with the literature.…”

Section: Discussionmentioning

confidence: 99%

The prevalence of psychopathology in offspring of bipolar women from a Brazilian tertiary center

Benetti

Gutt

Krelling

et al. 2009

Rev. Bras. Psiquiatr.

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“…Henin et al (2005) evaluated mental disorders in children of parents with bipolar disorder and concluded that psychiatric disorders such as anxiety, depression, behavioral disorders and social phobias in children of these patients are significantly higher than healthy controls (25). Giles et al (2007) reported that the most frequent mental disorders in children of parents with bipolar disorder are aggressive behaviors, anxiety disorder, depression and attention problems (26). Reichart et al (2004) found similar disorders in subscales of anxiety, depression and aggressive behaviors (10).…”

Section: Discussionmentioning

confidence: 99%

Comparing Mental Health of School-Age Children of Parents With/Without Bipolar Disorders: A Case Control Study

Shamsaei¹,

Cheraghi²,

Dehghani³

et al. 2015

Avicenna J Neuro Psycho Physiology

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Background: Children of parents with bipolar disorder appear to have an increased risk of early-onset Bipolar Disorder (BP), mood disorders and other psychiatric disorders. Objectives: The aim of this study was to compare the mental health of school-age children of parents, with/without bipolar disorder. Materials and Methods: This case-control study included one hundred children aged six to twelve years, who had parents with bipolar disorder and 200 children of 163 demographically-matched control parents. Parents with bipolar disorder were recruited from Farshchian Psychiatric Hospital of Hamadan, Iran, during year 2014. The parent version of the Child Symptom Inventory-4 questionnaire was used to measure mental health. Mean comparisons were performed using Student's t test while effect sizes were estimated by Cohen's d coefficient. The Chi-square test was used to assess significant differences between frequency distribution of demographic variables in both groups. The significance level was considered less than 0.05. Results: There were statistically significant differences between children of parents with and those without bipolar disorder regarding attention deficit hyperactivity disorder, oppositional defiant disorder, conduct, generalized anxiety disorder, schizophrenia, major depression, separation anxiety (P< 0.001) and social phobia (P < 0.05). Children of parents with BP are at high risk for psychiatric disorders. Conclusions: These findings support that the careful evaluation and prospective following of the psychopathology of children of parents with bipolar disorder are critical for early identification and treatment.

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Child Behavior Checklist Profiles of Children and Adolescents with and at High Risk for Developing Bipolar Disorder

Cited by 47 publications

References 15 publications

The CBCL Bipolar Profile and Attention, Mood, and Behavior Dysregulation

The CBCL Bipolar Profile and Attention, Mood, and Behavior Dysregulation

The prevalence of psychopathology in offspring of bipolar women from a Brazilian tertiary center

Comparing Mental Health of School-Age Children of Parents With/Without Bipolar Disorders: A Case Control Study

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