Chikungunya: a reemerging infection spreading during 2010 dengue fever outbreak in National Capital Region of India

Abstract

Chikungunya fever is an important reemerging arbovirus illness, which is transmitted by the same vector as of dengue virus. Many cases of concurrent infections with multiple dengue virus serotypes have been reported in many countries. Also, concurrent infection with Chikungunya virus and dengue virus has been reported in the past in Delhi. Therefore, this study was done to detect Chikungunya IgM antibodies in suspected dengue fever patients. In this study, 1666 serum samples suspected of dengue fever and collected during the outbreak period (August 2010-December 2010) were tested for dengue IgM antibodies, of which 736 tested negative. Of the 736 dengue IgM negative sera, 666 were tested for Chikungunya IgM antibodies. The demographic profile and essential laboratory investigations were recorded. Chikungunya IgM was detected in 9.91 % of the patients. During the post-monsoon period though dengue dominated in numbers, the number of Chikungunya fever cases increased gradually followed by an abrupt decrease with the onset of winter. The Chikungunya IgM positive patients were suffering from fever of more than 5 days duration and had thrombocytopenia. Due to similarity in clinical features and vector transmitting dengue and Chikungunya virus, continuous surveillance of both dengue fever and Chikungunya fever is desirable for better management and epidemiological assessment.

Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border

“…These data are in stark contrast with other studies conducted in the country that have reported the presence of DENV in approximately 30% of patients with febrile syndrome [ 42 ] and a cumulative incidence of cases ranging between 36.5 and 268.7 cases/100,000 inhabitants in different regions of Colombia [ 43 , 44 ]. This low DENV detection rate can be explained by an increase in the number of cases of the other arboviruses studied, as it has been previously reported in India, where the prevalence of DENV decreased with the increase in cases of CHIKV [ 45 , 46 ].…”

Acute undifferentiated fever in India: a multicentre study of aetiology and diagnostic accuracy

“…A large outbreak of Chikungunya was reported in Ahmedabad in India in 2006 [ 22 ]. Sharing the same vector, chikungunya is likely to occur during dengue outbreaks, and in a study during a dengue outbreak in Delhi in 2010, 10% (66/666) positive chikungunya cases were diagnosed among dengue IgM negative fever patients [ 23 ]. Sporadic outbreaks of chikungunya has been reported in India since 1963, in 2006 affecting 13 states with 1.4 million suspected cases [ 23 ], with high numbers in Andhra Pradesh, Tamil Nadu and Maharashtra.…”

“…Sharing the same vector, chikungunya is likely to occur during dengue outbreaks, and in a study during a dengue outbreak in Delhi in 2010, 10% (66/666) positive chikungunya cases were diagnosed among dengue IgM negative fever patients [ 23 ]. Sporadic outbreaks of chikungunya has been reported in India since 1963, in 2006 affecting 13 states with 1.4 million suspected cases [ 23 ], with high numbers in Andhra Pradesh, Tamil Nadu and Maharashtra. This supports the finding in the present study of highest prevalence of chikungunya in Anantapur (Andhra Pradesh), Oddanchatram and Ambur (Tamil Nadu) and Ratnagiri (Maharashtra).…”

Knowledge and Awareness Regarding Chikungunya among Urban Community People of Selected Area of Dhaka City Bangladesh

“…In India, first outbreak occurred in Kolkata in 1963, since then a number of other outbreaks in Maharashtra, Andhra [10]. In 2010, the National Capital Region of India was the seroprevalence rate 9.91% [11]. In 2016, Mumbai reported 12.5% seroprevalence rate [12].…”