Chemistry of compounds associated with endophyte/grass interaction: ergovaline- and ergopeptine-related alkaloids

Garner, G. B.; Rottinghaus, George E.; Cornell, C. N.; Testereci, Haluk

doi:10.1016/0167-8809(93)90039-r

Cited by 76 publications

(54 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4 However, this association is responsible for the production of compounds that are toxic to livestock. 5,6 Ergovaline has been recognized as the main ergopeptine alkaloid produced in tall fescue 7,8 and is considered to be responsible for fescue toxicosis in livestock. 9 Two main diseases were distinguished on the basis of visible symptoms and on the period of the year they were observed.…”

Section: ■ Introductionmentioning

confidence: 99%

Endophyte Infection of Tall Fescue and the Impact of Climatic Factors on Ergovaline Concentrations in Field Crops Cultivated in Southern France

Repussard

Zbib

Tardieu

et al. 2014

J. Agric. Food Chem.

View full text Add to dashboard Cite

Tall fescue (Lolium arundinaceum) infected by Epichloe coenophiala contains ergot alkaloids responsible for fescue toxicosis in Australia, New Zealand, and the United States, with only a few cases occurring in Europe. The detection of Epichloe in 166 L. arundinaceum collected in southern France revealed that 60% were infected, 51% being high ergovaline producers. The ergovaline level in endophyte-infected tall fescue Kentucky 31 was monitored during 3 years in various parts of the plant. Maturation of plants, recorded according to the BBCH scale, appeared to be the main factor for estimating the risk of toxicity. Ergovaline levels of ≥300 μg/kg dry matter were obtained at the end of spring, the beginning of autumn, and mid-winter. Positive correlation between ergovaline level and cumulative degree-d was observed, whereas rainfall had no effect. These results suggest that the lack of fescue toxicosis observed in France cannot be explained by the lack of ergovaline in tall fescue.

show abstract

Section: ■ Introductionmentioning

confidence: 99%

Endophyte Infection of Tall Fescue and the Impact of Climatic Factors on Ergovaline Concentrations in Field Crops Cultivated in Southern France

Repussard

Zbib

Tardieu

et al. 2014

J. Agric. Food Chem.

View full text Add to dashboard Cite

show abstract

“…However, it is unknown which organisms within the rumen microbiome are responsible for the degradation. Tryptophan is essential for the biosynthesis of ergovaline (Garner et al 1993;Roylance et al 1994). The structure of tryptophan allows for the formation of the ergovaline ring structure (Figure 1) which has a similar backbone to several catecholamines, including dopamine and serotonin.…”

Section: B Ergot Alkaloids and Rumen Microbiomementioning

confidence: 99%

Fescue toxicosis and its influence on the rumen microbiome: mitigation of production losses through clover isoflavones

Melchior

Myer

2018

Journal of Applied Animal Research

View full text Add to dashboard Cite

This review highlights concerns with endophyte-infected tall fescue as a primary forage base in the southeastern United States and discusses specific physiological and ruminal effects caused by consumption of ergot alkaloids. Additionally, in an effort to promote various mitigation strategies to abate production limitations caused by fescue toxicosis, this review discusses the use of cool-season legumes, specifically red clover, with the already established forage base. Clovers are often mixed into pastures and help improve animal performance. Clovers contain phytoestrogenic compounds known as isoflavones that may be beneficial in reducing physiological limitations with consumption of endophyte-infected tall fescue. ARTICLE HISTORY

show abstract

“…The involvement of ergopeptine alkaloids produced by the endophyte fungus accounts for the earlier observations that symptoms were similar to ergotism. Ergovaline levels are 5 times or more higher in reproductive heads than in vegetative tissue, and increase with N fertilisation (Garner et al 1993). 'Kentucky 31' pasture grown in trials in New Zealand has ergovaline levels only about one half those measured in local naturalised "roadside" tall fescue (G. A.…”

Section: Endophyte In Tall Fescuementioning

confidence: 99%

“…It is generally accepted that the principal agents of tall fescue toxicity are the ergopeptine alkaloids, notably ergovaline (Garner et al 1993). Loline alkaloids in infected tall fescue (Bush et al 1993) have also received attention.…”

Section: Endophyte In Tall Fescuementioning

confidence: 99%

Tall fescue in Australia and New Zealand

Easton

Lee

Fitzgerald³

1994

New Zealand Journal of Agricultural Research

View full text Add to dashboard Cite

Tall fescue is widely naturalised in Australia and New Zealand. Its use in pastoral agriculture has developed with the availability of suitable cultivars. Naturalised tall fescue is infected with Acremonium endophyte and is known to be toxic. The significance of endophyte is briefly discussed. Tall fescue can be slow to establish after sowing, and palatability is sometimes inadequate. Greatly enhanced winter growth, through the use of Mediterranean germplasm, would extend use of the species into more summer-dry environments. Research supporting these and other objectives is reviewed. Current breeding programmes in Australia and New Zealand are described.

show abstract

Chemistry of compounds associated with endophyte/grass interaction: ergovaline- and ergopeptine-related alkaloids

Cited by 76 publications

References 52 publications

Endophyte Infection of Tall Fescue and the Impact of Climatic Factors on Ergovaline Concentrations in Field Crops Cultivated in Southern France

Endophyte Infection of Tall Fescue and the Impact of Climatic Factors on Ergovaline Concentrations in Field Crops Cultivated in Southern France

Fescue toxicosis and its influence on the rumen microbiome: mitigation of production losses through clover isoflavones

Tall fescue in Australia and New Zealand

Contact Info

Product

Resources

About