ChemInform Abstract: Epoxidation of Alkenes Using HOF·MeCN by a Continuous Flow Process.

Abstract

Oxirane derivatives R 0030 Epoxidation of Alkenes Using HOF·MeCN by a Continuous Flow Process. -The oxidizing agent is generated in situ from fluorine and wet acetonitrile. It reacts with a variety of alkenes in a continuos flow reactor to gives oxiranes in good yields. The method is applicable to large scale synthesis. -(MCPAKE, C. B.; MURRAY, C. B.; SANDFORD*, G.; Tetrahedron Lett. 50 (2009) 15, 1674-1676; Dep. Chem., Univ. Durham, Durham DH1 3LE, UK; Eng.) -Mais 30-100