Chemical structure and inhibition on α-glucosidase of the polysaccharides from Cordyceps militaris with different developmental stages

Wu, Li; Sun, Hao; Hao, Yali; Zheng, Xiaomin; Song, Qi; Dai, Shuhan; Zhu, Zhiwei

doi:10.1016/j.ijbiomac.2020.01.178

Cited by 51 publications

(28 citation statements)

References 52 publications

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“…In the wavelength range of 4000-500 cm −1 (Figure 1c), LPEPS-1 exhibited typical absorption peaks of polysaccharide. The wide and strong absorption peak at 3395 cm −1 was the stretching vibration of the hydroxyl group (-OH) [26]. The strong absorption peak at 2936cm −1 was the stretching vibration of the C-H bond group.…”

Section: Uv and Ft-ir Spectra Analysismentioning

confidence: 99%

Structural Characterization and Antioxidant Activity of Exopolysaccharide from Soybean Whey Fermented by Lacticaseibacillus plantarum 70810

Tian

Mao

Dong

et al. 2021

Foods

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Soybean whey is a high-yield but low-utilization agricultural by-product in China. In this study, soybean whey was used as a substrate of fermentation by Lacticaseibacillus plantarum 70810 strains. An exopolysaccharide (LPEPS-1) was isolated from soybean whey fermentation by L. plantarum 70810 and purified by ion-exchange chromatography. Its preliminary structural characteristics and antioxidant activity were investigated. Results show that LPEPS-1 was composed of mannose, glucose, and galactose with molar ratios of 1.49:1.67:1.00. The chemical structure of LPEPS-1 consisted of →4)-α-D-Glcp-(1→, →3)-α-D-Galp-(1→ and →2)-α-D-Manp-(1→. Scanning electron microscopy (SEM) revealed that LPEPS-1 had a relatively rough surface. In addition, LPPES-1 exhibited strong scavenging activity against DPPH and superoxide radicals and chelating ability on ferrous ion. This study demonstrated that soybean whey was a feasible fermentation substrate for the production of polysaccharide from L. plantarum 70810 and that the polysaccharide could be used as a promising ingredient for health-beneficial functional foods.

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Section: Uv and Ft-ir Spectra Analysismentioning

confidence: 99%

Structural Characterization and Antioxidant Activity of Exopolysaccharide from Soybean Whey Fermented by Lacticaseibacillus plantarum 70810

Tian

Mao

Dong

et al. 2021

Foods

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“…Polysaccharides are crucial bioactive components in C. militaris (Beltrame et al, 2019;Yang et al, 2019;Barcelos et al, 2020;Mohan et al, 2020;Wu et al, 2020). Polysaccharides are known to have antiviral, antioxidative, antiinflammatory, antitumor, neuroprotective, antihypertensive, and immunomodulatory biological effects (Sims et al, 2011;Lee et al, 2017;Rodrigues et al, 2020).…”

Section: Polysaccharidesmentioning

confidence: 99%

Trends in the Immunomodulatory Effects of Cordyceps militaris: Total Extracts, Polysaccharides and Cordycepin

et al. 2020

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Cordyceps militaris (C. militaris) is a fungus with a long history of widespread use in folk medicine, and its biological and medicinal functions are well studied. A crucial pharmacological effect of C. militaris is immunomodulation. In this review, we catalog the immunomodulatory effects of different extracts of C. militaris, namely total extracts, polysaccharides and cordycepin. Total extracts obtained using water or 50% ethyl alcohol and polysaccharides from C. militaris were discovered to tend to promote type 1 immunity, whereas total extracts obtained using 70–80% ethyl alcohol and cordycepin from C. militaris were more likely to promote type 2 immunity. This article is the first to classify the immunomodulatory effects of different extracts of C. militaris. In addition, we discovered a relationship between different segments or extracts and differing types of immunity. This review can provide the readers a comprehensive understanding on the immunomodulatory effects of the precious folk medicine and guidance on its use for both health people and those with an immunodeficiency.

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“…In contrast, Cordyceps militaris only takes one to three months to mature and therefore has greater potential for development and use. In addition, Cordyceps militaris can be cultivated in media and has functional components similar to Cordyceps sinensis, garnering it greater attention [22]. Cordyceps militaris is rich in a variety of bioactive compounds, such as cordycepin, polysaccharides, ergosterol, and mannitol [23].…”

Section: Edible Fungi and Their Potential Usesmentioning

confidence: 99%

The Effects of Fungal Feed Additives in Animals: A Review

Chuang

Hsieh

Lee

2020

Animals

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As probiotics, fungi enhance animal health and are suitable animal feed additives. In addition to brewing fungi, there are also edible and medicinal fungi. Common fungi utilized in feeding programs include Saccharomyces cerevisiae, Aspergillus oryzae, Pleurotus spp., Antrodia cinnamomea, and Cordyceps militaris. These fungi are rich in glucans, polysaccharides, polyphenols, triterpenes, ergosterol, adenosine, and laccases. These functional components play important roles in antioxidant, anti-inflammatory, anti-obesity, and immune system regulation. As such, fungal feed additives could be of potential use when breeding livestock. In previous studies, fungal feed additives enhanced body weight and egg production in poultry and improved the feed conversion rate. Several mycotoxins can be produced by hazardous fungi but fortunately, the cell walls constituents and enzymes of fungal probiotics can also act to decrease the toxicity of mycotoxins. Overall, fungal feed additives are of value, but their safety and usage must be studied further, including cost-benefit economic analyses.

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Chemical structure and inhibition on α-glucosidase of the polysaccharides from Cordyceps militaris with different developmental stages

Cited by 51 publications

References 52 publications

Structural Characterization and Antioxidant Activity of Exopolysaccharide from Soybean Whey Fermented by Lacticaseibacillus plantarum 70810

Structural Characterization and Antioxidant Activity of Exopolysaccharide from Soybean Whey Fermented by Lacticaseibacillus plantarum 70810

Trends in the Immunomodulatory Effects of Cordyceps militaris: Total Extracts, Polysaccharides and Cordycepin

The Effects of Fungal Feed Additives in Animals: A Review

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