Chemical shifts of the protons of the primary amine group and its structure

Kapkan, L. M.; Титов, Е. В.

doi:10.1016/0022-2860(73)85278-0

Cited by 4 publications

(4 citation statements)

References 13 publications

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“…The RM structure of 2 is disrupted in DMSO as substantiated by 1 H NMR data. In this solvent, the amide proton signals display splittings characteristic of acetamide in a diamagnetic environment with a resonance at 7.6 ppm (d, 2H) . Additionally, the spectrum in DMSO shows a slight broadening of all the CDA protons.…”

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confidence: 97%

Amide−Ligand Hydrogen Bonding in Reverse Micelles

et al. 2005

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One approach to modeling the second coordination shell of metalloproteins is to pair amide-containing counterions with metal complexes to form hydrogen bonds in the solid state. In a more general approach, we have designed a surfactant counterion that can sustain hydrogen bonding interactions with metal complexes in solution. The surfactant is cationic and incorporates an amide as part of its headgroup to form hydrogen. The surfactant forms hydrogen bonding reverse micelles that accommodate anionic metal complexes in their polar core. In reverse micelles containing an iron(III) hexacyanide complex, spectroscopic evidence suggests that the anion is confined to the polar core region in solution. Single-crystal X-ray diffraction data on the surfactant ferricyanide system reveals a layered structure with interdigitated alkyl chains and an extensive network of hydrogen bonds that link amide groups to the cyanide ligands and to neighboring headgroups.

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confidence: 97%

Amide−Ligand Hydrogen Bonding in Reverse Micelles

et al. 2005

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“…As demonstrated in Figure 7A, the H‐NMR spectrum of dsDNA represents separated peaks in the range of 1–1.8 ppm, which is attributed to the presence of aliphatic (sp 3 ) C–H protons of thymine bases in the DNA structure. The signals recorded at 6–6.21 ppm were attributed to the protons of –NH 2 groups in the adenine and cytosine bases 45 . Peaks at the region of 7.6–8.03 are ascribed to the protons of NH groups in the adenine and guanine bases.…”

Section: Resultsmentioning

confidence: 96%

“…The signals recorded at 6-6.21 ppm were attributed to the protons of -NH 2 groups in the adenine and cytosine bases. 45 Peaks at the region of 7.6-8.03 are ascribed to the protons of NH groups in the adenine and guanine bases. In addition, separate peaks were observed at the region of 1.62, 2.2-2.45, 3.18-3.32, and 4.07-4.27 ppm referring to the C-H groups of the deoxyribose sugar.…”

Section: F I G U R E 4 Characterization Of the Bio-dot (A) Exd Analys...mentioning

confidence: 99%

Synthesis and characterization of N‐rich fluorescent bio‐dots as a reporter in the design of dual‐labeled FRET probe for TaqMan PCR: A feasibility study

Imani

Mohajeri

Rastegar

et al. 2022

Biotech and App Biochem

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DNA‐based analytical techniques have provided an advantageous sensing assay in the realm of biotechnology. Bio‐inspired fluorescent nanodots are a novel type of biological staining agents with excellent optical properties widely used for cellular imaging and diagnostics. In the present research, we successfully synthesized bio‐dots with excellent optical properties and high‐quantum yield from DNA sodium salt through the hydrothermal method. We conjugated the bio‐dots with 3' Eclipse Dark Quencher (Eclipse)‐labeled single‐strand oligodeoxyribonucleotide according to carbodiimide chemistry, to design a fluorescence resonance energy transfer (FRET) probe. The results confirmed the prosperous synthesis and surface functionalization of the bio‐dot. Analysis of size, zeta potential, and FTIR spectroscopy verified successful bioconjugation of the bio‐dots with probes. UV‐visibility analysis and fluorescence intensity profile of the bio‐dot and bio‐dot@probes represented a concentration‐dependent quenching of fluorescent signal of bio‐dot by Eclipse after probe conjugation. The results demonstrated that TaqMan PCR was not feasible using the designed bio‐dot@probes. Our results indicated that bio‐dot can be used as an efficient fluorescent tag in the design of fluorescently labeled oligonucleotides with high biocompatibility and optical features.

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“…group as a function of the dielectric constant of the solvent (817), lithioisobutyrophenone and its complexes with lithium chloride and bromide (818), alicyclic methyl esters (819) , oligo(oxy-2,2-dimethylethylenecarbonyl) compounds (820) , alkyl substituted furans (821), benzofurans (822), 2-substituted furans, thiophenes, and tellurophenes (823), methyl-substituted 1,3-oxothianes (824), 2-amino-4phenylbenzothiazoles (825), barbiturates (826), coumarin and its methyl derivatives (827), and 5-alkyl-5-(l-methylbutyl)barbituric acids (828) have been described. The NMR determination of electronic densities in quinoxalines and quinolines (829), and symmetrical naphthyridines (830), additivity effects on the H-H coupling constants of disubstituted pyridines (831), 13C-F coupling constants of fluoropyridines (832), medium effects on the 19F NMR of fluoropyridines (833), 13C NMR line intensity measurements for quinoline and other compounds (834), cis and trans isomers of 2-chloroand 2-phenyl-5-methyl-1,3,2-oxathiaphospholane (835), sodium (p-methoxyphenyl)methylphosphinodithioate dihydrate (836), thioand di-thiooxamides (837), derivatives of dithiocarbazic acids (838), quaternary ammonium salts (839), TV-substituted methylamines (840), 2-, 3-, and 4-substituted TV-methylpyridinium salts (841), n-alkyl ammonium salts (842), simple quaternary salts of 1 -methylpyrazole (843), complexes of nitrophenols with dialkylamines (844), nitrotoluidines (845), acyclic aliphatic amines (846), 5-substituted 10,11dihydrobenz[b,f]azepines (847), polytertiary amine chelated alkali metal compounds (848), acrylic amines (849), primary amines (850), pyrrole (851), pyrrole derivatives (852) and tetrapyrroles (853), 8-hydroxyquinoline (854) and its derivatives (855), protonation of L-cysteine (856), protected amino acids (857), determination of glutethimide (858), diazoalkanes (859), substituted pyrazoles (860), 1,4-oxathiane derivatives (861), l-alkyl-2(lH)-pyridinone derivatives (862), purine derivatives…”

Section: Lecithinmentioning

confidence: 99%