Chemical profile and antibacterial activity of acetone extract of Homalomena cochinchinensis Engl. (Araceae)

Abstract

Homalomena cochinchinensis Engl. is a rare species which is found in Southern China, Cambodia, Laos and Vietnam and its chemical constituents and bioactivity have not been determined yet. In this study, we identified 32 and 38 compounds in acetone extracts of H. cochinchinensis aerial part and rhizome, respectively via gas chromatography mass spectrometry (GC/MS). The main constituents of acetone extract of the aerial part were 3-((4Z,7Z)-Heptadeca-4,7-dien-1-yl)phenol (18.73%); cis-9,cis-12-Octadecadienoic acid (12.04%); linolenic acid (11.08%); n-Hexadecanoic acid (10.13%); (Z)-3-(Heptadec-10-en-1-yl)phenol (7.09%); ?-Sitosterol (5.58%) and linalool (5.56%). On the other hand, acetone extract of rhizome contained linalool (28.42%); 1,2,3-Propanetriol, 1-acetate (10.13%); 3-((4Z,7Z)-Heptadeca-4,7-dien-1-yl)phenol (5.28%); 3-Buten-2-one, 3-methyl-4-(1,3,3-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl)- (5.28%) and 4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butyric acid (4.54%). Furthermore, this study has also proved the antibacterial activity of acetone extracts from the aerial part and the rhizome of this species for the first time using disk diffusion method. The results showed that the extract of the aerial part could inhibit the growth of 5 out of a total 6 bacterial strains, including Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enteritidis and Staphylococcus aureus; while the susceptible strains to the rhizome extract were 5 strains, such as B. cereus, E. coli, P. aeruginosa, Salmonella typhimurium and S. aureus. The findings suggest the further application of this species in pharmacology and medicine.

Chemical profiles and antibacterial activity of acetone extract of two Curcuma species from Vietnam

“…The electron impact ionization was set as 70 eV and the filament source temperature was set at 250 0 C. The acquisitions scan mass range of MS was 29-650 m/z with the scanning frequency of 2 scans/sec. The chemical components of the acetone extracts were identified based on the comparison between their mass spectra and the NIST 2017 library (15).…”

Volatile Components and Biological Activities of n-Hexane Extract From Rhizomes of Homalomena cochinchinensis

“…Previous studies have reported high linalool content in the acetone extract of both rhizomes and the aerial parts of H cochinchinenesis. 7 Linalool was also reported as the major constituent of many Homalomena essential oils such as H aromatica rhizome (62.5%), 11 H aromatica root (58.3%), 12 H occulta rhizome (36.9%), 13 and H sagittifolia rhizome (61.9%). 14 Collectively, linalool is considered one of the chemical markers of the Homalomena genus.…”

“…5 Recent reports have also described the antibacterial activity of rhizome essential oil and constituents in the acetone extract of H cochinchinensis. 6,7 Investigating the composition and biological activities of H cochinchinensis rhizomes is important for clarifying the role of this plant in folk medicine. As part of an ongoing investigation of bioactive metabolites from plants of the Homalomena genus collected in Vietnam, [8][9][10] we report herein the composition of volatile components from H cochinchinensis rhizomes.…”

CHEMICAL COMPOSITION, ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES OF ACETONE EXTRACT FROM LEAF AND FRUIT PEEL OF Citrus hystrix

“…Another example was of Terpinen 4-ol. This component was found to have several biological and pharmacological properties, including antiviral, anti-biofilm, anti-cancer, anti-inflammatory activities [12]. In a study by Shapira et al (2016), terpinen-4-ol was proven to be able to inhibit the growth of range of cancer cells, such as colorectal, gastric, pancreatic and prostate cancer cell lines in dose dependent manner [13].…”