Chemical Constituents of Artabotrys petelotii

Oanh, Nguyen Thi Tu; Le, Thanh Nguyen; Giap, Tran Huu; Hương, Đoàn Thị Mai; Cường, Phạm Văn; Hùng, Nguyễn Văn; Minh, Châu Văn; Hang, Nguyen Thi Minh

doi:10.1007/s10600-019-02696-6

Cited by 3 publications

(13 citation statements)

References 10 publications

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“…Table 2 is designed to contain chemical groups, the alphabetic names of these isolates, and their botanical resources, whereas Figures 234567 provide fully structural images with their detailed configuration. They include alkaloids 1 – 78 , [2,4,8,10–12,18,19,24,27,28,31–45] terpenoids 79 – 142 , [11,14,21,24,25,27,35,41,46–53] sterols 143 – 154 , [11,23,24,50,51,54–57] flavonoids 155 – 176 , [4,11,20,50,57–59] polyoxygenated compound s 177 – 195 , [24,49,59–61] fatty acids 196 – 212 , [20,55,62–64] furans 213 – 217 , [11,49,65] acetogenins 218 – 221 , [24,65,66] and other types 221 – 234 [4,11,24,54,57,58,67] …”

Section: Phytochemistrymentioning

confidence: 99%

“…Of Artabotrys species, triterpenoids highly concentrated on the parts of two species A. odoratissimus and A. pilosus . A list of eighteen compounds 125 – 142 was summarized in Table 2 and Figure 4 [11,21,24,25,41,49–51] . Phytochemical research conducted by Tong‐Wei et al revealed that the alcoholic extract of A. pilosus twig and leaf consisted of a great number of triterpenoids, in which nine ones were isolated, including β‐amyrin ( 125 ), betulinic acid ( 132 ), dammaradienyl acetate ( 133 ), erythrodiol ( 134 ), friedelin ( 135 ), friedelinol ( 136 ), lupeol ( 137 ), lupenyl acetate ( 138 ), and uvaol ( 142 ) [51] .…”

Section: Phytochemistrymentioning

confidence: 99%

“…Sterols also appeared as the next chemical class in the isolation processes of Artabotrys extracts. Herein, twelve compounds 143 – 154 were compiled in Table 2 and Figure 4 [11,23,24,50,51,54–57] . By NMR analysis, 2 β ‐hydroxy‐stigmasta‐4‐en‐3,6‐dione‐methoxy ester ( 143 ) was elucidated as new sterol, and was arisen from A. odoratissimus leaf, while the known compound ergosterol ( 144 ) appeared in its seed [23,57] .…”

Section: Phytochemistrymentioning

confidence: 99%

“…However, β‐sitosteryl‐3‐ O ‐β‐D‐glucoside ( 146 ) was a glycoside derivative of 145 , which was only found in A. hexapetalus seed, and A. uncinatus stem [11,54] . Similarly, glycoside derivative of 148 , stigmasteryl‐3‐ O ‐β‐D‐glucoside ( 149 ), was only present in A. petelotii leaf, and A. uncinatus stem [11,50] . A. pilosus twig and leaf contributed three sterols α‐spinasterone ( 147 ), stigmast‐5‐ene‐3β‐ol‐7‐one ( 150 ), stigmast‐7‐ene‐3β‐ol ( 151 ), and stigmastane‐3,6‐dione ( 152 ) [51] .…”

Section: Phytochemistrymentioning

confidence: 99%

“…They included flavones 155 – 173 , flavan 174 , flavanone 175 , and pterocarpan 176 ( Table 2 and Figure 5). [4,11,20,50,57,58,60] …”

Section: Phytochemistrymentioning

confidence: 99%

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Botanical Description, Traditional Uses, Phytochemistry, and Pharmacology of the Genus Artabotrys: A Review

Hợp

Son

2022

Chemistry & Biodiversity

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Artabotrys is a genus of small trees in the family Annonaceae. This genus contained over 100 perennial medicinal plants available in the old world tropics. Artabotrys plants have a lengthy history of use in medicine for malaria, diarrhea, backache, and scrofula treatments, as well as some of which were used as tea-like beverages. About 90 reports were reviewed from inception to now, in which the decoctions of about 9 species were used in traditional folk medicines. With 234 isolated compounds, Artabotrys metabolites can be classified as alkaloids, terpenoids, sterols, flavonoids, polyoxygenated cyclohexenes, fatty acids, acetogenins, etc. Significantly, alkaloidal aporphines were separated and identified as the main isolates. Artabotrys plants are also rich in the essential oils. Especially, A. hexapetalus exerted a great role in perfumery industry. Artabotrys constituents possessed various pharmacological values, such as antioxidative, antidiabetic, hepatoprotective, and mosquito repellency, but cytotoxic and antimicrobial activities are the most striking features. In conclusion, Artabotrys plant extracts and their metabolites are of great socio-economic importance, thereby more and more phytochemical and pharmacological investigations are expected.

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Section: Phytochemistrymentioning

confidence: 99%

Section: Phytochemistrymentioning

confidence: 99%

Section: Phytochemistrymentioning

confidence: 99%

Section: Phytochemistrymentioning

confidence: 99%

“…They included flavones 155 – 173 , flavan 174 , flavanone 175 , and pterocarpan 176 ( Table 2 and Figure 5). [4,11,20,50,57,58,60] …”

Section: Phytochemistrymentioning

confidence: 99%

See 3 more Smart Citations

Botanical Description, Traditional Uses, Phytochemistry, and Pharmacology of the Genus Artabotrys: A Review

Hợp

Son

2022

Chemistry & Biodiversity

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Phytochemical Profiling and Compound Isolation of Cissus rhombifolia Vahl. Leaves Aqueous Methanolic Extract with the Evaluation of Its Anti‐Inflammatory Effect Using Lipopolysaccharide‐Induced Inflammation in RAW 264.7 Cells

Raslan¹,

Mounier²

2023

Chemistry & Biodiversity

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The inflammatory disorders represent a serious health issue. Certain Cissus species possess anti-inflammatory effect. Cissus rhombifolia Vahl. leaves' anti-inflammatory activities and phytoconstituents are poorly characterized. In this study, 38 constituents were tentatively characterized in Cissus rhombifolia Vahl. leaves' aqueous methanolic extract (CRLE) using high-performance liquid chromatography combined with mass spectrometry (HPLC/MS) and Proton Nuclear Magnetic Resonance ( 1 H-NMR). Myricetin, β-amyrin, and alliospiroside A, were isolated from CRLE using column chromatography. The anti-inflammatory effect of CRLE and its isolated compounds were studied in lipopolysaccharide (LPS)-induced RAW 264.7 cells. 3-(4,5dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT as-say) was used to assess how CRLE and its isolated compounds affected cell viability. Further, its effects on the production of intracellular NO, and inflammatory cytokines cyclooxygenase-2 (COX-2), tumor necrosis factor alpha (TNF-α), and interleukin 6 (IL-6) were assessed by the Griess test, and cytokine enzymelinked immunosorbent assays, respectively. CRLE and its isolated compounds, myricetin, β-amyrin, and alliospiroside A decreased the NO production. Western blotting was performed to assess the protein expression levels of the inflammatory cytokines inducible nitric oxide synthase (iNOS). Alliospiroside A downregulated IL-6, TNF-α, and COX-2 and inhibited the expression of iNOS. CRLE and its compounds represent effective alternative candidate to treat inflammatory diseases.

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Anti-inflammatory effect and chemical constituents of Microcos paniculata total flavone glycosides fraction

Yuan

Zhang

Zhao

et al. 2019

IOP Conf. Ser.: Earth Environ. Sci.

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Microcos paniculata is an edible and medicinal plant in Lingnan, China. The present study investigated the anti-inflammatory effect and chemical constituents of its’ total flavone glycosides (MpTFG) fraction. MpTFG (10, 15, 20 μg/mL) was applied to 1 μg/mL LPS-induced RAW 264.7 macrophages in vitro; and MpTFG (10, 20, 40 mg/kg body weight) was employed to xylene-induced ear edema test. As a result, 20 μg/mL MpTFG decreased the levels of pro-inflammatory cytokines IL-6, IL-1β and TNF-α in LPS-stimulated RAW 264.7 cells supernatant significantly, and 40 mg/kg MpTFG could effectively ameliorate xylene-induced mice ear swelling. The results showed that MpTFG had potential anti-inflammatory effect. Meanwhile, ten compounds were purified by making use of macro-porous resin, sephadex LH-20 gel column chromatography and semi-preparation HPLC successively. They were characterized to be vicenin-2 (i), isoschaftoside (ii), schaftoside (iii), vitexin (iv), vicenin-1 (v), isovitexin (vi), isoviolanthin (vii), nicotiflorin (viii), astragalin (ix), narcissoside (x) by 1H-NMR, 13C-NMR and HRMS spectral analysis.

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Chemical Constituents of Artabotrys petelotii

Cited by 3 publications

References 10 publications

Botanical Description, Traditional Uses, Phytochemistry, and Pharmacology of the Genus Artabotrys: A Review

Botanical Description, Traditional Uses, Phytochemistry, and Pharmacology of the Genus Artabotrys: A Review

Phytochemical Profiling and Compound Isolation of Cissus rhombifolia Vahl. Leaves Aqueous Methanolic Extract with the Evaluation of Its Anti‐Inflammatory Effect Using Lipopolysaccharide‐Induced Inflammation in RAW 264.7 Cells

Anti-inflammatory effect and chemical constituents of Microcos paniculata total flavone glycosides fraction

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