Chemical Composition of Sweat

Robinson, Sarah; Robinson, Aline H.

doi:10.1152/physrev.1954.34.2.202

Cited by 341 publications

(206 citation statements)

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“…Thaysen & Schwartz (1955) found that thermally fatigued glands, like methacholine-treated glands, failed to respond to methacholine. In heat-induced fatigue the decline in sweat rate is associated with a sustained or rising skin temperature and a rise in salt output of the sweat (Robinson & Robinson, 1954). Dole, Stall & Schwartz (1951), however, failed to show any increase in the sodium concentration of sweat collected during repeated stimulation by methacholine when the rate of flow decreased.…”

mentioning

confidence: 97%

Excitation and depression of eccrine sweat glands by acetylcholine, acetyl‐β‐methylcholine and adrenaline

Collins¹,

Sargent²,

Weiner³

1959

The Journal of Physiology

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mentioning

confidence: 97%

Excitation and depression of eccrine sweat glands by acetylcholine, acetyl‐β‐methylcholine and adrenaline

Collins¹,

Sargent²,

Weiner³

1959

The Journal of Physiology

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“…Thaysen & Schwartz (1955) suggest that the decrease in sweat gland activity by repeated injections of drugs is due to 'fatigue' of the glands. We have found, however, that the depression by drugs does not necessarily entail prolonged or intense secretory activity and that the NaCl concentration of the sweat does not increase as is the case in thermal sweat gland 'fatigue' (Robinson & Robinson, 1954). Previous experiments have shown that the depression is not simply due to physical damage to the glands by repeated injections or to impairment of the local blood supply.…”

Section: Pmentioning

confidence: 57%

Proceedings of the Physiological Society

1959

The Journal of Physiology

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Many students are helped by seeing Lillie's model. An alternative electrolyte has been found which is less noxious than strong nitric acid with its fumes, gives a cleaner reaction, and permits greater control of the conditions. The original model consisted of an iron wire rendered 'passive' in strong nitric acid (Lillie, 1918(Lillie, , 1919(Lillie, , 1920(Lillie, , 1922. The wire is 'stimulated' with a piece of zinc, or by other chemical, mechanical or electrical methods. Refractory period, threshold phenomena, summation, electrotonus, etc., can all be imitated.The action of the acid is twofold: (1) it causes oxidation, depositing a film on the wire, (2) it acts as an acid, attacking the wire at the active portion. A mixture of hydrogen peroxide solution and nitric acid in which the proportion of acid is low (c. 3 %) produces the same result, is cleaner, and allows the two effects to be controlled by varying the proportions in the mixture.To obtain a slow impulse which is easy to see, thick wire should be used (gauge 10). It should be relatively pure, commercial galvanized iron wire being suitable if the galvanizing is first removed with dilute hydrochloric acid; the wire is then washed in water and wiped on a clean cloth. Place the iron wire in a flat dish, and cover with a mixture of hydrogen peroxide (20 vol.) and concentrated nitric acid in the proportion 30:1. Add more acid drop by drop, testing the wire with a piece of zinc, until satisfactory propagation is achieved. If too much acid is added, causing the wire to effervesce continuously, more peroxide can be added. a

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“…This fact is important because the output of certain solutes is reported to be directly related to the amount taken into or formed by metabolism in the body (14, 16, 59, 71,77,96,98,128).…”

Section: Discussionmentioning

confidence: 99%