Chemical composition and larvicidal activity of Piper capense essential oil against the malaria vector, Anopheles gambiae

Matasyoh, Josphat C.; Wathuta, E. M.; Kariuki, S. T.; Chepkorir, Regina

doi:10.1016/j.aspen.2010.11.005

Cited by 17 publications

(14 citation statements)

References 8 publications

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“…Essential oil extracts or isolated compounds of some Piper species against larvae of A. aegypti or A. gambiae had much lower LC than crude aerial extracts. Morais et al (2007) related an LC50 54 and 36 ppm of the essential oils of P. hostmanianum and P. pernocronatum on A. aegypti and Matasyoh et al (2011) found that P. capense essential oil had an LC50 34,9 and LC90 85 ppm on A. gambiae. Despite of that, essential oils of P. jacquemontianum and P. variabili had no activity on A. albimanus and A. aegypti even at 1000 ppm (Cruz et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of larvicidal activity of the methanolic extracts of Piper alatabaccum branches and P. tuberculatum leaves and compounds isolated against Anopheles darlingi

Trindade¹,

Stábeli²,

Facundo³

et al. 2012

Rev. bras. farmacogn.

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Abstract:Piper is a notable genus among Piperaceae due to their secondary metabolites such as lignans, amides, esters and long chain fatty acids used as antiherbivore defenses with comparable effects of pyrethroids, that holds a promise in insect control, including malaria vectors such as Anopheles darlingi, the main vector in the North of Brazil. Methanolic extracts of Piper tuberculatum Jacq., Piperaceae, and P. alatabaccum Trel. & Yunck., Piperaceae, and some isolated compounds, i.e, 3,4,5-trimetoxy-dihydrocinamic acid, dihydropiplartine; piplartine, piplartine-dihydropiplartine and 5,5',7-trimetoxy-3',4'-metilenodioxiflavone were tested as larvicides against A. darlingi. The Lethal Concentrations (LC50 and LC90) of methanolic extracts were 194 and 333 ppm for P. tuberculatum and 235 and 401 ppm for P. alatabacum, respectively. Isolated compounds had lower LC values, e.g. the LC50 and LC90 of the piplartine-dihidropiplartine isolated from both plant species was 40 and 79 ppm, respectively.

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Section: Discussionmentioning

confidence: 99%

“…Cruz et al, 2011) or anophelines only (e.g. Matasyoh et al, 2011). The larval mortality caused by the crude extracts tested against the main malaria vector in Brazil, i.e.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of larvicidal activity of the methanolic extracts of Piper alatabaccum branches and P. tuberculatum leaves and compounds isolated against Anopheles darlingi

Trindade¹,

Stábeli²,

Facundo³

et al. 2012

Rev. bras. farmacogn.

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“…The essential oils obtained from leaves and fruits collected in the western province of Cameroon were reported to show negligible antifungal activity [10]. Other papers described the toxicity of the essential oil against the insect infecting maize grains, Sitophilus zeamais [11], and the larvicidal activity against the malaria vector Anopheles gambiae [12].…”

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confidence: 99%

“…The aerial parts of P. capense growing in S. Tomé and Principe [2] were also characterized by monoterpenes such as β-pinene (32.5%) and α-pinene (8.6%), and sesquiterpenes such as (E)-caryophyllene (12.6%), along with a low content of sabinene (0.7%), and benzenepropanoic acid ethyl ester (7.8%), which was not detected in our study. Finally, the essential oil obtained from the whole plant collected in Kenya [12] showed a different composition consisting mainly of sesquiterpene hydrocarbons (43.9%) such as δ-cadinene (16.8%), β-bisabolene (5.6%) and bicyclogermacrene (3.3%), while monoterpene hydrocarbons, including β-pinene (7.2%) and α-phellandrene (4.8%), were less abundant (30.6%).…”

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confidence: 99%

Antioxidant, Antiproliferative and Antimicrobial Activities of the Volatile Oil from the Wild Pepper Piper capense Used in Cameroon as a Culinary Spice

Woguem

Maggi

Fogang

et al. 2013

Natural Product Communications

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Wild pepper (Piper capense L.f., Piperaceae) is a spice traditionally used in western Cameroon to make soups called 'Nkui' and 'Nah poh'. In the present work, the essential oil hydrodistilled from fruits was analyzed by GC-FID and GC-MS, and for in vitro biological activities, namely cytotoxic, antioxidant and antimicrobial, by MTT, DPPH, ABTS and agar disc diffusion methods. The oil composition was dominated by monoterpene hydrocarbons (56.5%) responsible for the pepper odor, such as β-pinene (33.2%), sabinene (10.0%) and α-pinene (8.9%). The oil induced a concentration-dependent inhibitory effect on human tumor cells MDA-MB 231 (breast adenocarcinoma), A375 (malignant melanoma) and HCT116 (colon carcinoma), showing IC 50 values of 26.3, 76.0 and 22.7 μg/ml, respectively. The oil showed total antioxidant activity with a Trolox equivalent antioxidant concentration (TEAC) value of 140 µmol/g. The essential oil of P. capense proved to be an effective scavenger of the ABTS + radical, with an activity only about 30 times lower than that of Trolox. Moderate activity was observed against the Gram-positive species Staphylococcos aureus and Enterococcus faecalis, and the yeast Candida albicans. The notable inhibition of some human tumor cells is worthy of further investigation to discover the possible mechanisms of action responsible for the observed cytotoxic effect of this essential oil.

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“…Piperaceae species have a wide distribution, economic importance, ethnobotanic utility, chemical diversity and proven biological activity [1]; insecticidal activity has been widely studied, especially in the Piper genus [2][3][4][5][6][7][8][9][10][11]. P. septuplinervium (vine) and P. subtomentosum (tree) are commonly known as cords and distributed in Colombia.…”

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confidence: 99%

Chemical Composition and Insecticidal Properties of Essential Oils of Piper septuplinervium and P. subtomentosum (Piperaceae)

Murilloa

2014

Natural Product Communications

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Essential oils of Piper subtomentosum (leaves and inflorescences) and Piper septuplinervium (aerial parts) were analyzed by GC-MS; sixty-three compounds were determined, representing 92.0%, 86.9 %, and 91.8 % of the total relative oil composition of the leaves, inflorescences, and aerial parts, respectively. The most abundant component in the aerial parts and inflorescence oils was α-pinene (27.3%, 21.0%, respectively), and δ-cadinene was the main component of the leaf oil. Insecticidal activity of the essential oils were determined on the Spodoptera frugiperda second instar larvae; the essential oil from the aerial parts of P. septuplinervium was the most active against insect pests (LC 50 = 9.4 μL/L of air). Statistical analysis by direct Pearson correlation showed that the insecticidal activity of the essential oils was primarily due to camphene and α-and β-pinene. The effect of the oils on the insect life cycle was also evaluated, and in some cases, a delay in growth and inhibition of the oviposition in the females were observed.

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Chemical composition and larvicidal activity of Piper capense essential oil against the malaria vector, Anopheles gambiae

Cited by 17 publications

References 8 publications

Evaluation of larvicidal activity of the methanolic extracts of Piper alatabaccum branches and P. tuberculatum leaves and compounds isolated against Anopheles darlingi

Evaluation of larvicidal activity of the methanolic extracts of Piper alatabaccum branches and P. tuberculatum leaves and compounds isolated against Anopheles darlingi

Antioxidant, Antiproliferative and Antimicrobial Activities of the Volatile Oil from the Wild Pepper Piper capense Used in Cameroon as a Culinary Spice

Chemical Composition and Insecticidal Properties of Essential Oils of Piper septuplinervium and P. subtomentosum (Piperaceae)

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