Chemical Composition and Biological Activity of the Essential Oil of the Fruit of<i>Taxodium distichum</i>L. Rich Growing in Egypt

Tantawy, Mona E. El; Sakhawy, Fatma S. El; Sohly, Mahmoud A. El; Ross, Samir A.

doi:10.1080/10412905.1999.9701161

Cited by 24 publications

(21 citation statements)

References 13 publications

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“…Finally, since -pinene was found in all of the essential oils studied, it is a probable candidate for hypotension and bradycardia. As a matter of fact -pinene was reported to induce spasmolytic effect (El Tantawy et al, 1999). However, considering that OEOD from the leaves was able to induce the most important hypotensive and bradycardic effects, and since the lowest amount of the compound was found in the OEOD from the leaves, this might not be the only compound responsible for the cardiovascular effects observed.…”

Section: Resultsmentioning

confidence: 98%

GC-MS analysis and cardiovascular activity of the essential oil of Ocotea duckei

Barbosa-Filho¹,

Cunha²,

Dias³

et al. 2008

Rev. bras. farmacogn.

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RESUMO: "Análise CG-EM e atividade cardiovascular dos óleos essenciais de Ocotea duckei". O óleo essencial obtido da destilação por vapor de água das folhas, caule, raíz e frutos de Ocotea duckei teve sua composição química analisada através de CG-EM. A atividade farmacológica desses óleos também foi avaliada, mostrando signifi cantes efeitos cardiovasculares. Quarenta e nove substâncias foram identifi cadas, constituída por uma mistura complexa de monoterpenos (45%) e sesquiterpenos (55%). Os frutos forneceram (1,9%) mais óleo essencial do que os caules (1,0%), raízes (0,8%) e folhas (0,7%). O principal componente encontrado nas folhas foi o trans-cariofi leno (60,54%), nas cascas do caule, -eudesmol (27,51%) e nos frutos, dl-limoneno (30,12%). O componente predominante do óleo essencial das raízes foi elemol (24,31%). Em ratos normotensos, não anestesiados, o óleo essencial de diferentes partes de Ocotea duckei (folhas, frutos, caule e raiz) induziu signifi cante (p 0,05) hipotensão seguido de bradicardia. Unitermos:Ocotea duckei, Lauraceae, óleo essencial, análise CG-EM, atividade cardiovascular. ABSTRACT:The essential oils obtained by steam distillation from the roots, stems, leaves and fruits of Ocotea duckei had their composition analyzed by GC-MS. The pharmacological activity of these oils was also evaluated showing signifi cant cardiovascular effects. Forty-nine substances were identifi ed, consisting of a complex mixture of monoterpenes (45%) and sesquiterpenes (55%). The fruits yielded (1.9%) more essential oil than the stems (1.0%), roots (0.8%) and leaves (0.7%). The main component in the oil of the leaves was trans-caryophyllene (60.54%), in the stem bark -eudesmol (27.51%) and in the fruits, dl-limonene (30.12%). The predominant essential oil component in the roots was elemol (24.31%). In non-anaesthetized normotensive rats, the essential oils from different parts of Ocotea duckei (leaves, fruits, stem and roots) induced signifi cant (p < 0.05) hypotension followed by bradycardia.

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Section: Resultsmentioning

confidence: 98%

GC-MS analysis and cardiovascular activity of the essential oil of Ocotea duckei

Barbosa-Filho¹,

Cunha²,

Dias³

et al. 2008

Rev. bras. farmacogn.

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“…Several essential oils are reported to exhibit spasmolytic activity (Prakash et al, 2006;Astudillo et al, 2004;El Tantawy et al, 1999;Gamez et al, 1990;Zafra-Polo et al, 1989). Monoterpenes are the major components of these oils.…”

Section: Resultsmentioning

confidence: 99%

Structure and Spasmolytic Activity Relationships of Monoterpene Analogues Found in Many Aromatic Plants

Sousa

Júnior

Andrade

et al. 2008

Zeitschrift Für Naturforschung C

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Rotundifolone, a monoterpene isolated from the essential oil of the leaves of Mentha ¥ villosa, is a constituent of several essential oils and known to have spasmolytic activity. The present study aimed to investigate the correlation between structure and spasmolytic activity of rotundifolone and its analogues in ileum isolated from guinea-pig. Five of the seven tested analogues were found to have a spasmolytic effect more potent than rotundifolone itself, except for pulegone and (+)-limonene. The comparison between rotundifolone and limonene oxide showed that the absence of the keto group did not decrease the relaxant effect. Comparison of the spasmolytic activity between rotundifolone and (+)-pulegone showed that the absence of the epoxy group did not decrease the relaxation of the ileum. Carvone epoxide was found to be significantly more potent than rotundifolone. The monoterpene (Ð)-carvone produced ileum relaxation and was more potent than its enantiomer (+)-carvone. (+)-Limonene and pulegone oxide showed a similar effect. The study showed that the functional groups and their position at the ring of rotundifolone contributed to the relaxation activity of the ileum. The absence of the oxygenated molecular structure is not a critical requirement for the molecule to be bioactive.

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“…In Egypt, the cone oil was composed predominately of monoterpenoids with α-pinene as the major compound. 46 compounds were detected from the essential oils obtained by steam distillation (0.8% v/w) from the cone of the baldcypress and the major constituents included α-pinene (87.3%), thujopsene (3.7%), myrcene (2.0%), β-pinene (1.7%), limonene (1.3%), and camphene (1.0%) [27]. The compositions of the essential oil of baldcypress from Nigeria or Italy are similar to that in Egypt.…”

Section: Chemical Composition Of Essential Oilsmentioning

confidence: 99%

“…To date, only two C-32 cycloartane-type triterpenoids, cycloneolitsol (26) and cyclobalanone (27), were isolated from the leaves of extant T. distichum var. imbricarium [37].…”

Section: Triterpenoidsmentioning

confidence: 99%

“…The essential oil from the cones of baldcypress trees grown exhibited potent antimicrobial activities against bacteria Bacillus subtilis (ATCC 6633), Stapbylococcus aureus (ATCC 6536), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922), Proteus mirabtlis (ATCC 4630), Klebsiella pneumonia (ATCC 10031), and Citrbacter diwersus (CI 98) and the fungus Candida albicanswas (ATCC 32354) [27]. However, it is interesting that the oil of the leaves and cones collected from Nigeria exhibited only weak antibacterial activities against B. cereus (ATCC 14579), S. aureus (ATCC 29213), P. aeruginosa (ATCC 27853), and E. coli (ATCC 25922) (MIC >150 µg/mL) but potent activity against the fungus Aspergillus niger (ATCC 16401) (19.5 µg/mL) [29].…”

Section: Antimicrobial Activitiesmentioning

confidence: 99%

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Ethnobotany, Phytochemistry, and Biological Activities of Taxodium Rich.

Li¹

2013

TOPHARMCJ

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Taxodium Rich. is a genus of the family Cupressaceae. The trees are especially prized for their rot and termite resistant wood. Taxodium leaves and cones, which are particularly rich in essential oils were used as folk medicine to treat skin, gastro-intestinal, respiratory, inflammation, and infections. Preliminary bioactivity assays reported antimicrobial, antitumor, antitermitic, antispasmodic and bronchodilator activities of the extracts or isolates from Taxodium but further pharmacological investigations of bioactive compounds are not available. To data, at least 130 compounds have been identified from extant or fossil Taxodium. Fifty-seven compounds have been isolated primarily from the cones, leaves, and branches of extant Taxodium, with diterpenoids and flavonoids as the major components. At least three major abietane diterpenoids (sugiol (1), ferruginol (2), and 6,7-dehydroferruginol (3)) are also identified in the fossil Taxodium by GC/MS. The diterpenoids may be important marker compounds for understanding the evolution of the genus Taxodium. However, the taxonomy and evolutionary pattern of Taxodium remains elusive until a full understanding of the chemical constituents of all Taxodium taxa is determined.

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Chemical Composition and Biological Activity of the Essential Oil of the Fruit ofTaxodium distichumL. Rich Growing in Egypt

Cited by 24 publications

References 13 publications

GC-MS analysis and cardiovascular activity of the essential oil of Ocotea duckei

GC-MS analysis and cardiovascular activity of the essential oil of Ocotea duckei

Structure and Spasmolytic Activity Relationships of Monoterpene Analogues Found in Many Aromatic Plants

Ethnobotany, Phytochemistry, and Biological Activities of Taxodium Rich.

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