Chemical Composition and Antimicrobial Activity of Cumin Oil (Cuminum Cyminum, Apiaceae)

Abstract

Cumin oil samples (Cuminum cyminum L.) from four different geographical origins were analyzed using GC-MS and GC-FID for their qualitative and quantitative composition. The major compounds in all cumin oils were the monoterpenes β-pinene, p-cymene and γ-terpinene and the terpenoid aldehydes cuminic aldehyde and the isomeric menthadien carboxaldehydes. All essential oils, and cuminic aldehyde, were tested, using agar diffusion and serial dilution methods, against different Gram-positive and Gram-negative bacteria isolated from different sources of food (pork fillet, minced meat and sausages) and clinical isolates, as well as three different Candida albicans isolates. All cumin oils and cuminic aldehyde exhibited a considerable inhibitory effect against all the organisms tested, except Pseudomonas spp.

Chemical composition of essential oils from the apiaceae family, cytotoxicity, and their antifungal activity in vitro against candida species from oral cavity

“…In the chromatographic analysis of the C. cyminum essential oil, the majority constituents were Cuminaldehyde, γ-terpinene, β-pinene, o-cymene, 2-caren-10-al, 1-phenyl-1-butanol and D-limonene agreeing with the results found by others authors, only with few variations (Shetty et al, 1994;Wanner et al, 2010;Kamble, 2015).…”

“…Shetty et al (1994), using the agar diffusion method, founding positive results, however with a minor inhibitory concentration of 0,10 mg.mL 1 . Pai et al (2010) and Wanner et al (2010) used the disk diffusion method, confirming the cumin as an anti-Candida potential agent. Kamble (2015), had good inhibition results against Candida albicans and not albicans using the disk diffusion and the broth micro and macrodilution techniques (Minimum Inhibitory Concetration).…”

“…Several studies have shown the excellent therapeutic properties of essential oils, meanwhile, in the assays of antifungal in vitro activity of the oils, it is possible to verified a variety of methodologies proposed, such are the agar diffusion, the disk diffusion and the broth dilution (Kosalec et al, 2005;Gulfraz et al, 2008;Pai et al, 2010;Wanner et al, 2010;Cavalcanti et al, 2011;Cleff et al, 2013;Kamble, 2015), making hard to compared between the present study and these studies. There by, the recognition of the pharmacologic activity of the presented plants in this study represents important information to evaluate the obtained viability of the product in clinical use.…”

Chemical and Microbiological Characterization of Egyptian Cultivars for Some Spices and Herbs Commonly Exported Abroad

“…The most significant compounds in LOC and M were cumin aldehyde and g-terpinene, respectively, while S and HOC were tetradecene and α-terpinyl acetate, respectively. However, different groups for volatile components than those found in EOs of the Egyptian cultivar were reported in literature [72].…”

Role of Dietary Supplements in Cardiovascular Diseases

“…Cumin (Cuminum cyminum L., Apiaceae) is characterized by its volatile oil constituents: the monoterpene hydrocarbons β-pinene, p-cymene and γ-terpinene and the terpenoid aldehydes mainly cuminic aldehyde. 228 Cumin was found to significantly reduce the plasma levels of cholesterol, triglycerides and phospholipids. It also decreases the activity of aspartate transaminase, alkaline phosphatase and gamma glutamyl transferase enzymes (non-specific indicators of tissue damage) and thus to be efficient in liver diseases (alcoholic liver disease, chronic hepatitis, cirrhosis, obstructive jaundice, hepatic cancer), myocardial infarction, pancreatitis and muscle-wasting diseases).…”