Chemical Characterization and Optimization of the Extraction Process of Bioactive Compounds from Propolis Produced by Selected Bees<i>Apis mellifera</i>

Oldoni, Tatiane Luiza Cadorin; Oliveira, Sheila Catarina de; Andolfatto, Suelen; Karling, Mariéli; Calegari, Matheus Augusto; Sado, Ricardo Yuji; Maia, Fabiana M. C.; Alencar, Severino Matias de; Lima, Vanderlei Aparecido de

doi:10.5935/0103-5053.20150186

Cited by 31 publications

(41 citation statements)

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“…Oldoni et al observed the influence of standardization of extraction. The results of their study confirmed that the optimization of the extraction conditions is important to obtain extracts that are rich in phenolic compounds and antioxidant activity of propolis [23].…”

Section: [29]supporting

confidence: 57%

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A Systematic Review of the Antioxidant Activity of Apiculture Products in Brazil

Araújo¹,

Neto²,

Mariano³

2017

Superfood and Functional Food - An Overview of Their Processing and Utilization

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The use of substances with antioxidant ability can be very important in the therapeutic prevention of diseases related to increased oxidative stress, such as cancer, heart disease and aging. Brazil has a great diversity of vegetation from which bees can collect resins. This study is a systematic bibliographical review on different electronic scientific databases through descriptors of antioxidant activity of bee products from Brazil. The identification of the articles and their inclusion occurred between the months January to MayW 2016. The bibliographic research was conducted in the following electronic databases: (1) Scientific electronic library online-SciELO; (2) Public library of science-PLOS Medicine; and (3) ScienceDirect. The articles selected were the ones that contained antioxidant activity evaluation of bee products from Brazil during 2011 and 2016. It was possible to observe a large number of articles published in this topic, but a compilation of data from all of these studies was necessary. Given there is a great diversity of vegetation in Brazil, a standardization process of the bee products in Brazil was conducted and by means of this process it was possible to draw a profile of the main antioxidants found in apiculture products in Brazil.

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Section: [29]supporting

confidence: 57%

“…11 [23] This work aims at optimization the extraction process of bioactive compounds, evaluate antioxidant activity and also conduct the chemical characterization of propolis, using the high performance liquid chromatography technique.…”

Section: The Botanical Origin Of Propolis Samples Is Difficultmentioning

confidence: 99%

A Systematic Review of the Antioxidant Activity of Apiculture Products in Brazil

Araújo¹,

Neto²,

Mariano³

2017

Superfood and Functional Food - An Overview of Their Processing and Utilization

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“…Thus, the optimum extraction condition for phenolic compounds with high antioxidant activity was obtained with the ethanol (800 g/L) at 60 °C during 60 minute of extraction. Oldoni et al (2015), evaluated the extraction conditions of phenolic compounds from propolis with different ethanol concentrations, temperature and time. The authors reported that the best condition was found with ethanol (800 g/L) at 70 °C during 45 min of extraction.…”

Section: Resultsmentioning

confidence: 99%

“…All standards were dissolved in phase "B" at the following concentrations: 2 µg/mL; 4 µg/mL; 8 µg/mL; 16 µg/mL; 30 µg/mL. These concentrations were used afterwards for obtaining the limit of quantification (LQ) of 0.35 µg/mL and the detection limit (LD) of the equipment of 0.12 µg/mL employing standards of gallic acid, vanillic acid, caffeic acid, coumaric acid, and ferulic acid according to Oldoni et al (2015). The content phenolic compounds were expressed for each compound in µg/g of sample.…”

Section: Hplc-dad-uv-vis Profilementioning

confidence: 99%

Optimization of phenolic compounds extraction with antioxidant activity from açaí, blueberry and goji berry using response surface methodology

Moura¹,

Lima²,

Oldoni

et al. 2018

Emir J Food Agric

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The aim of this study was to determine the best extraction conditions of phenolic compounds present in açaí, blueberry and goji berry fruits using the response surface methodology (RSM). The phenolic compounds profile by high-performance liquid chromatography, antioxidant activity was also determined. A factorial 23 design was used to analyze the effect of the solvent (ethanol and water), time (30 and 60 min) and temperature (30 °C and 60 °C) on the extraction of total phenolic compounds (TPC) and activity antioxidant (AA). The variables time and temperature had a positive effect on antioxidant activity (AA) in their highest levels, 60 min and 60 °C, respectively. The solvent ethanol 800 g/mL was more efficient in TPC extracting with AA in all matrices. Rutin was present in high amounts in blueberry and goji berry, and the myricetin in açaí. The açaí showed higher in vitro antioxidant activity when extracted at 60 °C for 60 min. The high correlation coefficient (0.98) of global response (GR) showed that we can find out single and global response in research with multiple dependent variables. The GR analysis indicated the highest values of the TPC and AA when the fruits were extracted at 60°C for 60 min using ethanol as solvent and it was very useful for simplifying and improving the phenolic compounds extraction performance.

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“…Brazil is a major producer and exporter of propolis collected by A.mellifera (Oldoni et al, 2015). In the last decade, a new type of propolis produced in mangrove areas of northeastern Brazil, known as red propolis due to its reddish coloration, has been identified.…”

Section: Introductionmentioning

confidence: 99%

Chemical characterization and pharmacological action of Brazilian red propolis

et al. 2018

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Among natural products, Brazilian propolis stands out for being considered a source for the discovery of new bioactive compounds. In the last decade, a new Brazilian propolis has been described, known as red propolis due to its reddish pigment. Since then, numerous studies revealing its major components and pharmacological activity have been carried out. Thus, this research had the aim of performing an integrative review of literature on the biological activity of Brazilian red propolis. Scientific studies in the PubMed, SciELO and LILACS databases were reviewed and analyzed using an inductive approach and indirect documentation technique. A total of 418 publications were found, and inclusion and exclusion criteria were subsequently applied, selecting a total of 18 articles. Brazilian red propolis presents numerous pharmacological properties, especially antibacterial, antifungal, antioxidant and anti-inflammatory effects. In addition, the chemical composition of this substance is different from other types of propolis already reported in literature, presenting flavonoids never before described. In this way, its chemical characteristics suggest probable therapeutic use for human consumption Keywords: Flavonoids, Apis millifera, bee. Caracterização química e ação farmacológica da própolis vermelha brasileira ResumoDentre os produtos naturais, a própolis brasileira destaca-se por ser considerada uma fonte para a descoberta de novos compostos bioativos. Na última década, foi descrita uma nova própolis brasileira, conhecida como própolis vermelha devido ao seu pigmento avermelhado. Desde então, inúmeras pesquisas revelando seus componentes majoritários e sua atividade farmacológica têm sido descritas. Dessa forma, esta pesquisa teve o objetivo de realizar uma revisão integrativa da literatura sobre a atividade biológica da própolis vermelha brasileira. Estudos científicos nos bancos de dados PubMed, SciELO e LILACS foram revisados e analisados utilizando-se uma abordagem indutiva e técnica de documentação indireta. Foram encontradas 418 publicações, sendo posteriormente aplicados critérios de inclusão e exclusão, selecionando ao todo 18 artigos. A própolis vermelha brasileira apresenta inúmeras propriedades farmacológicas, destacando-se os efeitos antibacteriano, antifúngico, antioxidante e anti-inflamatório. Além disso, a composição química desta substância é diferente dos demais tipos de própolis já relatados na literatura, apresentando flavonóides que ainda não tinham sido descritos. Dessa forma, suas características químicas sugerem provável uso terapêutico para o organismo humano.

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Chemical Characterization and Optimization of the Extraction Process of Bioactive Compounds from Propolis Produced by Selected BeesApis mellifera

Cited by 31 publications

References 0 publications

A Systematic Review of the Antioxidant Activity of Apiculture Products in Brazil

A Systematic Review of the Antioxidant Activity of Apiculture Products in Brazil

Optimization of phenolic compounds extraction with antioxidant activity from açaí, blueberry and goji berry using response surface methodology

Chemical characterization and pharmacological action of Brazilian red propolis

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