Characterizing the Chemical Landscape in Commercial E-Cigarette Liquids and Aerosols by Liquid Chromatography–High-Resolution Mass Spectrometry

Wilk

et al. 2022

Toxics

A wealth of research has comprehensively documented the harmful effects of traditional cigarette smoking and nicotine on human health. The lower rate of exposure to harmful chemicals and toxic substances offered by alternative electronic smoking devices (e-cigarettes, vaping, etc.) has made these methods of smoking popular, especially among adolescents and young adults, and they are regarded frequently as safer than regular cigarettes. During vaporization of these so-called e-liquids, toxins, carcinogens and various other chemical substances may be released and inhaled by the user. Data on the potential human health effect attendant on exposure to e-vapor are based mainly on animal and in vitro studies. The oral tissues are the first locus of direct interaction with the components of the inhaled vapor. However, the short-term as well as long-term effects of the exposure are not known. The aim of the review is to briefly present data on the effects of the chemical components and toxins of e-cigarette vapor on oral cavity cells and tissues of oral health.

Section: Chemical Components and Toxins Of E-cigarette Aerosolmentioning

confidence: 99%

The Effects of E-Cigarette Aerosol on Oral Cavity Cells and Tissues: A Narrative Review

Wilk

et al. 2022

Toxics

“…Johns Hopkins University researchers applied liquid chromatography-high-resolution mass spectrometry (LC-HRMS) and chemical fingerprinting techniques to characterise e-liquids and aerosols from a selection of popular EC products (Mi-Salt™, Vuse™, Juul™ and Blu™) (Tehrani, Newmeyer et al 2021). They found nearly 2,000 chemicals in these products, the vast majority of which were unidentified.…”

Section: Dual Users Vs Exclusive Cigarette Smokersmentioning

confidence: 99%

Quit Smoking Weapons of Mass Distraction

Chapman¹

2022

ISBN 9781743328538 paperback ISBN 9781743328545 epub ISBN 9781743328590 pdf Contents xi Acknowledgements xiii Abbreviations xv Introduction 1 1 How do most people quit other addictions? 12 2 How we study quitting smoking: a critical look 56 3 Quitting unassisted: before and after "evidence-based" methods 79 4 The modest impact of most popular interventions 5 "Don't try to quit cold turkey" 6 Vaping to quit: the latest mass distraction 7 Insights from qualitative research with unassisted quitters 8 Strategies for reducing smoking across populations 9 Controlling tobacco supply and the endgame References Index ixIt is over 45 years since I first became engaged with questions about how best to reduce tobacco use across populations and the diseases that this causes. Across this time I have met, often worked with and become close friends with many of the best minds in international tobacco control. Seventeen years of that time were spent being deputy editor (1992-97) and then editor (1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007)(2008) of Tobacco Control, the world's first research journal entirely dedicated to reducing tobacco use and the diseases it causes. During those years, it was a rare day when I was not reading and editing one or more of the thousands of papers that were submitted to the journal, even on Christmas Day. There are very few long-term researchers active across the many disciplinary and sub-topic fields of tobacco control whose most important work I've not read.Trying to list and thank everyone who has ever influenced my thinking about tobacco control is an almost boundless task. But the following people are those to whom across different times -including during the writing of this book -I owe a huge collective debt in many ways:

“…Chemical analyses of e-cig vapor have revealed the presence of some of the same toxicants and carcinogens as those found in cigarette smoke, including carbonyl compounds, volatile organic compounds, free radicals, and heavy metals, albeit mostly at substantially lower concentrations [ 23 , 24 ]. E-cig vapor also contains chemicals that are not found in cigarette smoke [ 25 , 26 ]. The latter likely arise from the mixing and heating of humectants [e.g., propylene glycol and glycerol (vegetable glycerin); PG/VG] and flavorings present in e-liquid [ 27 ].…”

Section: Health Consequences: Smoking Vs Vapingmentioning

confidence: 99%

From Tobacco Cigarettes to Electronic Cigarettes: The Two Sides of a Nicotine Coin

Besaratinia

2021

Front. Oral. Health

Tobacco smoking-related diseases, including cardiovascular disease, pulmonary disease, stroke, and cancer in multiple organ sites, are the leading causes of preventable death, worldwide. Youth electronic cigarette use (vaping) is an evolving public health problem in the United States and around the world. Many of the same toxicants and carcinogens present in tobacco smoke are also found in electronic cigarette vapor, although mostly at substantially lower levels. The reduced concentrations of these chemicals in electronic cigarette vapor may imply lower health risk; however, they cannot equate to no risk. To date, the long-term health consequences of vaping are largely unknown. This “Perspective” provides a concise chronology of events leading up to an unprecedented global challenge, namely the convergence of global tobacco epidemic and youth vaping epidemic. Current state of knowledge, outstanding questions in the field, present challenges, and future directions in research are highlighted. The existing data show a continued and dynamic evolution of the converged epidemics. The goal should be to prevent youth vaping while improving smoking cessation strategies. In smokers who are unable or unwilling to quit smoking, the objective should be to provide “provably” safe or less-harmful alternatives, which should “completely” or “substantially” substitute tobacco cigarettes.