Characterization of the inclusion complex of the essential oil of Lantana camara L. and β-cyclodextrin by vibrational spectroscopy, GC–MS, and X-ray diffraction

Characterization of Inclusion Complex of Croton zehntneri Essential Oil and β-Cyclodextrin Prepared by Spray Drying and Freeze Drying

“…In addition to these effects, the OH stretching bands of β-CD were displaced at 3231 cm -1 to 3280 cm -1 in CZEO/β-CD SD and 3253 cm -1 in CZEO/β-CD FD, and the C-H stretch band of β-CD at 2919 cm -1 to 2926 cm -1 in CZEO/β-CD SD and 2906 cm -1 in CZEO/β-CD FD. 8,19 The results of this study corroborate with those obtained by Kfoury et al 45 and Aguiar et al 8 Therefore, the ATR-FTIR technique enabled good evidence to be obtained for complex formation between β-CD and CZEO using the co-precipitation coupled to freeze drying method. The interactions appeared to occur due to the entry of ES aromatic ring into the CD cavity.…”

“…Thus, the application fields of the representative essential oil in the food, medication, cosmetic industries and restricted characteristics can be improved by the formation of inclusion complex with cyclodextrins (CDs) without losing their bioactivity. [18][19][20] CDs are non-toxic cyclic oligosaccharides consisting of 6 (α-cyclodextrin), 7 (βcyclodextrin), 8 (γ-cyclodextrin) or more glucopyranose units linked by α-(1,4) bonds, derived from enzymatic degradation of starch or by metabolism of certain bacteria, such as Bacillus macerans. 21 CDs are ring molecules, but due to the lack of free rotation at the level of bonds between glucopyranose units, they are not cylindrical but, toroidal or coneshaped.…”

“…The total amount of oil in the inclusion complex was determined by method of extraction with solvent proposed by Rocha et al 19 , with some modifications. Briefly, samples equivalent to 10 mg of CZEO of inclusion complex were solubilized with 4.0 mL of distilled water in a test tube sealed with a Bakelite screw cap and extracted with 4.0 mL of n-hexane.…”

“…Raman can be used monitoring of the vibration of C=C bands, which are highly sensitive to the formation of the inclusion complex. 19,47,48 The Raman spectra da β-CD, CZEO, CZEO/β-CD SD and CZEO/β-CD FD inclusion complexes are shown in Figure 5. In the Raman spectrum of CZEO, Figure 5, presents bands around 1643 cm -1 (C=C stretch), related to a double bond nonconjugated of estragole, 1610 cm -1 (C=C aromatic ring), 1298 and 1176 cm -1 (C-O-C stretch), 845 and 818 cm -1 (C-H aromatic ring) and 638 cm -1 (p-aromatic ring).…”

Complexation of an Azo Dye by Cyclodextrins: A Potential Strategy for Water Purification

“…The lines of evidence for the inclusion complex formation are (i) disappearance of peaks, (ii) the formation of diffused peaks, and (iii) the appearance of new peaks . The XRD patterns of all of the three inclusion complexes seem very different from those of the physical mixture, and most of the crystalline diffraction peaks disappear after complexation . The new characteristic peaks of IC-1 occur at 2θ = 15.3, 18.7, and 20.7° with lower intensity.…”