Characterization of cellular elements in healed cultured keratinocyte autografts used to cover burn wounds

Treatment of Pyoderma Gangrenosutn with Cultured Keratinocyte Autografts

“…In contrast to the atrophic, cribriform scars usually seen in healed pyoderma gangrenosum, this patient healed without atrophy or sclerosis. In burn patients grafted with cultured keratinocyte autografts, a neodermis was noted to be induced by the autografts 22,23 . This dermal remodeling induced by the cultured keratinocyte autografts may have prevented the scarring characteristic of healed pyoderma gangrenosum ulcers.…”

Skin substitutes: An overview

“…The epidermis derived from CEA develops fully differentiated basal, spinous, granular and cornified layers, but lacks rete ridges 25,26,50 . This drawback in the dermal–epidermal junction might be responsible for mechanical instability, blisters and late graft loss 51,52 . In other words, the take rate, functional and aesthetic outcomes are dependent on the presence of the dermis.…”

Cultured Epithelial Autografts in the Treatment of Extensive Recalcitrant Keloids

“…24,32 On application, CEAs are undifferentiated and have no granular or cornified cell layer. After 1week, all the normal epidermal layers are present, but there are no rete ridges.…”