Characterization and antioxidant evaluation of phenolic compounds extracted from the protein concentrate and protein isolate produced from pawpaw (<i>Carica papaya</i>Linn.) seeds

Kadiri, Oseni; Akanbi, Charles T.; Olawoye, Babatunde; Gbadamosi, Saka O.

doi:10.1080/10942912.2016.1230874

Cited by 37 publications

(24 citation statements)

References 36 publications

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“…Five phenolic acids, three flavonoids, and two flavonoid glycosides were identified in the ethanolic extract, whereas five phenolic acids were observed in CO 2 -EtOH extract. The phenolic compounds detected in the present work have been previously observed in different parts of papaya fruit; kaempferol-3-O-glycoside, caffeic acid, ferulic acid, p-hydroxybenzoic acid, and p-coumaric acid were identified in the seeds (Kadiri et al 2017); caffeic acid, ferulic acid, and p-coumaric acid were observed in the peel (Nieto Calvache et al 2016); while all the compounds cited in Table 3 were detected in the pulp (Zunjar et al 2015). Kadiri et al (2017) study reported concentrations of these substances between 0.07 and 0.38 mg/g dry extract, ferulic acid was observed as the most abundant compound with concentrations between 0.26 and 0.38 mg/g.…”

Section: Analysis Of Phenolic Compoundssupporting

confidence: 78%

Valorization of papaya (Carica papaya L.) agroindustrial waste through the recovery of phenolic antioxidants by supercritical fluid extraction

et al. 2019

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In this work, supercritical fluid extraction (SFE) for the recovery of phenolic antioxidants from papaya agroindustrial waste (seeds) was explored, making use of neat supercritical CO 2 and CO 2 added with ethanol (CO 2-EtOH). A full factorial design played on in order to evaluate the effect of CO 2 extraction parameters (temperature between 40 and 60°C, and pressure between 10 and 30 MPa) on yield and total phenols content (TPC), then ethanol was applied as a co-solvent and its effect on the recovery of phenolics was analyzed. The SFE was compared to the conventional extraction using ethanol. The antioxidant activity of all extracts was evaluated, and the phenolic composition in selected extracts was assessed by HPLC-ESI-MS. The highest extraction yields (21.02-26.46%) and TPC (15.34-34.23 mgGAE/g) were found in extracts obtained with CO 2-EtOH and ethanol. Good and selective phenolic recovery was obtained by using CO 2-EtOH, (44.81% of TPC recovered). The CO 2-EtOH extracts showed high radical scavenging activity and higher antioxidant effect against lipid oxidation. Some phenolic acids and flavonoids were observed in the extracts with better antioxidants properties. The results showed that SFE is a suitable green technology for the phenolic recovery from papaya agroindustrial waste, and also an alternative for its valorization.

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Section: Analysis Of Phenolic Compoundssupporting

confidence: 78%

Valorization of papaya (Carica papaya L.) agroindustrial waste through the recovery of phenolic antioxidants by supercritical fluid extraction

et al. 2019

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“…It can be conclude from the Table 2 that the concentration average of chlorogenic acid was as much as phenolic derivative found in many plants, one of which is papaya seed [15]. It was found that the average of chlorogenic acid content in papaya seed ethanolic extract was as much as 916.67±32.14 ng/mg.…”

Section: Discussionmentioning

confidence: 86%

Quantification of Quercetin and Chlorogenic Acid in Papaya Seed Ethanol Extract

Pusporini¹,

Baabdullah

Andyka

2019

Asian J Pharm Clin Res

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Objective: The objective of the study was to quantify the quercetin and chlorogenic contained in the ethanolic extract of papaya seed. Methods: Papaya seeds were extracted using the maceration method; then, the qualitative phytochemical analysis was obtained from standard phytochemical screening; furthermore, liquid chromatography–mass spectrometry (LC–MS) examination was used to determine the number of its bioactive compounds. Results: The quantitative examination using LC–MS showed that the content of chlorogenic acid was greater than the quercetin level. Further studies have to be carried out regarding the papaya seed ethanolic extract in vitro inhibition compare to the antibacterial potential of the commercial antibiotics on the tested bacteria species. Conclusion: Our results suggest that papaya seed ethanolic extract quantitatively contains chlorogenic acid greater than quercetin.

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“…[66]. Similarly, C. papaya seeds protein analyzed using the LC-ESI-DAD-MS with largely ferulic acid in addition to flavonoid sugars, justifies the antioxidant efficacies on DPPH (IC 50 0.227 mgmL −1 ) and Fe 2+ chelating (IC 50 0.157 mgmL −1 ) in comparison to ascorbic acid (IC 50 0.109 mgmL −1 ) and EDTA (IC 50 0.091 mgmL −1 ) respectively [67]. The HPLC quantification of plant extracts have shown similar classes of compounds such as chlorogenic acid, ellagic acid, caffeic acid, gallic acid, p-coumaric acid, apigenin, quercetin, rutin and kaempferol which have been repeatedly found in Nigerian plants.…”

Section: Hplc Analysis Of Extracts and Evaluation Of Antioxidant Actimentioning

confidence: 92%

Antioxidants from Nigerian Medicinal Plants: What Are the Evidence?

Aliyu¹,

Achika²,

Adewuyi³

et al. 2020

Lipid Peroxidation Research

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The search for natural antioxidants from plants would continue to be a dominant research interest for many years. This is because of the increasing understanding on the role of oxidative stress in damaging cell structures such as DNA, due to over production of free radicals and reactive oxygen species (ROS) in human systems, which are linked to inflammation, cancer and diabetes. However, phenolic compounds especially from phytochemicals or vegetable foods play important roles in reducing the risk of these diseases and reinforces the importance of natural antioxidants in human health. These antioxidant molecules neutralize or quench the ROS by either hydrogen atom transfer or single electron transfer mechanisms. Thus, the capacity to scavenge ROS and free radicals or inhibits lipid peroxidation is measured quantitatively as the strength of antioxidant activity. Several chemical and biochemical protocols have been used in the evaluation of plant extracts as antioxidants. Overwhelming literature reports have indicated varying degrees of antioxidant efficacies of extracts from Nigerian medicinal plants in comparison to synthetic antioxidants. These efficacies were analyzed to provide insight into the strength of antioxidant activity. This chapter reviewed 250 Nigerian medicinal plants in search of evidence for effective antioxidants.

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Characterization and antioxidant evaluation of phenolic compounds extracted from the protein concentrate and protein isolate produced from pawpaw (Carica papayaLinn.) seeds

Cited by 37 publications

References 36 publications

Valorization of papaya (Carica papaya L.) agroindustrial waste through the recovery of phenolic antioxidants by supercritical fluid extraction

Valorization of papaya (Carica papaya L.) agroindustrial waste through the recovery of phenolic antioxidants by supercritical fluid extraction

Quantification of Quercetin and Chlorogenic Acid in Papaya Seed Ethanol Extract

Antioxidants from Nigerian Medicinal Plants: What Are the Evidence?

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