Characterization and antioxidant activities of acidic polysaccharides from Gynostemma pentaphyllum (Thunb.) Markino

Bo, Li; Zhang, Xiaoyu; Wang, Mingzhu; Jiao, Lili

doi:10.1016/j.carbpol.2015.03.069

Cited by 37 publications

(25 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…and is distributed widely in northeast and southeast Asia [ 1 – 3 ]. G. pentaphyllum has been used in food and supplemental products for hundreds of years in China, where it is mainly distributed south of the Qinling Mountains and Yangtze River [ 4 , 5 ]. According to the traditional Chinese medicine, the taste and nature of G. pentaphyllum are slightly bitter, neutral, and warm [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Isolation, Structures, and Bioactivities of the Polysaccharides fromGynostemma pentaphyllum(Thunb.) Makino: A Review

Shen

Guo

2018

BioMed Research International

View full text Add to dashboard Cite

Polysaccharides obtained from Gynostemma pentaphyllum (Thunb.) Makino have promising prospects in functional food and nutraceuticals due to its broad range of biological activities including antioxidant, immunomodulatory, antitumor, hepatoprotective, neuroprotective, and antifatigue activities. These beneficial biological activities are related to chemical composition and structure of the G. pentaphyllum polysaccharides. The molecular weight, monosaccharide composition, and chemical structures could be influenced by both different extraction/purification techniques employed to obtain polysaccharide enriched products. The purpose of this article is to review previous and current literature regarding the extraction, purification, structural characterization, and biological activity of G. pentaphyllum polysaccharides. This review provides a useful bibliography for the further investigation, production, and application of G. pentaphyllum polysaccharides as functional foods and nutraceuticals.

show abstract

Section: Introductionmentioning

confidence: 99%

Isolation, Structures, and Bioactivities of the Polysaccharides fromGynostemma pentaphyllum(Thunb.) Makino: A Review

Shen

Guo

2018

BioMed Research International

View full text Add to dashboard Cite

show abstract

“…The molecular weight was analyzed using previous method with some slight modifications [ 22 ]. The polysaccharides (10 mg) were dissolved in distilled water (2 mL) and the molecular weight determination of AlAPS and its fractions were by high performance liquid chromatography (HPLC) which was operated with a HPLC system (1260, Agilent Technologies, USA) equipped with a SHODEX SB-806HQ column (8.0 mm × 300 mm) and a refractive index detector.…”

Section: Methodsmentioning

confidence: 99%

“…The reducing power was determined according to the reported method with slight modification [ 22 ]. Each sample (1 mL) was mixed with 2.5 mL phosphate buffer (0.2 mol/L, pH 6.6), and 2.5 mL potassium hexacyanoferrate solution (1%, w/v).…”

Section: Methodsmentioning

confidence: 99%

The Antioxidative, Antiaging, and Hepatoprotective Effects of Alkali‐Extractable Polysaccharides by Agaricus bisporus

Zhang

et al. 2017

Evidence-Based Complementary and Alternative Medicine

View full text Add to dashboard Cite

The aim of this work was designed to investigate the antioxidant, antiaging, and hepatoprotective effects of alkali-extractable polysaccharides (AlAPS) and their three purified fractions (AlAPS-1, AlAPS-2, and AlAPS-3) from Agaricus bisporus in D-galactose induced aging mice. For in vitro antioxidant analysis, both AlAPS and its fractions exhibited moderate reducing power, Fe2+-chelating activities, and potent scavenging activities on hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. The in vivo results demonstrated that the polysaccharides, especially AlAPS-2, showed potential antiaging and hepatoprotective effects by enhancing the antioxidant status, decreasing serum hepatic enzyme activities, and improving the lipid metabolism. This study suggested that the polysaccharides extracted and purified from A. bisporus could be exploited as a potent dietary supplement to attenuate aging and prevent age-related diseases.

show abstract

“…The monosaccharide compositions of the purified fractions were analyzed by a HPLC method [25]. Briefly, 10 mg samples were hydrolyzed with 3 mL of 2 mol/L trifluoroacetic acid (TFA) at 100˝C for 8 h in a sealed tube.…”

Section: Monosaccharide Composition Of Purified Fractionsmentioning

confidence: 99%

Ultrasound-Assisted Extraction, Antioxidant and Anticancer Activities of the Polysaccharides from Rhynchosia minima Root

Jia

Zhang

et al. 2015

Molecules

View full text Add to dashboard Cite

Box-Behnken design (BBD), one of the most common response surface methodology (RSM) methods, was used to optimize the experimental conditions for ultrasound-assisted extraction of polysaccharides from Rhynchosia minima root (PRM). The antioxidant abilities and anticancer activity of purified polysaccharide fractions were also measured. The results showed that optimal extraction parameters were as follows: ultrasound exposure time, 21 min; ratio of water to material, 46 mL/g; ultrasound extraction temperature, 63˝C. Under these conditions, the maximum yield of PRM was 16.95%˘0.07%. Furthermore, the main monosaccharides of purified fractions were Ara and Gal. PRM3 and PRM5 exhibited remarkable DPPH radical scavenging activities and reducing power in vitro. PRM3 showed strong inhibitory activities on the growth of MCF-7 cells in vitro. The above results indicate that polysaccharides from R. minima root have the potential to be developed as natural antioxidants and anticancer ingredients for the food and pharmaceutical industries.

show abstract

Characterization and antioxidant activities of acidic polysaccharides from Gynostemma pentaphyllum (Thunb.) Markino

Cited by 37 publications

References 31 publications

Isolation, Structures, and Bioactivities of the Polysaccharides fromGynostemma pentaphyllum(Thunb.) Makino: A Review

Isolation, Structures, and Bioactivities of the Polysaccharides fromGynostemma pentaphyllum(Thunb.) Makino: A Review

The Antioxidative, Antiaging, and Hepatoprotective Effects of Alkali‐Extractable Polysaccharides by Agaricus bisporus

Ultrasound-Assisted Extraction, Antioxidant and Anticancer Activities of the Polysaccharides from Rhynchosia minima Root

Contact Info

Product

Resources

About