Characteristics comparison between a cyclotron-based neutron source and KUR-HWNIF for boron neutron capture therapy

Tanaka, Hiroki; Sakurai, Yoshinori; Suzuki, Minoru; Masunaga, Shin‐ichiro; Kinashi, Yuko; Kashino, Genro; Liu, Y.; Mitsumoto, T.; Yajima, S.; Tsutsui, Hiroshi; Maruhashi, Akira; Ono, Koji

doi:10.1016/j.nimb.2009.03.095

Cited by 142 publications

(86 citation statements)

References 11 publications

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“…Additionally, its practicality and stability for a BNCT neutron source had been proven by SHI [6]. Next, the proton beam energy was decided.…”

Section: Concept Of the University Of Tsukuba's Neutron Sourcementioning

confidence: 99%

“…The most advanced project is the production of a cyclotronbased treatment device by Sumitomo Heavy Industries Co. (SHI). SHI has completed the production of a cyclotronbased neutron source in 2009, in collaboration with the BNCT team in Kyoto University [6]. The treatment device has been installed in two institutes: the Kyoto University research reactor institute (KURRI) in the Osaka prefecture and in the Southern Tohoku BNCT research center in the Fukushima prefecture.…”

Section: Introductionmentioning

confidence: 99%

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Development of LINAC-Based Neutron Source for Boron Neutron Capture Therapy in University of Tsukuba

Kumada

Naito

Hasegawa

et al. 2018

Plasma and Fusion Research

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Clinical trials of the boron neutron capture therapy (BNCT) have been conducted using research reactors. Recent progresses in the accelerator and accelerator-driven-neutron-source technologies have rendered it possible to generate the substantial number of neutrons required for BNCT treatment, using a compact accelerator, which can be installed in a hospital. The University of Tsukuba launched a project for the development of a compact accelerator-based neutron source for BNCT. For this accelerator, we employed a linear particle accelerator (linac) and the energy of the proton beam was 8 MeV. Beryllium was selected as the neutron target material. To generate sufficient neutron intensity by the reaction between 8 MeV protons and beryllium, the linac accelerates a high current of 5 mA or more. As the target system is critical, we developed a beryllium target system with a threelayered structure to avoid target breakage, caused by massive heat load and blistering, within a short period. The linac-based neutron source for the BNCT is almost complete and we succeeded in generating neutrons, in 2015. Currently, several characteristic measurements are being carried out.

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“…Additionally, its practicality and stability for a BNCT neutron source had been proven by SHI [6]. Next, the proton beam energy was decided.…”

Section: Concept Of the University Of Tsukuba's Neutron Sourcementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Development of LINAC-Based Neutron Source for Boron Neutron Capture Therapy in University of Tsukuba

Kumada

Naito

Hasegawa

et al. 2018

Plasma and Fusion Research

View full text Add to dashboard Cite

show abstract

“…Figure 3 shows an outline of the C-BENS 7 . The generated neutrons are moderated to thermal and epi-thermal neutrons through the moderator consisting of lead, iron, aluminum and calcium fluoride.…”

Section: Pos(inpc2016)127 Pos(inpc2016)127mentioning

confidence: 99%

“…From 1951 until 2012, BNCT has only been performed using reactor-based irradiation systems [3][4][5][6] . In early 2009, the world's first accelerator-based system for BNCT clinical irradiation, Cyclotron-Based Epi-thermal Neutron Source (C-BENS) was completed at Kyoto University Research Reactor Institute (KURRI) 7 . The clinical trial using C-BENS was started in 2012.…”

mentioning

confidence: 99%