Changes in the Skin as a Result of Electric Current

Winer, Louis H.

doi:10.1001/archderm.1958.01560090102020

Cited by 10 publications

(2 citation statements)

References 6 publications

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“…Histopathological examination of the hypopigmented lesion of post-burn area show a fringe of elongated, degenerated cytoplasmic processes, that protude from the lower end of detached basal cells into the sub-epidermal space, in case of electrical burns. 11 In thermal burns, much of the dermal collagen and the cutaneous appendages will be injured. 12…”

Section: Burns-electrical and Thermalmentioning

confidence: 99%

Clinical and histopathological study of postinflammatory hypopigmented macular skin lesions

Hogade¹,

Reddy²

2019

Int J Res Dermatol

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INTRODUCTIONThe color of normal skin comes from a mixture of pigments, of which the predominant is melanin. Pigmentation of the skin predominantly depends on the amount and type of melanin. The degree of skin vascularity, presence of carotene, and thickness of the stratum corneum are other factors that play a role.¹ A blemishless skin is the desire of all human beings. Psychological impact ofpigmentary imperfection provides the impetus for an understanding of pathology of post inflammatory hypopigmented disorders. They are the commonest presentations in patients attending Dermatology OPD. Hence there is a need to study various clinical presentations & histopathology of such lesions. ABSTRACT Background:The objective of the study was to study the various etiologies and ascertain different clinicalpresentations of post-inflammatory hypopigmented lesions. Age and sex distribution, socio economic status, seasonal incidence, most common to rare variants amongst all conditions and to correlate them histopathologically. Methods: 100 patients presenting with Post-inflammatory hypopigmented lesions were selected and detailed history and examination was done. Lab investigations and histopathology was done in those cases. Results: Among the various causes of post-inflammatory hypopigmentation, commonly observed conditions were Pityriasis versicolor, mechanical injuries, Pityriasis alba, burns, leprosy, allergic contact dermatitis, morphoea, discoid lupus erythematosus, psoriasis and Steven's Johnson syndrome. Most common age group affected was in 21-30 years of age. Males (60%) were more than females (40%). People of lower socioeconomic status (55%) presented with post-inflammatory hypo pigmented lesions commonly. History of hypopigmentation ranged from 0-6 months in majority of cases. Upper limbs, trunk and face and neck regions were the most common sites involved. Commonest etiology amongst all cases was pityriasisversicolor, followed by mechanical injuries, PityriasisAlba and burns. Clinical diagnosis correlated with histopathology in these cases. Conclusions:The study concluded that post-inflammatory hypopigmented lesions presented with various manifestations, more common in young, male adults, common in people of lower socioeconomic group. Upper limbs, trunk and face and neck are the common sites involved and histopathology correlated with clinical diagnosis in many cases.

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Section: Burns-electrical and Thermalmentioning

confidence: 99%

Clinical and histopathological study of postinflammatory hypopigmented macular skin lesions

Hogade¹,

Reddy²

2019

Int J Res Dermatol

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“…Several morphological changes of the skin were thought to be useful for the diagnosis of electrical injury (Winer and Levin 1958;Rozsa et al 1967;Hunt et al 1976;Danielsen et al 1978; Thomsen et al b, 1982Nielsen et al 1981;Danielsen et al 1991;Weedon 1992;Xiaohu et al 1995). Histologically, vacuolation and metallisation in the epidermis are known as those changes with diagnostic value.…”

Section: Introductionmentioning

confidence: 99%

A histological study on the mechanism of epidermal nuclear elongation in electrical and burn injuries

Takamiya

Saigusa

Nakayashiki

et al. 2001

International Journal of Legal Medicine

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Epidermal nuclear elongation is one of the most important signs for the diagnosis of electrical injury. In this study, we investigated the mechanism responsible for this phenomenon by comparing the findings from burn injuries and those from contusions. Electrical and burn injuries were made in the dorsal skin of rats using energy ranging from 100 to 790 joules for electrical injury, and 170-690 joules for burn injury. Contusions were also made by compressing the skin with a vice. In electrical and burn injuries, the dermis under the epidermal elongated nuclei was homogeneous and without empty spaces between collagen bundles and the number of dermal fibroblasts per 0.01 mm2 below the damaged epidermis decreased significantly (P < 0.05). The incidence of this change correlated with the depth of denatured dermal collagen fibres and in both types of injuries, dermal cells had no nuclear antigenicity for ubiquitin. The width of the injured epidermis with nuclear elongation decreased significantly (P < 0.05) and the elongated nuclei were parallel to the basal membrane. In electrical injury however, nuclear elongation occurred more frequently near the external root sheath. Nuclear elongation of fibroblasts and external root sheath cells was also found, but those of sebaceous gland cells were not detected. Epidermal elongated nuclei were also found in contusions. The evidence strongly suggests that epidermal nuclear elongation in electrical and burn injuries is due to dermal expansion by heat.

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Physikalisch bedingte Hautreaktionen

Vakilzadeh

1978

Histopathologie Der Haut

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Changes in the Skin as a Result of Electric Current

Cited by 10 publications

References 6 publications

Clinical and histopathological study of postinflammatory hypopigmented macular skin lesions

Clinical and histopathological study of postinflammatory hypopigmented macular skin lesions

A histological study on the mechanism of epidermal nuclear elongation in electrical and burn injuries

Physikalisch bedingte Hautreaktionen

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