Changes in the salivary electrolytic dynamic after sucrose exposure in children with Early Childhood Caries

Abstract

changes in the salivary electrolytic dynamic after sucrose exposure in children with early childhood caries emerson tavares de Sousa, Aline tavares Lima-Holanda & Marinês nobre-dos-Santos * This study sought to explore if the effect of 20% sucrose rinse (SR) on the salivary electrolytic concentration of calcium (Ca 2+), phosphate (Pi) and fluoride (F −) in children with Early Childhood Caries (ECC) is different from healthy children. Here, fifty-eight preschoolers aged 3 to 5 years were divided into 2 groups: caries-free (CF) and with ECC. Changes in saliva flow rate, pH and buffering capacity (BC), as well as in concentrations of Ca 2+ , pi, and f − , and the degree of saturation in relation to hydroxyapatite (DSS HAp) and fluorapatite (DSS FAp) were evaluated. The pre-rinse [Ca 2+ ] was higher in the ECC group in the CF group. A significant increase in [Ca 2+ ] was demonstrated after SR in the cf group (p = 0.05). The [Pi] was reduced by 18% after SR in the ECC group (p = 0.007). The [F-] reduced in both groups after SR (p < 0.000). There was a moderate positive correlation between [Ca 2+ ] and the DSS HAp and DSS FAp. Multivariate analysis showed that children with a higher [Ca 2+ ] in pre-rinse saliva are more likely to have ECC. In conclusion, the effect of a 20% sucrose rinse on the electrolytic concentration of ca 2+ , pi and f − was different when children with ECC were compared with CF children.

Carbonic anhydrase VI activity in saliva and biofilm can predict early childhood caries: A preliminary study

“…Looking beyond the established behavioral, environmental, and socioeconomic risk factors, the pattern of caries susceptibility could be related to biological host factors, which are strongly influenced by saliva properties and composition 5 . Changes in saliva physicochemical properties, such as pH and buffering capacity, and in protein concentration and enzymatic activity could be expected according to the direction of the cariogenic pathway on the tooth surface 6,7 . Consequently, saliva and/or biofilm have been studied regarding their relevance to dental caries physiopathology and their potential use as biomarkers of caries disease 8‐10 .…”

Improving the mechanical behavior of reduced graphene oxide/hydroxyapatite nanocomposites using gas injection into powders synthesis autoclave

“…The chemical formula of this ceramic is Ca 10 (PO 4 ) 6 (OH) 2 , in which the ratio of calcium to phosphate is 1.67, and the crystalline structure of HA is similar to the inorganic part of the human skeletal system. HA has a variety of uses other than orthopedic applications [2][3][4][5] . In recent years, additional researches have been done on calcium phosphates, which indicate the specific value of these ceramic structures [6][7][8][9] .…”

The predictive power of saliva electrolytes exceeds that of saliva microbiomes in diagnosing early childhood caries

“…Na + , Ca 2+ , K + , Mg 2+ , and Cl − ) [66,67]. On the other hand, saliva is also considered as a buffering pool that could shift the dynamic equilibrium between demineralization and remineralization for controlling the dental caries activity [68][69][70]. Inorganic components in saliva can participate in the remineralization of the apatite crystal structure, which directly contributes to the maintenance of enamel integrity and mitigating the damage caused by acid-producing bacteria [67,71].…”