Changes in the refractive index of the human corneal stroma during laser in situ keratomileusis

Patel, Sudi; Alió, Jorge L.; Artola, Alberto

doi:10.1016/j.jcrs.2008.03.022

Cited by 41 publications

(19 citation statements)

References 33 publications

(38 reference statements)

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“…With time, this effect dissipates. 18,19 In contrast to the studies of Patel et al, 18,19 Savini et al 20 report a decreased keratometric refractive index after myopic PRK and LASIK.…”

Section: Discussionmentioning

confidence: 91%

Correlation between estimated and measured corneal ablation and refractive outcomes in laser in situ keratomileusis for myopia

Lackerbauer¹,

Grüterich²,

Ulbig³

et al. 2009

Journal of Cataract and Refractive Surgery

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“…With time, this effect dissipates. 18,19 In contrast to the studies of Patel et al, 18,19 Savini et al 20 report a decreased keratometric refractive index after myopic PRK and LASIK.…”

Section: Discussionmentioning

confidence: 91%

Correlation between estimated and measured corneal ablation and refractive outcomes in laser in situ keratomileusis for myopia

Lackerbauer¹,

Grüterich²,

Ulbig³

et al. 2009

Journal of Cataract and Refractive Surgery

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“…A variation in the hydration of the corneal stroma may be cause of the underablation or overablation of stromal tissue (Kim & Jo ; Patel et al. , ). As for LASIK, the flap is required to be lifted before excimer laser ablation.…”

Section: Discussionmentioning

confidence: 99%

Two‐years results of small‐incision lenticule extraction and wavefront‐guided laser in situ keratomileusis for Myopia

Kobashi

Kamiya

Igarashi

et al. 2017

Acta Ophthalmologica

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“…A variation in hydration of the corneal stroma is the most likely cause for underablation or overabla- FS-LASIK With SMILE/Ganesh & Gupta tion of stromal tissue. [13][14][15] In LASIK, the flap needs to be lifted before excimer laser ablation can be performed. This exposes the stroma to hydration changes before refractive correction.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Visual and Refractive Outcomes Following Femtosecond Laser-Assisted LASIK With SMILE in Patients With Myopia or Myopic Astigmatism

Ganesh¹,

Gupta²

2014

J Refract Surg

187

147

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ASIK is the most popular refractive surgery for myopic laser correction to date. The use of femtosecond laser-assisted LASIK (FS-LASIK) offers the creation of more predictable flaps with regard to flap thickness, diameter, and hinge width. 1,2Even with high success rates, side effects such as increased postoperative dryness, reduced biomechanical corneal strength, induction of higher-order aberrations (HOAs), postoperative glare, halos, and flap-related complications remain. 3-5More recently developed is refractive lenticule extraction, which uses a femtosecond laser to create an intrastromal corneal lenticule (the removal of which alters the shape of the cornea), thereby correcting myopia. It encompasses two different techniques: femtosecond lenticule extraction (FLEX) and small-incision lenticule extraction (SMILE).SMILE is a more recent flapless subtype in which the lenticule is extracted through a small arcuate incision (2 to 4 mm). This allows for greater stability because most of the Bowman's layer remains intact.Studies have shown that SMILE is associated with lower topographic changes and less inflammation and keratocyte apopotosis than FS-LASIK, particularly for higher levels of correction of myopia. 6,7 Because the procedure is flapless, most flap-related complications are not observed with SMILE.The aim of the current study was to evaluate the efficacy and safety of SMILE compared with FS-LASIK. Our primary hypothesis (null hypothesis) states that SMILE is better or comparable to LASIK for correction of myopia in terms of refractive accuracy and quality of vision (ie, postoperative aberrations and contrast sensitivity). Primary outcome measures were refractive efficacy, predictability, and safety, postoperative contrast sensitivity wavefront aberrations, and tear film abnormalities. L ABSTRACT PURPOSE: To compare the visual and refractive outcomes of femtosecond laser-assisted LASIK with smallincision lenticule extraction (SMILE) in terms of visual acuity, contrast sensitivity, aberrations, and dry eye. METHODS:A single-center prospective randomized study in which patients diagnosed as having myopia presenting for refractive correction were allocated to either a LASIK or SMILE group. The primary outcome measures were refractive efficacy, predictability, and safety, postoperative contrast sensitivity, aberrations, and dry eye status. Patients were followed up at days 1 and 15 and 3 months; postoperative uncorrected visual acuity (UCVA), aberrations, dry eye, and contrast sensitivity were recorded and compared to preoperative data. Two postoperative subjective questionnaires were used to assess pain, pricking sensation, redness, glare, and overall patient satisfaction. RESULTS:At day 1 postoperatively, 48 (96%) of 50 eyes in the SMILE group achieved a UCVA of 20/20 compared with 46 (92%) of 50 eyes in the LASIK group. At day 15 postoperatively, contrast sensitivity was similar in the two groups (P = .15), but by 3 months, it was better in the SMILE group than the LASIK group at all spatial frequencies (...

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Changes in the refractive index of the human corneal stroma during laser in situ keratomileusis

Abstract: Photoablation increased the refractive index of the stroma, and the increase was influenced by treatment time. Hydration of the stroma was 1.8 mgm/mgm greater in the microkeratome group than in the femtosecond laser group.

Cited by 41 publications

References 33 publications

Correlation between estimated and measured corneal ablation and refractive outcomes in laser in situ keratomileusis for myopia

Correlation between estimated and measured corneal ablation and refractive outcomes in laser in situ keratomileusis for myopia

Two‐years results of small‐incision lenticule extraction and wavefront‐guided laser in situ keratomileusis for Myopia

Comparison of Visual and Refractive Outcomes Following Femtosecond Laser-Assisted LASIK With SMILE in Patients With Myopia or Myopic Astigmatism

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