Changes in the management and survival rates of patients with oral cancer: a 30-year single-institution study

Seo, Bo-Yun; Lee, Chung-O; Kim, Jin Wook

doi:10.5125/jkaoms.2016.42.1.31

Cited by 10 publications

(6 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…OSCC is detected in the late stages in the majority of cases 26 , as observed in this study with 61.5% of the men diagnosed at stage III/IV, whereas 62.5% of the women were diagnosed at stage I/II (p=0.013). This difference might be explained by women attending medical appointments more regularly than men, favouring early diagnosis of the disease.…”

Section: Discussionsupporting

confidence: 73%

Clinicopathological parameters of oral squamous cell carcinoma in Florianópolis

Martini¹,

<²,

Bordignon³

et al. 2019

J Oral Diag

View full text Add to dashboard Cite

Oral squamous cell carcinoma (OSCC) is one of the most common cancers and presents the highest mortality rate of head and neck tumours. The aim of this study was to evaluate the clinical and histological features of patients with OSCC in Florianópolis, Santa Catarina, Brazil between 2006 and. Demographic and clinical characteristics such as age, gender, tobacco and alcohol consumption, anatomical site, clinical stage, and treatment were retrospectively collected from histopathological and medical reports. Of 196 patients with OSCC, 82.14% were male with a mean age of 58.28±10.45 years. Tobacco and alcohol consumption was reported in 88.76% and 75.9% of patients, respectively. The tongue was the anatomical site most affected (25.13%) and ulcers were the most prevalent clinical aspect (95.21%). A total of 103 (52.55%) patients were diagnosed with advanced stage (III/IV). Regarding treatment, 59.24% received more than one type of therapy, while 39.67% were treated exclusively with surgery. Regarding histological differentiation, 72.9% of the cases were moderately/poorly differentiated, 23.8% had vascular invasion, 17.9% had lymphatic invasion, and perineural invasion was observed in 29.5% of the patients. The survival rate showed a worse prognosis for patients diagnosed at stage III/ IV and the primary tumour was located in the inferior level of the mouth in 80% of these cases. The results showed that the majority of cases were diagnosed at an advanced stage, compromising treatment and prognosis. Educational and preventive measures should be improved in an effort to allow for early diagnosis.

show abstract

Section: Discussionsupporting

confidence: 73%

Clinicopathological parameters of oral squamous cell carcinoma in Florianópolis

Martini¹,

<²,

Bordignon³

et al. 2019

J Oral Diag

View full text Add to dashboard Cite

show abstract

“…Therefore, the prevention of oral cancer, earlier diagnosis, and active treatment of early stage disease may be the best means of improving 5-year survival rates and quality of life after treatment. Achieving these goals may require the enforcement of public education and social efforts relevant to early diagnosis through regular oral examinations by expert clinicians [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

Low Survival Rates of Oral and Oropharyngeal Squamous Cell Carcinoma

Campion

Ribeiro

Luiz

et al. 2017

International Journal of Dentistry

View full text Add to dashboard Cite

Aim To assess the epidemiological and clinical factors that influence the prognosis of oral and oropharyngeal squamous cell carcinoma (SCC). Methods One hundred and twenty-one cases of oral and oropharyngeal SCC were selected. The survival curves for each variable were estimated using the Kaplan-Meier method. The Cox regression model was applied to assess the effect of the variables on survival. Results Cancers at an advanced stage were observed in 103 patients (85.1%). Cancers on the tongue were more frequent (23.1%). The survival analysis was 59.9% in one year, 40.7% in two years, and 27.8% in 5 years. There was a significant low survival rate linked to alcohol intake (p = 0.038), advanced cancer staging (p = 0.003), and procedures without surgery (p < 0.001). When these variables were included in the Cox regression model only surgery procedures (p = 0.005) demonstrated a significant effect on survival. Conclusion The findings suggest that patients who underwent surgery had a greater survival rate compared with those that did not. The low survival rates and the high percentage of patients diagnosed at advanced stages demonstrate that oral and oropharyngeal cancer patients should receive more attention.

show abstract

“…While it does not stand in the list of top 10 malignancies worldwide the scenario is very dissimilar in Pakistan where it is the most common cancer amongst men and second only to breast amongst women. It remains a significant health concern in Pakistan as we are witnessing a rising incidence, mortality (IARC Globocan., 2018), and poor prognosis with majority of patients presenting at an advanced stage (Seo et al, 2016). This mandates discovery of tools capable of predicting prognosis by utilizing minimally invasive techniques.…”

Section: Research Articlementioning

confidence: 99%