Changes in plasma enzyme activities in professional racing cyclists.

Abstract

Objective-To reports changes in plasma levels in professional racing cyclists. Methods-Plasma levels of the intracellular enzymes aspartate aminotransferase, alanine aminotransferase, y glutamyl transpeptidase, lactate dehydrogenase, and alkaline phosphatase were measured resting and after exercise in professional cyclists participating in two road races: Vuelta Cicista a Valencia (800 km, beginning of the cyclist season), and the top rank race Vuelta a Espafia (2700 km, at the end of cyclist season). Results-A significant increase in plasma aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase was observed at the end of the race over the corresponding paired start values (P < 0.05). The increase in plasma lactate dehydrogenase after the race was only statistically significant (P < 0-05) in the Vuelta a Espafia. The longer the duration of the cycle tour race, the greater were the increases in aspartate aminotransferase and alanine aminotransferase levels. The high levels returned to their start values during the overnight resting period. Conclusions-The presence of these enzymes in the blood is probably due to mechanically damaged muscle cells leaking their contents into the interstitial fluid. (BrJt Sports Med 1996;30:122-124)

Short-term effects of treadmill exercise on metabolic, physiological and hemodynamic functions of apparently healthy individuals.

“…The higher plasma liver enzymes activity observed in the subjects after exercise can be associated with the leaking of these enzymes from mechanically damaged muscle cells into the surrounding interstitial fluids. This finding is in line with the report of a study carried out by Mena et al (1996) 22 , which reported a significant increase in the plasma enzyme level. The mean serum ALP activities of the subjects after the exercise were significantly higher than their mean serum ALP activities before the exercise.…”

Acute hepatic response to diet modification and exercise-induced endotoxemia during a laboratory-based duathlon

“…Endurance and resistance training exercise also promote changes in liver damage markers in humans, as previously reported during cycling and running competitions [10,13,35,41,49,52,57].…”

Pattern of some Liver Enzymes and Cardiovascular Changes during a Trademill Exercise

“…4 However, physical exercise increases serum level of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). 5 It was also reported that high intensity, short duration exercise resulted in greater enzyme than low intensity, long term exercise and the longest increase corresponded with the perception of muscle soreness. 6 Temporary elevations of the liver enzymes have been seen during and immediately after a routine exercise regimen.…”

“…However, dehydration and heart strokes are the key word problems with over exercising or the use of Saunas to induce weight loss through massive sweating of the fluid. 5 Exercise increases serum alkaline phosphate bone isoform B1 and B2, it is suggested that when a young jogged in a moderate temperature of 40°C for 40 minutes, the level of the serum B2 and parathyroid hormone increased, all the changes turn towards baseline within 20 minutes after exercise. 7 The results of this study designed to assess the acute or short-term effect of treadmill exercise on liver functions of these individuals and the findings from previous multiple studies will provide an empirical evidence that will guide the use of physical exercise to improve the health of both apparently healthy as well as sick individuals in our community and to assess physical state of our students.…”