Changes in pain and quality of life in depressed individuals with spinal cord injury: does type of pain matter?

Abstract

Objective: To examine the association of neuropathic and nociceptive pain severity and interference with quality of life (QoL) in persons with spinal cord injury (SCI) who underwent a randomized controlled 12-week trial of an antidepressant to treat depression. A secondary objective was to assess the effect of changes in pain on mobility and physical independence. Design: Multivariable ANCOVA models controlling for relevant demographic covariates, treatment condition, and baseline pain and QoL were used. Setting: Six rehabilitation centers. Participants: Of the 133 persons who were randomized into the trial, 108 provided pain severity and interference ratings through follow-up. Interventions: Not applicable. Outcome Measures: The Satisfaction with Life Scale and the physical and mental component summary scores of the 12-Item Short-Form Health Survey (SF-12). Secondary outcome measures included the mobility and physical independence subscales of the Craig Handicap Assessment and Reporting Technique (CHART). Results: Broadly, few associations between pain and QoL were evident. Results revealed relationships between lower baseline nociceptive pain interference and higher satisfaction with life and mental health-related QoL at 12 weeks. Similarly, lower neuropathic pain interference was associated with change in physical independence, but unrelated to mobility. Conclusions: Pain interference over time may be differentially related to QoL outcomes based on the type of pain following SCI, but overall, there were no extensive relationships between pain and QoL in this sample of depressed persons with SCI.

Quality of life after spinal cord injury: The impact of pain

“…A second study found that those with NP had significantly lower QoL compared to those reporting no pain or nociceptive pain (Andresen et al., ). A third study found no extensive relationship between pain phenotype and QoL although the study population comprised patients with a major depressive disorder, limiting interpretation of the results (Richardson et al., ). Limitations in studies to date include failure to employ a detailed QoL measure and that data were not drawn from in a national population sample.…”

Atuação fisioterapêutica e qualidade de vida de pacientes com Traumatismo Raquimedular: uma revisão integrativa

“…De acordo com Mota; Ribeiro (2016), em estudo transversal composto de 118 pacientes com idade média de 34,7 anos, observou-se alta prevalência de lesão por pressão em pessoas com TRM, sendo a avaliação da qualidade de vida elucidada por uma insatisfação significativa referente aos aspectos físicos. Outro estudo com abordagem metodológica semelhante, identificou a dor como um fator que diminui a QV dos pacientes estudados 11 .…”

The Role Of Mindfulness In Quality Of Life Of Persons With Spinal Cord Injury: A Cross-Sectional Study

“…The presence of pain, and in particular, the location of the pain, is associated with functional independence. For instance, if individuals with SCI have pain in the upper extremities, it may impact their ability to use a wheelchair and perform basic activities of daily living (24). Taken together, some sociodemographic and injuryrelated variables are likely to contribute to QOL in PwSCI; however, other psychological factors also affect adaptation outcomes.…”