Changes in Alcohol Intake and Mortality

Grønbæk, Morten; Johansen, Ditte; Becker, Ulrik; Hein, Hans Ole; Schnohr, Peter; Jensen, Gorm; Vestbo, Jørgen; Sørensen, Thorkild I A

doi:10.1097/01.ede.0000112219.01955.56

Cited by 69 publications

(21 citation statements)

References 25 publications

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“…The reduction of all-cause mortality in moderate wine drinkers could be attributed to a lower death from cancer (by 20 %) and from other causes (by 28 to 42 %) shown in Figure 1. The specificity of wine for lowering the risk of all-cause mortality and cancer has been confirmed recently by Gronbaek et al (11). It was only in wine drinkers that the all-cause mortality was lowered by more than 20 % for an intake of up to 3 drinks per day.…”

Section: Type Of Alcohol and All-cause Mortalitymentioning

confidence: 75%

Alcohol and Mortality from All Causes

et al. 2004

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A large number of prospective studies have observed an inverse relationship between a moderate intake of alcohol and coronary heart disease morbidity and mortality. Concerning death from all-causes, results are not unanimous. Alcohol intake was associated with a protection of all-cause mortality in England and USA physicians and the large study of the American Cancer Society. None of these studies separated the effects of different alcoholic beverages. In our prospective studies in France on 35 000 middle-aged men, we observed that only wine at moderate intake, was associated with a protective effect on all-cause mortality. The reason was that in addition to the known effect on cardiovascular diseases, a very moderate intake of wine, protected also from cancer and other causes as confirmed by Gronbaek in Denmark. Our recent results also indicate that the protective effect of a moderate intake of wine on all-cause mortality is observed at all levels of blood pressure and serum cholesterol.

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Section: Type Of Alcohol and All-cause Mortalitymentioning

confidence: 75%

Alcohol and Mortality from All Causes

et al. 2004

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“…Epidemiological studies [41][42][43][44][45][46][47] The independent effect of alcohol consumption was not observed in the pathogenesis of OSF [37,48,49], thus we suppose that it might function in a relatively late phase of the carcinogenic process.…”

Section: Discussionmentioning

confidence: 99%

Synergistic effects of betel quid chewing, tobacco use (in the form of cigarette smoking), and alcohol consumption on the risk of malignant transformation of oral submucous fibrosis (OSF): a case-control study in Hunan Province, China

Liu

Shen

Xiong

et al. 2015

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

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“…This near-unanimous quantification is consistent with the American Heart Association guidelines, 20 but stands in contrast to the literature. Even low to moderate levels of alcohol consumption have been shown to impose harm, including higher risk of mortality (< 2 drinks per day), 28 atrial fibrillation (1–2 drinks per day), 10 and hypertension (3 drinks per day). 29 In the context of this scientific conflict, that those who believed alcohol to be heart healthy consume nearly 50% more alcohol than those who do not has important implications regarding dissemination of science and counseling of patients.…”

Section: Discussionmentioning

confidence: 99%

Perceptions, Information Sources, and Behavior Regarding Alcohol and Heart Health

Whitman

Pletcher

Vittinghoff

et al. 2015

The American Journal of Cardiology

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Despite the equipoise regarding alcohol’s cardiovascular effects and absence of relevant rigorous controlled trials, the lay press frequently portrays alcohol as “heart healthy.” The public perception of alcohol’s heart effects, the sources of those perceptions, and how they may affect behavior are unknown. We performed a cross-sectional analysis of data obtained between March, 2013 and September, 2014 from consecutive participants enrolled in the Health eHeart Study. Of 5,582 participants, 1,707 (30%) viewed alcohol as heart healthy, 2,157 (39%) viewed it as unhealthy, and 1,718 (31%) were unsure. Of those reporting alcohol as heart healthy, 80% cited lay press as a source of their knowledge. After adjustment, older age (odds ratio 1.11), higher education (odds ratio, 1.37), higher income (odds ratio 1.07), US residence (odds ratio 1.63) and coronary artery disease (CAD) (odds ratio 1.51) were associated with perception of alcohol as heart healthy (all p < 0.003). Ever smokers (odds ratio 0.76, p = 0.004) and those with heart failure (HF) (odds ratio 0.5, p = 0.01) were less likely to cite alcohol as heart healthy. Those perceiving alcohol as heart healthy consumed on average 47% more alcohol on a regular basis (95% confidence interval 27–66%, p < 0.001). In conclusion, among more than 5,000 consecutive Health eHeart participants, approximately one third believed alcohol to be heart healthy, and the majority cited the lay press as the origin of that perception. Those with a perception of alcohol as heart healthy drink substantially more alcohol.

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Changes in Alcohol Intake and Mortality

Abstract: Persons with stable patterns of light and moderate alcohol intake had the lowest all-cause mortality. Individual changes in alcohol intake were followed by corresponding changes in mortality.

Cited by 69 publications

References 25 publications

Alcohol and Mortality from All Causes

Alcohol and Mortality from All Causes

Synergistic effects of betel quid chewing, tobacco use (in the form of cigarette smoking), and alcohol consumption on the risk of malignant transformation of oral submucous fibrosis (OSF): a case-control study in Hunan Province, China

Perceptions, Information Sources, and Behavior Regarding Alcohol and Heart Health

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