Chagas cardiomyopathy and serologic testing in a small rural hospital in Chiapas, Mexico

Capps, Linnea; Abad, Begoña Guirao

doi:10.1590/s1020-49892004000500009

Cited by 10 publications

(9 citation statements)

References 7 publications

(4 reference statements)

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“…Supported, in part, by local health authorities, they performed a survey throughout the state, covering several topics: clinical features (cardiology, gastroenterology), entomology, serology, sociology, and parasitology, but not reservoirs. This situation shows that Chagas disease in Mexico is there to be found when it is looked for (LozanoKasten 1997, Capps & Begona 2004, Coll-Cardenas et al 2004). Guerrero state also became important as an increasing number of studies were published there.…”

Section: Discussionmentioning

confidence: 97%

Chagas disease in Mexico: an analysis of geographical distribution during the past 76 years - A review

Cruz-Reyes

Pickering-López

2006

Mem. Inst. Oswaldo Cruz

131

104

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Section: Discussionmentioning

confidence: 97%

Chagas disease in Mexico: an analysis of geographical distribution during the past 76 years - A review

Cruz-Reyes

Pickering-López

2006

Mem. Inst. Oswaldo Cruz

131

104

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“…23 One retrospective analysis of heart failure patients in Chiapas, Mexico, reported a prevalence rate of 82.5% for Chagas disease. 24 Some cite these facts as examples of how Mexico has neglected the evidence of a tremendous epidemic of Chagas disease. 4,21,[25][26][27][28] Only 13% of study participants had heard of Chagas disease, and this group as a whole had a poor understanding of the epidemiology and natural course of the disease.…”

Section: Discussionmentioning

confidence: 99%

Chagas Disease Awareness Among Latin American Immigrants Living in Los Angeles, California

Sanchez¹,

Traina²,

Hernández³

et al. 2014

The American Society of Tropical Medicine and Hygiene

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Abstract. Approximately 300,000 persons have Chagas disease in the United States, although almost all persons acquired the disease in Latin America. We examined awareness of Chagas disease among Latin American immigrants living in Los Angeles, California. We surveyed 2,677 persons (age range = 18-60 years) in Los Angeles who resided in Latin America for at least six months. A total of 62% of the participants recalled seeing triatomines in Latin America, and 27% of the participants reported triatomine bites at least once per year while living abroad.

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“…In Mexico, the reported seroprevalence rates have ranged from 19.4% in Yucatán to 82.5% in Chiapas [14][15] ; in Brazil, the prevalence has been reported to range from 20% in São Paulo to 48% in Bahia [5][6][7][8][9] . All authors agree that seroprevalence is higher in HF patients; however, the point of interest is to ascertain whether the HF syndrome in seropositive patients is a consequence of CChC.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Trypanosoma cruzi antibodies and inflammatory markers in uncompensated heart failure

Bravo-Tobar

Parra²,

Pérez

et al. 2011

Rev. Soc. Bras. Med. Trop.

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Introduction: Heart failure (HF) represents the final stage of chronic chagasic cardiomyopathy (CChC). The diagnosis of CChC is based on the demonstration of anti-Trypanosoma cruzi antibodies (aTcAg) and clinical and epidemiological data. In Venezuela, there are no data about the prevalence of chagasic HF. The aim of this study was to determine the epidemiological, clinical, and inflammatory risk factors associated with seronegative or seropositive HF patients. Methods: We performed a cross-sectional study in the Venezuelan central-west states among a healthy rural population and in patients admitted to the emergency room with uncompensated HF. Results: The seroprevalence rates of Trypanosoma cruzi antibodies were 11.2% and 40.1% in the healthy population and in HF patients, respectively. Seropositivity in healthy individuals was associated with age, knowledge on triatomine vectors, and having seen wild reservoirs in the house; in HF patients, with contact with the vector and previous clinical diagnosis of Chagas' disease; and in both groups taken together, with age, knowledge on triatomines, and HF. Seropositive patients had prolonged QRS, decreased ejection fraction, and high serum magnesium, all significant as compared with HF seronegative cases. Left atrium enlargement and ventricular hypertrophy were most frequently observed in HF seronegative patients. CRP, IL6, ILβ1, IL2, and FNTα were elevated in 94.5%, 48%, 17.8%, 13.7%, and 6.9% of HF patients, respectively, but only IL2 levels were associated with chagasic HF. Conclusions: There is a high prevalence of aTcAg in HF patients from the central-west region of Venezuela, and their epidemiological, clinical, and inflammatory features are discreetly different as compared with those of seronegative cases.

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Chagas cardiomyopathy and serologic testing in a small rural hospital in Chiapas, Mexico

Abstract: This research adds to the evidence that Chagas' disease continues to be a major cause of heart failure in some areas of Mexico and that there continues to be a risk of transmission by blood transfusion if donated blood is not consistently screened.

Cited by 10 publications

References 7 publications

Chagas disease in Mexico: an analysis of geographical distribution during the past 76 years - A review

Chagas disease in Mexico: an analysis of geographical distribution during the past 76 years - A review

Chagas Disease Awareness Among Latin American Immigrants Living in Los Angeles, California

Prevalence of Trypanosoma cruzi antibodies and inflammatory markers in uncompensated heart failure

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