“…Neurohaemal organs where neurosecretory endings are in close contact with blood vessels have been described in many animals [76,[85][86][87] including annelids (infracerebral complex) [88,89] , mollusks [90] (e.g. the neurosecretory system of the vena cava in Octopus ) [91] , insects (pars intercerebralis -corpus cardiacum -corpus allatum system), crustaceans (X-organ and other organs) [87,92] , millipedes [93,94] , nemerteans [95] , tunicates [86] , cephalochordates [96] , and vertebrates (the various circumventricular organs) [86] .…”